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DB02948 - Fosmidomycin


Identification
Name Fosmidomycin
Accession Number DB02948 (EXPT01469)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 183.0997
Groups experimental
Monoisotopic Weight 183.029658947
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


1-deoxy-D-xylulose 5-phosphate reductoisomerase
Name 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Gene Name dxr
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.2578

Predictions


Id Partner name Gene Name Score
2803 Pyridoxine 5'-phosphate synthase pdxJ 0.2256
3792 KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase eda 0.0088
5590 N utilization substance protein B homolog nusB 0.0088
5598 Glycerol uptake operon antiterminator-related protein TM_1436 0.0088
5577 N5-carboxyaminoimidazole ribonucleotide mutase purE 0.0088
5591 Complement component C8 gamma chain C8G 0.0088
5582 Regulator of transcription; stringent starvation protein A sspA 0.0088
2838 Ribose-5-phosphate isomerase A rpiA 0.0088
2952 Ribose-5-phosphate isomerase A rpiA 0.0088
5595 Ribose-5-phosphate isomerase A rpiA 0.0088
5588 Cell division protein FtsY TM_0570 0.0088
4695 UPF0124 protein yfiH yfiH 0.0088
5592 Ribonucleoside-diphosphate reductase subunit beta nrdF 0.0088
2300 Lysozyme E 0.0088
3633 Lysozyme R 0.0088
5597 Lysozyme 17 0.0088
5587 Iron(III)-binding periplasmic protein fbpA 0.0088
5583 RNA 3'-terminal phosphate cyclase rtcA 0.0088
5593 Transferase Not Available 0.0088
4238 50S ribosomal protein L4 rplD 0.0088
5578 50S ribosomal protein L4 rplD 0.0088
6173 50S ribosomal protein L4 rplD 0.0088
6219 50S ribosomal protein L4 rplD 0.0088
5060 Intron-associated endonuclease 1 ITEVIR 0.0088
4375 Glutamine synthetase 1 glnA1 0.0088
5575 Short tail fiber protein 12 0.0088
5600 Pyruvate decarboxylase pdc 0.0088
5586 Pleckstrin homology domain-containing family A member 1 PLEKHA1 0.0088
5581 Beta-fructosidase bfrA 0.0088
5580 Hexon protein PII 0.0088
5574 Invasin YPTB1668 0.0088
5006 RNASE4 protein RNASE4 0.0077
3085 Molybdopterin-guanine dinucleotide biosynthesis protein A mobA 0.0076
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0076
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0076
4533 Glyoxalase family protein BC_1747 0.0076
3132 Tryptophan synthase alpha chain trpA 0.0076
6568 Tryptophan synthase alpha chain trpA 0.0076
5328 Prostaglandin F synthase Tb11.02.2310 0.0076
4992 Cytochrome c peroxidase Not Available 0.0076
3729 Citrate synthase gltA 0.0076
4575 Citrate synthase cit 0.0076
4580 Citrate synthase gltA 0.0076
5599 3-carboxy-cis,cis-muconate cycloisomerase pcaB 0.0076
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0076
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0076
2555 Pol polyprotein pol 0.0076
3242 Pol polyprotein gag-pol 0.0076
3471 Pol polyprotein gag-pro-pol 0.0076
5256 Pol polyprotein pol 0.0076
6469 Pol polyprotein gag-pol 0.0076
6565 Pol polyprotein Not Available 0.0076
2149 Angiogenin ANG 0.0071
1467 Tumor necrosis factor ligand superfamily member 13B TNFSF13B 0.007
2521 Cell division protein ftsZ ftsZ 0.007
3301 Cell division protein ftsZ ftsZ 0.007
3583 6-phosphogluconolactonase pgl 0.007
2603 Beta-lactamase II blm 0.007
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.007
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0067
2286 Isocitrate dehydrogenase [NADP] icd 0.0067
2302 Isocitrate dehydrogenase [NADP] icd 0.0067
2771 Isocitrate dehydrogenase [NADP] icd 0.0067
3486 Fumarate hydratase class II fumC 0.0067
2942 Sialidase nanH 0.0066
3546 Sialidase nedA 0.0066
2805 Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 HS3ST3A1 0.0064
941 Betaine--homocysteine S-methyltransferase 1 BHMT 0.0062
857 Malate dehydrogenase, mitochondrial MDH2 0.0062
2697 Uridine-cytidine kinase 2 UCK2 0.0061
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0061
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0061
1123 Eosinophil cationic protein RNASE3 0.0061
332 Beta-lactamase blaZ 0.0061
2478 Beta-lactamase ampC 0.0061
2613 Beta-lactamase ampC 0.0061
2635 Beta-lactamase ampC 0.0061
2700 Beta-lactamase penP 0.0061
5445 Beta-lactamase blaB 0.0061
6019 Beta-lactamase SHV-7 0.0061
6701 Beta-lactamase cphA 0.0061
2452 Tryptophanyl-tRNA synthetase trpS 0.006
5579 Carboxypeptidase B CPB1 0.0058
3384 Macrophage migration inhibitory factor MIF 0.0057
3478 Glucose-1-phosphate thymidylyltransferase rmlA 0.0057
4277 Glucose-1-phosphate thymidylyltransferase rmlA 0.0057
411 Glycine N-methyltransferase GNMT 0.0054
128 Adenine phosphoribosyltransferase APRT 0.0049
5682 Ribonuclease pancreatic RNASE1 0.0044
822 Aldose reductase AKR1B1 0.0044
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0043
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0041
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0032
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