DT-Web

DB03367 - PF-00356231


Identification
Name PF-00356231
Accession Number DB03367 (EXPT02553)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 428.503
Groups experimental
Monoisotopic Weight 428.119463206
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Macrophage metalloelastase
Name Macrophage metalloelastase
Gene Name MMP12
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.4154

Predictions


Id Partner name Gene Name Score
1167 Interstitial collagenase MMP1 0.068
370 Urease alpha subunit ureC 0.0676
6188 Stromelysin-2 MMP10 0.0404
6195 Matrix metalloproteinase-20 MMP20 0.0402
2970 Matrix metalloproteinase-16 MMP16 0.0336
6230 A disintegrin and metalloproteinase with thrombospondin motifs 5 ADAMTS5 0.0299
1926 Stromelysin-1 MMP3 0.0291
2154 Neutrophil collagenase MMP8 0.026
6374 Disintegrin and metalloproteinase domain-containing protein 28 ADAM28 0.0253
6190 Stromelysin-3 MMP11 0.006
6189 Matrilysin MMP7 0.0057
6200 Matrix metalloproteinase-26 MMP26 0.0056
6201 Matrix metalloproteinase-27 MMP27 0.0056
6198 Matrix metalloproteinase-24 MMP24 0.0056
6199 Matrix metalloproteinase-25 MMP25 0.0056
6191 Matrix metalloproteinase-14 MMP14 0.0056
6194 Matrix metalloproteinase-19 MMP19 0.0056
6192 Matrix metalloproteinase-15 MMP15 0.0056
6197 Matrix metalloproteinase-23 MMP23A 0.0056
6196 Matrix metalloproteinase-21 MMP21 0.0056
6202 Matrix metalloproteinase-28 MMP28 0.0056
6193 Matrix metalloproteinase-17 MMP17 0.0056
1330 Collagenase 3 MMP13 0.0047
707 72 kDa type IV collagenase MMP2 0.0045
65 Matrix metalloproteinase-9 Not Available 0.0044
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