DT-Web

DB03316 - 1,4-Diethylene Dioxide


Identification
Name 1,4-Diethylene Dioxide
Accession Number DB03316 (EXPT01208)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 88.1051
Groups experimental
Monoisotopic Weight 88.0524295
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Subtilisin Carlsberg
Name Subtilisin Carlsberg
Gene Name apr
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 2.0125
Tumor necrosis factor ligand superfamily member 13B
Name Tumor necrosis factor ligand superfamily member 13B
Gene Name TNFSF13B
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.4635
Epsin-1
Name Epsin-1
Gene Name EPN1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Structural polyprotein
Name Structural polyprotein
Gene Name Not Available
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.0376
Transforming growth factor beta-3
Name Transforming growth factor beta-3
Gene Name TGFB3
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available

Predictions


Id Partner name Gene Name Score
3628 Structural polyprotein Not Available 1.0376
4892 Structural polyprotein Not Available 1.0376
4533 Glyoxalase family protein BC_1747 0.0169
3583 6-phosphogluconolactonase pgl 0.0155
5591 Complement component C8 gamma chain C8G 0.0111
5577 N5-carboxyaminoimidazole ribonucleotide mutase purE 0.0111
2300 Lysozyme E 0.0111
3633 Lysozyme R 0.0111
5597 Lysozyme 17 0.0111
5582 Regulator of transcription; stringent starvation protein A sspA 0.0111
2838 Ribose-5-phosphate isomerase A rpiA 0.0111
2952 Ribose-5-phosphate isomerase A rpiA 0.0111
5595 Ribose-5-phosphate isomerase A rpiA 0.0111
5598 Glycerol uptake operon antiterminator-related protein TM_1436 0.0111
4238 50S ribosomal protein L4 rplD 0.0111
5578 50S ribosomal protein L4 rplD 0.0111
6173 50S ribosomal protein L4 rplD 0.0111
6219 50S ribosomal protein L4 rplD 0.0111
4695 UPF0124 protein yfiH yfiH 0.0111
5590 N utilization substance protein B homolog nusB 0.0111
5588 Cell division protein FtsY TM_0570 0.0111
5592 Ribonucleoside-diphosphate reductase subunit beta nrdF 0.0111
5587 Iron(III)-binding periplasmic protein fbpA 0.0111
5583 RNA 3'-terminal phosphate cyclase rtcA 0.0111
5600 Pyruvate decarboxylase pdc 0.0111
3792 KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase eda 0.0111
5593 Transferase Not Available 0.0111
5581 Beta-fructosidase bfrA 0.0111
5060 Intron-associated endonuclease 1 ITEVIR 0.0111
4375 Glutamine synthetase 1 glnA1 0.0111
5575 Short tail fiber protein 12 0.011
5574 Invasin YPTB1668 0.011
5586 Pleckstrin homology domain-containing family A member 1 PLEKHA1 0.011
5580 Hexon protein PII 0.011
5682 Ribonuclease pancreatic RNASE1 0.0097
4992 Cytochrome c peroxidase Not Available 0.0096
5006 RNASE4 protein RNASE4 0.0096
3132 Tryptophan synthase alpha chain trpA 0.0096
6568 Tryptophan synthase alpha chain trpA 0.0096
5328 Prostaglandin F synthase Tb11.02.2310 0.0096
5599 3-carboxy-cis,cis-muconate cycloisomerase pcaB 0.0096
3085 Molybdopterin-guanine dinucleotide biosynthesis protein A mobA 0.0096
3729 Citrate synthase gltA 0.0096
4575 Citrate synthase cit 0.0096
4580 Citrate synthase gltA 0.0096
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0096
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0096
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0096
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0096
2555 Pol polyprotein pol 0.0096
3242 Pol polyprotein gag-pol 0.0096
3471 Pol polyprotein gag-pro-pol 0.0096
5256 Pol polyprotein pol 0.0096
6469 Pol polyprotein gag-pol 0.0096
6565 Pol polyprotein Not Available 0.0096
2149 Angiogenin ANG 0.0089
2521 Cell division protein ftsZ ftsZ 0.0089
3301 Cell division protein ftsZ ftsZ 0.0089
2603 Beta-lactamase II blm 0.0089
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0089
2869 1-deoxy-D-xylulose 5-phosphate reductoisomerase dxr 0.0084
3486 Fumarate hydratase class II fumC 0.0084
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0084
2942 Sialidase nanH 0.0084
3546 Sialidase nedA 0.0084
2286 Isocitrate dehydrogenase [NADP] icd 0.0084
2302 Isocitrate dehydrogenase [NADP] icd 0.0084
2771 Isocitrate dehydrogenase [NADP] icd 0.0084
857 Malate dehydrogenase, mitochondrial MDH2 0.0083
4037 Hypothetical protein GPX1 0.0083
4297 Hypothetical protein SP_1951 0.0083
4521 Hypothetical protein BC_2969 0.0083
4540 Hypothetical protein TM_1070 0.0083
4555 Hypothetical protein MT1739 0.0083
