DT-Web

DB03034 - Dextrofloxacine


Identification
Name Dextrofloxacine
Accession Number DB03034 (EXPT03256)
Type small molecule
Description A synthetic fluoroquinolone (FLUOROQUINOLONES) antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION. [PubChem]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 361.3675
Groups experimental
Monoisotopic Weight 361.143784348
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Autolysin
Name Autolysin
Gene Name lytA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.9167

Predictions


Id Partner name Gene Name Score
4511 Truncated transposase Not Available 0.2809
6530 Pancreatic lipase-related protein 2 PNLIPRP2 0.1405
2427 Ferrichrome-iron receptor fhuA 0.0788
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0715
4411 DNA protection during starvation protein dps 0.0469
5424 Endonuclease VIII-like 1 NEIL1 0.0469
5423 UPF0010 protein HI1317 HI_1317 0.0468
3780 Lipoprotein nlpI precursor nlpI 0.0468
3164 Biotin synthase bioB 0.0408
3186 Soluble calcium-activated nucleotidase 1 CANT1 0.0407
3583 6-phosphogluconolactonase pgl 0.0376
3221 Cytochrome c4 cc4 0.0355
113 S-adenosylmethionine decarboxylase proenzyme AMD1 0.0321
2723 Cholera enterotoxin subunit B ctxB 0.0277
183 Vascular endothelial growth factor A VEGFA 0.0262
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