DT-Web

DB03506 - 9-Deazaadenine


Identification
Name 9-Deazaadenine
Accession Number DB03506 (EXPT00355)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 133.1307
Groups experimental
Monoisotopic Weight 133.05142118
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Adenine phosphoribosyltransferase
Name Adenine phosphoribosyltransferase
Gene Name APRT
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.434

Predictions


Id Partner name Gene Name Score
4271 Anthranilate phosphoribosyltransferase trpD 0.0661
2794 Orotate phosphoribosyltransferase pyrE 0.0604
4269 Hypoxanthine-guanine phosphoribosyltransferase, putative HGPRTase 0.0561
87 Hypoxanthine-guanine phosphoribosyltransferase HPRT1 0.0468
2751 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0299
4755 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0299
4752 Peroxisomal trans-2-enoyl-CoA reductase PECR 0.0299
6288 Low molecular weight phosphotyrosine protein phosphatase ACP1 0.0263
6832 Serine/threonine-protein kinase SRPK2 SRPK2 0.0255
4606 Purine trans deoxyribosylase ptd 0.0244
4692 A/G-specific adenine glycosylase mutY 0.0243
1958 S-methyl-5-thioadenosine phosphorylase MTAP 0.0233
3679 MTA/SAH nucleosidase mtnN 0.0229
851 5'-AMP-activated protein kinase subunit beta-2 PRKAB2 0.0212
388 AMP deaminase 1 AMPD1 0.0212
775 Acetyl-CoA carboxylase 2 ACACB 0.0209
821 Acetyl-coenzyme A synthetase 2-like, mitochondrial ACSS1 0.0179
704 Long-chain-fatty-acid--CoA ligase 1 ACSL1 0.0179
386 Acetyl-coenzyme A synthetase, cytoplasmic ACSS2 0.0179
297 Adenylate cyclase type 1 ADCY1 0.0179
2684 Histidine triad nucleotide-binding protein 1 HINT1 0.017
2264 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase cobT 0.0167
1291 cAMP response element-binding protein CREB1 0.0167
281 5'-AMP-activated protein kinase subunit beta-1 PRKAB1 0.0163
748 5'-AMP-activated protein kinase catalytic subunit alpha-1 PRKAA1 0.0155
6021 Adenosine kinase ADK 0.0147
4198 Fructose-1,6-bisphosphatase 1 FBP1 0.014
10 Glycogen phosphorylase, liver form PYGL 0.0127
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0126
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0117
2358 cAMP-specific 3',5'-cyclic phosphodiesterase 4D PDE4D 0.0112
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0103
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0056
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0056
4992 Cytochrome c peroxidase Not Available 0.0056
5577 N5-carboxyaminoimidazole ribonucleotide mutase purE 0.0055
2300 Lysozyme E 0.0055
3633 Lysozyme R 0.0055
5597 Lysozyme 17 0.0055
3792 KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase eda 0.0055
4695 UPF0124 protein yfiH yfiH 0.0055
5590 N utilization substance protein B homolog nusB 0.0055
5588 Cell division protein FtsY TM_0570 0.0055
5598 Glycerol uptake operon antiterminator-related protein TM_1436 0.0055
5587 Iron(III)-binding periplasmic protein fbpA 0.0055
5591 Complement component C8 gamma chain C8G 0.0055
5582 Regulator of transcription; stringent starvation protein A sspA 0.0055
2838 Ribose-5-phosphate isomerase A rpiA 0.0055
2952 Ribose-5-phosphate isomerase A rpiA 0.0055
5595 Ribose-5-phosphate isomerase A rpiA 0.0055
5593 Transferase Not Available 0.0055
4238 50S ribosomal protein L4 rplD 0.0055
5578 50S ribosomal protein L4 rplD 0.0055
6173 50S ribosomal protein L4 rplD 0.0055
6219 50S ribosomal protein L4 rplD 0.0055
5581 Beta-fructosidase bfrA 0.0055
5060 Intron-associated endonuclease 1 ITEVIR 0.0055
4375 Glutamine synthetase 1 glnA1 0.0055
5600 Pyruvate decarboxylase pdc 0.0055
5592 Ribonucleoside-diphosphate reductase subunit beta nrdF 0.0055
5583 RNA 3'-terminal phosphate cyclase rtcA 0.0055
5586 Pleckstrin homology domain-containing family A member 1 PLEKHA1 0.0055
5575 Short tail fiber protein 12 0.0055
5580 Hexon protein PII 0.0055
5574 Invasin YPTB1668 0.0055
3085 Molybdopterin-guanine dinucleotide biosynthesis protein A mobA 0.0051
3729 Citrate synthase gltA 0.0051
4575 Citrate synthase cit 0.0051
4580 Citrate synthase gltA 0.0051
5328 Prostaglandin F synthase Tb11.02.2310 0.0051
3132 Tryptophan synthase alpha chain trpA 0.005
6568 Tryptophan synthase alpha chain trpA 0.005
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0049
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0049
1467 Tumor necrosis factor ligand superfamily member 13B TNFSF13B 0.0049
5006 RNASE4 protein RNASE4 0.0048
4533 Glyoxalase family protein BC_1747 0.0048
5599 3-carboxy-cis,cis-muconate cycloisomerase pcaB 0.0048
2555 Pol polyprotein pol 0.0048
3242 Pol polyprotein gag-pol 0.0048
3471 Pol polyprotein gag-pro-pol 0.0048
5256 Pol polyprotein pol 0.0048
6469 Pol polyprotein gag-pol 0.0048
6565 Pol polyprotein Not Available 0.0048
2521 Cell division protein ftsZ ftsZ 0.0048
3301 Cell division protein ftsZ ftsZ 0.0048
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0047
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0047
857 Malate dehydrogenase, mitochondrial MDH2 0.0046
2149 Angiogenin ANG 0.0045
2603 Beta-lactamase II blm 0.0045
3583 6-phosphogluconolactonase pgl 0.0045
1123 Eosinophil cationic protein RNASE3 0.0044
2697 Uridine-cytidine kinase 2 UCK2 0.0044
2869 1-deoxy-D-xylulose 5-phosphate reductoisomerase dxr 0.0043
2942 Sialidase nanH 0.0043
3546 Sialidase nedA 0.0043
2805 Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 HS3ST3A1 0.0042
3486 Fumarate hydratase class II fumC 0.0042
2452 Tryptophanyl-tRNA synthetase trpS 0.0042
2286 Isocitrate dehydrogenase [NADP] icd 0.0042
2302 Isocitrate dehydrogenase [NADP] icd 0.0042
2771 Isocitrate dehydrogenase [NADP] icd 0.0042
941 Betaine--homocysteine S-methyltransferase 1 BHMT 0.0042
332 Beta-lactamase blaZ 0.0041
2478 Beta-lactamase ampC 0.0041
2613 Beta-lactamase ampC 0.0041
2635 Beta-lactamase ampC 0.0041
2700 Beta-lactamase penP 0.0041
5445 Beta-lactamase blaB 0.0041
6019 Beta-lactamase SHV-7 0.0041
6701 Beta-lactamase cphA 0.0041
411 Glycine N-methyltransferase GNMT 0.0041
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.004
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.004
3478 Glucose-1-phosphate thymidylyltransferase rmlA 0.0039
4277 Glucose-1-phosphate thymidylyltransferase rmlA 0.0039
5579 Carboxypeptidase B CPB1 0.0037
3384 Macrophage migration inhibitory factor MIF 0.0036
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0032
5682 Ribonuclease pancreatic RNASE1 0.0031
822 Aldose reductase AKR1B1 0.0029
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0027
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0024
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