DT-Web

DB02917 - N-Hydroxy-4-(Methyl{[5-(2-Pyridinyl)-2-Thienyl]Sulfonyl}Amino)Benzamide


Identification
Name N-Hydroxy-4-(Methyl{[5-(2-Pyridinyl)-2-Thienyl]Sulfonyl}Amino)Benzamide
Accession Number DB02917 (EXPT02343)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 389.449
Groups experimental
Monoisotopic Weight 389.050397363
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Histone deacetylase 8
Name Histone deacetylase 8
Gene Name HDAC8
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.381

Predictions


Id Partner name Gene Name Score
4762 Acetoin utilization protein acuC1 0.1566
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.1197
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.1197
6005 Histone deacetylase 7a HDAC7 0.1196
2554 Peptidyl-prolyl cis-trans isomerase, mitochondrial PPIF 0.083
4123 Histone deacetylase 3 HDAC3 0.0601
4121 Histone deacetylase 1 HDAC1 0.0601
4124 Histone deacetylase 6 HDAC6 0.0598
4122 Histone deacetylase 2 HDAC2 0.0299
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