Identification
Name 8-Demethyl-8-Dimethylamino-Flavin-Adenine-Dinucleotide
Accession Number DB03482 (EXPT02776)
Type small molecule
Description Not Available
Structure
Categories (*)
Molecular Weight 814.591
Groups experimental
Monoisotopic Weight 814.183683556
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available
P-hydroxybenzoate hydroxylase
Name P-hydroxybenzoate hydroxylase
Gene Name pobA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.5041
Id Partner name Gene Name Score
2769 P-hydroxybenzoate hydroxylase pobA 0.5041
2741 Chorismate--pyruvate lyase ubiC 0.1024
4404 FcbC1 protein fcbC 0.0891
5095 Putidaredoxin reductase camA 0.0059
5122 Mersacidin decarboxylase mrsD 0.0059
3763 5,10-methylenetetrahydrofolate reductase metF 0.0059
3918 5,10-methylenetetrahydrofolate reductase MTHFR 0.0059
5094 5,10-methylenetetrahydrofolate reductase metF 0.0059
5097 PROBABLE DIHYDROLIPOAMIDE DEHYDROGENASE LPDA lpdA 0.0059
526 Thioredoxin reductase trxB 0.0059
3767 Thioredoxin reductase trxB 0.0059
5078 Amine oxidase, flavin-containing PSPTO1126 0.0059
5112 Benzoate 1,2-dioxygenase electron transfer component benC 0.0059
5115 FkbI fkbI 0.0059
5109 Outer membrane protein p64k or PM-6 m-6 0.0059
5114 Putative acyl-CoA dehydrogenase TT_C0779 0.0059
1329 Apoptosis-inducing factor 1, mitochondrial AIFM1 0.0059
5111 Phenylacetone monooxygenase pamO 0.0059
5083 Cryptochrome DASH cry 0.0059
5100 Gamma-aminobutyrate metabolism dehydratase/isomerase abfD 0.0059
5107 Alkyl hydroperoxide reductase subunit F ahpF 0.0059
5118 Alkyl hydroperoxide reductase subunit F ahpF 0.0059
5102 4-cresol dehydrogenase [hydroxylating] flavoprotein subunit pchF 0.0059
5081 L-aspartate oxidase nadB 0.0059
1410 Oxidoreductase HSD17B6 0.0059
4725 Oxidoreductase Not Available 0.0059
5124 Oxidoreductase Not Available 0.0059
3133 UDP-galactopyranose mutase glf 0.0059
5099 UDP-galactopyranose mutase glf 0.0059
4486 Phenol 2-hydroxylase component B pheA2 0.0051
3594 Deoxyribodipyrimidine photo-lyase phr 0.0051
5079 Deoxyribodipyrimidine photo-lyase phrB 0.0051
5080 Deoxyribodipyrimidine photo-lyase phr 0.0051
2526 NADPH-ferredoxin reductase fprA fprA 0.0051
5003 Acyl-CoA dehydrogenase, short-chain specific Not Available 0.0051
4439 Ferredoxin reductase bphA4 0.0051
667 Acyl-CoA dehydrogenase family member 8, mitochondrial ACAD8 0.0051
6639 Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 0.0051
440 Isovaleryl-CoA dehydrogenase, mitochondrial IVD 0.0051
3506 Glutaryl-CoA dehydrogenase, mitochondrial GCDH 0.0051
5073 Ferredoxin--NADP reductase petH 0.0051
5076 Ferredoxin--NADP reductase fpr 0.0051
5119 Ferredoxin--NADP reductase petH 0.0051
5121 Ferredoxin--NADP reductase fpr 0.0051
4477 Dihydrolipoyl dehydrogenase lpdV 0.0051
5077 Dihydrolipoyl dehydrogenase Not Available 0.0051
5117 Dihydrolipoyl dehydrogenase lpd 0.0051
3247 2-oxopropyl-CoM reductase, carboxylating xecC 0.0051
5072 N,N-dimethylglycine oxidase dmg 0.0051
2268 Cholesterol oxidase choB 0.0051
2822 Cholesterol oxidase choA 0.0051
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0051
2470 Pyruvate oxidase pox5 0.0051
5091 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0051
5093 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0051
2893 Glycine oxidase thiO 0.0047
3102 Flavohemoprotein hmp 0.0047
4969 Flavohemoprotein hmp 0.0047
3185 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM 0.0047
4440 NADH peroxidase npr 0.0047
3254 Bifunctional protein putA [Includes: Proline dehydrogenase putA 0.0047
2567 Thymidylate synthase thyX thyX 0.0045
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0045
2823 Trypanothione reductase TPR 0.0045
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0042
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0042
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0042
126 D-lactate dehydrogenase dld 0.0042
3545 D-lactate dehydrogenase Not Available 0.0042
4510 D-lactate dehydrogenase ldhA 0.0042
327 Glutathione reductase gor 0.0042
5110 Glutathione reductase GR2 0.0042
2380 Monomeric sarcosine oxidase soxA 0.0041
605 Fumarate reductase flavoprotein subunit frdA 0.0041
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0041
3673 Fumarate reductase flavoprotein subunit fccA 0.0041
4912 Fumarate reductase flavoprotein subunit ifcA 0.0041
6549 Fumarate reductase flavoprotein subunit frdA 0.0041
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0039
6645 D-amino-acid oxidase DAO 0.0039
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0035
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0032
714 Glutathione reductase, mitochondrial GSR 0.0031
76 Nitric-oxide synthase, brain NOS1 0.003
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0028
4120 NADPH--cytochrome P450 reductase POR 0.0027
3939 Amine oxidase [flavin-containing] B MAOB 0.0024
3947 Xanthine dehydrogenase/oxidase XDH 0.0022
3941 Amine oxidase [flavin-containing] A MAOA 0.0021