DT-Web

DB03313 - Cephalosporin C


Identification
Name Cephalosporin C
Accession Number DB03313 (EXPT01031)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 416.426
Groups experimental
Monoisotopic Weight 416.112760385
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


D-alanyl-D-alanine carboxypeptidase
Name D-alanyl-D-alanine carboxypeptidase
Gene Name Not Available
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.5767
Penicillin-binding protein 1b
Name Penicillin-binding protein 1b
Gene Name pbp1b
Pharmacological action yes
Actions inhibitor
References
  • Williamson R, Hakenbeck R, Tomasz A: In vivo interaction of beta-lactam antibiotics with the penicillin-binding proteins of Streptococcus pneumoniae. Antimicrob Agents Chemother. 1980 Oct;18(4):629-37. - Pubmed
DTHybrid score 0.0305
Penicillin-binding protein 1A
Name Penicillin-binding protein 1A
Gene Name pbpA
Pharmacological action yes
Actions inhibitor
References
  • Williamson R, Hakenbeck R, Tomasz A: In vivo interaction of beta-lactam antibiotics with the penicillin-binding proteins of Streptococcus pneumoniae. Antimicrob Agents Chemother. 1980 Oct;18(4):629-37. - Pubmed
DTHybrid score 0.03
Penicillin-binding protein 2B
Name Penicillin-binding protein 2B
Gene Name penA
Pharmacological action yes
Actions inhibitor
References
  • Williamson R, Hakenbeck R, Tomasz A: In vivo interaction of beta-lactam antibiotics with the penicillin-binding proteins of Streptococcus pneumoniae. Antimicrob Agents Chemother. 1980 Oct;18(4):629-37. - Pubmed
DTHybrid score 0.7466
Penicillin-binding protein 2a
Name Penicillin-binding protein 2a
Gene Name pbp2a
Pharmacological action yes
Actions inhibitor
References
  • Williamson R, Hakenbeck R, Tomasz A: In vivo interaction of beta-lactam antibiotics with the penicillin-binding proteins of Streptococcus pneumoniae. Antimicrob Agents Chemother. 1980 Oct;18(4):629-37. - Pubmed
DTHybrid score Not Available
Penicillin-binding protein 3
Name Penicillin-binding protein 3
Gene Name pbp3
Pharmacological action yes
Actions inhibitor
References
  • Williamson R, Hakenbeck R, Tomasz A: In vivo interaction of beta-lactam antibiotics with the penicillin-binding proteins of Streptococcus pneumoniae. Antimicrob Agents Chemother. 1980 Oct;18(4):629-37. - Pubmed
DTHybrid score 0.0287

Predictions


Id Partner name Gene Name Score
5756 D-alanyl-D-alanine carboxypeptidase dac 1.5767
159 Penicillin-binding protein 2B penA 0.7466
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.2073
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.1975
3195 Beta-lactamase Toho-1 bla 0.122
1729 Solute carrier family 22 member 6 SLC22A6 0.1198
118 Organic cation/carnitine transporter 2 SLC22A5 0.1113
633 Penicillin-binding proteins 1A/1B pbpA 0.1058
6113 MecA PBP2' (penicillin binding protein 2') mecA 0.0796
6142 Solute carrier family 22 member 8 SLC22A8 0.0669
587 Serum albumin ALB 0.0467
2457 Bacillolysin nprS 0.0438
1024 Solute carrier family 22 member 11 SLC22A11 0.0418
4512 Cytochrome P450 3A4 CYP3A4 0.0409
332 Beta-lactamase blaZ 0.0406
2478 Beta-lactamase ampC 0.0406
2613 Beta-lactamase ampC 0.0406
2635 Beta-lactamase ampC 0.0406
2700 Beta-lactamase penP 0.0406
5445 Beta-lactamase blaB 0.0406
6019 Beta-lactamase SHV-7 0.0406
6701 Beta-lactamase cphA 0.0406
6143 Solute carrier family 22 member 7 SLC22A7 0.0335
543 Penicillin-binding protein 1B mrcB 0.0305
6186 Penicillin-binding protein 1B ponB 0.0305
6822 Penicillin-binding protein 1b pbp1b 0.0305
1 Peptidoglycan synthetase ftsI ftsI 0.0304
4155 Peptidoglycan synthetase ftsI ftsI 0.0304
645 Penicillin-binding protein 1A mrcA 0.03
5805 Penicillin-binding protein 1A ponA 0.03
6185 Penicillin-binding protein 1A mrcA 0.03
3760 Penicillin-binding protein 5 precursor dacA 0.0291
867 Penicillin-binding protein 3 pbpC 0.0287
6119 Penicillin-binding protein 3 pbp3 0.0287
7157 Penicillin-binding protein 3 LMHCC_2184 0.0287
7162 Penicillin-binding protein 3 pbpB 0.0287
7172 Penicillin-binding protein 3 pbp3 0.0287
6184 D-alanyl-D-alanine carboxypeptidase dacC dacC 0.0275
6151 Monocarboxylate transporter 10 SLC16A10 0.0267
819 Penicillin-binding protein 4 dacB 0.0258
738 Monocarboxylate transporter 1 SLC16A1 0.0238
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0198
4200 Cytochrome P450 1A2 CYP1A2 0.0193
6067 Penicillin binding protein 2a mecA 0.0162
3426 Glutamine synthetase glnA 0.0097
3987 Glutamine synthetase GLUL 0.0097
4119 Cytochrome P450 2D6 CYP2D6 0.0091
115 Penicillin-binding protein 2 mrdA 0.008
6069 Penicillin-binding protein 2 mrdA 0.008
6118 Penicillin-binding protein 2 penA 0.008
6187 Penicillin-binding protein 2 pbpA 0.008
6686 Penicillin-binding protein 2 pbp2 0.008
6939 Penicillin-binding protein 2 mrdA 0.008
7163 Penicillin-binding protein 2 pbpA 0.008
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