4569 Hypothetical protein mshD 0.0083
4578 Hypothetical protein PA3270 0.0083
4747 Hypothetical protein PA3967 0.0083
5177 Hypothetical protein TM_0096 0.0083
5194 Hypothetical protein PA1204 0.0083
5240 Hypothetical protein Rv2991 0.0083
5370 Hypothetical protein TM_1158 0.0083
5710 Hypothetical protein Tb927.5.1360 0.0083
4527 Putative hydrolase ycdX ycdX 0.0083
4536 Transcriptional regulator, IclR family TM_0065 0.0083
4545 Molybdopterin-converting factor subunit 2 moaE 0.0083
4514 Citrate lyase beta subunit-like protein citE 0.0083
4781 Citrate lyase beta subunit-like protein DR_1240 0.0083
4522 Arginine N-succinyltransferase subunit alpha astA 0.0083
4547 Iron binding protein FbpA fbpA 0.0083
4106 Guanylate kinase GUK1 0.0083
4516 Guanylate kinase gmk 0.0083
4538 Hypothetical protein VC1899 VC_1899 0.0083
4529 Oxalate decarboxylase oxdC oxdC 0.0083
4546 Aminotransferase, putative TM_1131 0.0083
658 Para-aminobenzoate synthase component 1 pabB 0.0083
2501 Protein ygbM ygbM 0.0083
4526 Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein TM_1223 0.0083
4524 Mannose-6-phosphate isomerase yvyI 0.0083
4535 Glutaconyl-CoA decarboxylase subunit alpha gcdA 0.0083
4548 Gyrase B gyrB 0.0083
4515 Peripheral plasma membrane protein CASK CASK 0.0083
941 Betaine--homocysteine S-methyltransferase 1 BHMT 0.0082
332 Beta-lactamase blaZ 0.0081
2478 Beta-lactamase ampC 0.0081
2613 Beta-lactamase ampC 0.0081
2635 Beta-lactamase ampC 0.0081
2700 Beta-lactamase penP 0.0081
5445 Beta-lactamase blaB 0.0081
6019 Beta-lactamase SHV-7 0.0081
6701 Beta-lactamase cphA 0.0081
1123 Eosinophil cationic protein RNASE3 0.0081
2805 Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 HS3ST3A1 0.008
2452 Tryptophanyl-tRNA synthetase trpS 0.0078
2697 Uridine-cytidine kinase 2 UCK2 0.0077
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0077
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0077
411 Glycine N-methyltransferase GNMT 0.0073
5579 Carboxypeptidase B CPB1 0.0073
2929 (S)-2-haloacid dehalogenase dhlB 0.0072
2995 (S)-2-haloacid dehalogenase Not Available 0.0072
3237 Beta-lactamase OXA-2 bla 0.0072
3261 Signal recognition particle protein ffh 0.0072
4542 Glutaminase 1 glsA1 0.0072
4544 Glutaminase 1 glsA1 0.0072
56 Delta-aminolevulinic acid dehydratase ALAD 0.0072
2356 Delta-aminolevulinic acid dehydratase hemB 0.0072
3613 Delta-aminolevulinic acid dehydratase hemB 0.0072
3674 Delta-aminolevulinic acid dehydratase hemB 0.0072
4496 C-terminal-binding protein 1 CTBP1 0.0072
4528 Phenazine biosynthesis protein PhzD phzD1 0.0072
3759 Glutathione S-transferase gst 0.0072
4541 Glutathione S-transferase GST 0.0072
4517 Probable butyrate kinase 2 buk2 0.0072
4532 Gephyrin GPHN 0.0072
3478 Glucose-1-phosphate thymidylyltransferase rmlA 0.0072
4277 Glucose-1-phosphate thymidylyltransferase rmlA 0.0072
3384 Macrophage migration inhibitory factor MIF 0.0071
128 Adenine phosphoribosyltransferase APRT 0.0067
3467 Methylglyoxal synthase mgsA 0.0067
2775 Dihydroorotate dehydrogenase pyrD 0.0067
4531 Putative ketoacyl reductase actIII 0.0067
2230 Catalase CAT 0.0067
3249 Catalase katA 0.0067
3625 Catalase katA 0.0067
4539 Catalase katA 0.0067
4941 Catalase katB 0.0067
2525 3-phosphoshikimate 1-carboxyvinyltransferase aroA 0.0063
3201 3-phosphoshikimate 1-carboxyvinyltransferase aroA 0.0063
2688 Peptide deformylase def 0.006
2708 Peptide deformylase def 0.006
3004 Peptide deformylase def 0.006
4337 Peptide deformylase def 0.006
4338 Peptide deformylase def 0.006
5368 Peptide deformylase def 0.006
5371 Peptide deformylase def 0.006
6375 Peptide deformylase def 0.006
6378 Peptide deformylase def 0.006
6379 Peptide deformylase def 0.006
6776 Peptide deformylase def 0.006
6900 Peptide deformylase def 0.006
4534 Cytohesin-2 CYTH2 0.006
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0058
4269 Hypoxanthine-guanine phosphoribosyltransferase, putative HGPRTase 0.0056
822 Aldose reductase AKR1B1 0.0055
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0052
760 Fibroblast growth factor 1 FGF1 0.0049
3027 Streptavidin Not Available 0.0048
810 Heme oxygenase 1 HMOX1 0.0048
3391 Heme oxygenase 1 pbsA1 0.0048
500 Monocarboxylate transporter 4 SLC16A3 0.0046
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0045
76 Nitric-oxide synthase, brain NOS1 0.0042
357 Carbonic anhydrase 2 CA2 0.0031
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