DT-Web

DB03502 - (4s)-4-{[(2s)-2-Amino-3-Oxopropyl]Sulfanyl}-L-Homoserinate


Identification
Name (4s)-4-{[(2s)-2-Amino-3-Oxopropyl]Sulfanyl}-L-Homoserinate
Accession Number DB03502 (EXPT01789)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 222.262
Groups experimental
Monoisotopic Weight 222.067427636
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Aspartate-semialdehyde dehydrogenase
Name Aspartate-semialdehyde dehydrogenase
Gene Name asd
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.3448

Predictions


Id Partner name Gene Name Score
5333 Alcohol dehydrogenase, iron-containing TM_0920 0.0122
3772 3-oxoacyl-[acyl-carrier-protein] reductase fabG 0.0122
5326 Oxidoreductase, short chain dehydrogenase/reductase family TM_0441 0.0122
5157 Dehydrogenase/reductase SDR family member 11 DHRS11 0.0122
5346 Oxidoreductase, aldo/keto reductase family TM_1009 0.0122
5332 MtdA bifunctional protein mtdA 0.0122
5322 Oxidoreductase ydhF ydhF 0.0122
4403 Protein iolS iolS 0.0122
5330 General stress protein 69 yhdN 0.0122
5342 NADH-dependent butanol dehydrogenase, putative TM_0820 0.0122
3778 NAD(P) transhydrogenase subunit beta pntB 0.0122
5343 NADP-dependent fatty aldehyde dehydrogenase aldH 0.0122
729 GDP-L-fucose synthetase TSTA3 0.0106
3463 GDP-L-fucose synthetase fcl 0.0106
5328 Prostaglandin F synthase Tb11.02.2310 0.0106
4582 Putative pteridine reductase 2 ptr2 0.0106
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0106
2375 ADP-L-glycero-D-manno-heptose-6-epimerase hldD 0.0106
2636 Shikimate dehydrogenase aroE 0.0106
3515 Shikimate dehydrogenase aroE 0.0106
3446 NADP-dependent alcohol dehydrogenase adh 0.0106
989 L-xylulose reductase DCXR 0.0106
5073 Ferredoxin--NADP reductase petH 0.0106
5076 Ferredoxin--NADP reductase fpr 0.0106
5119 Ferredoxin--NADP reductase petH 0.0106
5121 Ferredoxin--NADP reductase fpr 0.0106
2286 Isocitrate dehydrogenase [NADP] icd 0.0106
2302 Isocitrate dehydrogenase [NADP] icd 0.0106
2771 Isocitrate dehydrogenase [NADP] icd 0.0106
4628 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase gapN 0.0106
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.0106
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.0106
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0106
2305 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 0.0106
6862 Aldo-keto reductase family 1 member B10 AKR1B10 0.0098
6297 Prostaglandin reductase 1 PTGR1 0.0098
4531 Putative ketoacyl reductase actIII 0.0098
1124 Sepiapterin reductase SPR 0.0092
2675 Pteridine reductase 1 PTR1 0.0092
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.0092
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0092
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.0089
666 NADP-dependent malic enzyme ME1 0.0089
646 Malate dehydrogenase, cytoplasmic MDH1 0.0087
11 NAD(P) transhydrogenase, mitochondrial NNT 0.0087
2159 Quinone oxidoreductase CRYZ 0.0085
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0076
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0076
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0076
654 Flavin reductase BLVRB 0.0075
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.007
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0069
444 Alcohol dehydrogenase 1B ADH1B 0.0068
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0066
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0066
76 Nitric-oxide synthase, brain NOS1 0.0062
822 Aldose reductase AKR1B1 0.0061
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0057
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0057
365 Dihydrofolate reductase DHFR 0.0057
2381 Dihydrofolate reductase DFR1 0.0057
2833 Dihydrofolate reductase Not Available 0.0057
2931 Dihydrofolate reductase folA 0.0057
3544 Dihydrofolate reductase folA 0.0057
3682 Dihydrofolate reductase folA 0.0057
6642 Dihydrofolate reductase folA 0.0057
6756 Dihydrofolate reductase dfrA 0.0057
4120 NADPH--cytochrome P450 reductase POR 0.0054
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