DT-Web

DB02900 - Alpha-D-Mannose-6-Phosphate


Identification
Name Alpha-D-Mannose-6-Phosphate
Accession Number DB02900 (EXPT02088)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 260.1358
Groups experimental
Monoisotopic Weight 260.029718526
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Phosphomannomutase/phosphoglucomutase
Name Phosphomannomutase/phosphoglucomutase
Gene Name algC
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.0027
Cation-independent mannose-6-phosphate receptor
Name Cation-independent mannose-6-phosphate receptor
Gene Name IGF2R
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.6985
Cation-dependent mannose-6-phosphate receptor
Name Cation-dependent mannose-6-phosphate receptor
Gene Name M6PR
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available

Predictions


Id Partner name Gene Name Score
1350 Insulin-like growth factor-binding protein 3 IGFBP3 0.1767
958 Insulin-like growth factor 1 receptor IGF1R 0.1207
36 Insulin receptor INSR 0.1093
3101 Glucose-1-phosphatase agp 0.0939
1152 Glycogen phosphorylase, muscle form PYGM 0.0782
3091 Maltodextrin phosphorylase malP 0.0754
3478 Glucose-1-phosphate thymidylyltransferase rmlA 0.061
4277 Glucose-1-phosphate thymidylyltransferase rmlA 0.061
2538 6-phospho-beta-glucosidase bglT bglT 0.0455
2393 Maltose-6'-phosphate glucosidase glvA 0.0454
2439 Alpha,alpha-trehalose-phosphate synthase [UDP-forming] otsA 0.0396
1881 Hexokinase-1 HK1 0.0395
2597 Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] glmS 0.0365
2206 Glucose-6-phosphate isomerase GPI 0.0344
3602 Anti-sigma F factor antagonist spoIIAA 0.0261
2514 Phosphocarrier protein HPr ptsH 0.0261
5689 Phosphocarrier protein HPr ptsH 0.0261
5686 Potassium voltage-gated channel subfamily C member 4 KCNC4 0.0261
822 Aldose reductase AKR1B1 0.0259
1130 Lithostathine 1 alpha REG1A 0.0227
4542 Glutaminase 1 glsA1 0.0227
4544 Glutaminase 1 glsA1 0.0227
3119 Fimbrial protein pilE1 0.021
2530 Protein kinase C theta type PRKCQ 0.021
4318 Siroheme synthase cysG 0.021
2207 Rhodopsin RHO 0.0207
3453 Alkaline phosphatase phoA 0.0198
5150 Endo-1,4-beta-xylanase Y xynY 0.0189
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0151
10 Glycogen phosphorylase, liver form PYGL 0.0149
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0146
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.014
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0123
4878 Glycoprotein hormones alpha chain CGA 0.0107
4871 Endo-beta-N-acetylglucosaminidase F3 endOF3 0.0107
1052 Cytotoxic T-lymphocyte protein 4 CTLA4 0.0107
1072 Granzyme B GZMB 0.0107
4880 Membrane cofactor protein CD46 0.0107
4877 Beta-mannanase man 0.0107
4869 Major capsid protein A430L 0.0107
4845 ADAM 33 ADAM33 0.0107
1563 Platelet glycoprotein Ib alpha chain GP1BA 0.0107
4850 Beta-2-glycoprotein 1 APOH 0.0107
757 Fusion glycoprotein F0 F 0.0107
4875 Fusion glycoprotein F0 F 0.0107
4852 Reticulon-4 receptor RTN4R 0.0107
4856 CD209 antigen CD209 0.0107
4889 Ig epsilon chain C region IGHE 0.0107
4189 Alpha-galactosidase A GLA 0.0107
4882 Dipeptidyl aminopeptidase-like protein 6 DPP6 0.0107
4721 Beta-1,4-mannanase manA 0.0107
1354 Beta-glucuronidase GUSB 0.0107
442 Envelope glycoprotein gp41 0.0107
4859 Envelope glycoprotein env 0.0107
3352 Structural polyprotein Not Available 0.0107
3628 Structural polyprotein Not Available 0.0107
4892 Structural polyprotein Not Available 0.0107
6858 Inactive carboxylesterase 4 CES1P1 0.0093
1184 Interferon beta IFNB1 0.0093
4857 Zinc-alpha-2-glycoprotein AZGP1 0.0093
1379 Interleukin-12 subunit beta IL12B 0.0093
793 T-cell surface antigen CD2 CD2 0.0093
4890 Hemagglutinin HA 0.0093
6566 Hemagglutinin Not Available 0.0093
4861 Interleukin-6 receptor alpha chain IL6R 0.0093
119 Carcinoembryonic antigen-related cell adhesion molecule 1 CEACAM1 0.0093
4193 Atrial natriuretic peptide clearance receptor NPR3 0.0093
3837 Cytokine receptor common beta chain CSF2RB 0.0093
554 Low-density lipoprotein receptor LDLR 0.0087
3444 Cyanovirin-N Not Available 0.0086
2998 Sialic acid-binding Ig-like lectin 7 SIGLEC7 0.0086
3258 Mannosyl-oligosaccharide alpha-1,2-mannosidase MSDC 0.0086
1859 Prostatic acid phosphatase ACPP 0.0086
3140 Hemagglutinin-neuraminidase HN 0.0086
3609 Hemagglutinin-neuraminidase HN 0.0086
2297 Genome polyprotein Not Available 0.0086
2322 Genome polyprotein Not Available 0.0086
2694 Genome polyprotein Not Available 0.0086
2719 Genome polyprotein Not Available 0.0086
2860 Genome polyprotein Not Available 0.0086
2928 Genome polyprotein Not Available 0.0086
3160 Genome polyprotein Not Available 0.0086
3260 Genome polyprotein Not Available 0.0086
4783 Genome polyprotein Not Available 0.0086
5726 Genome polyprotein Not Available 0.0086
5779 Genome polyprotein Not Available 0.0086
5867 Genome polyprotein Not Available 0.0086
6253 Genome polyprotein Not Available 0.0086
6301 Genome polyprotein Not Available 0.0086
6380 Genome polyprotein Not Available 0.0086
6381 Genome polyprotein Not Available 0.0086
6437 Genome polyprotein Not Available 0.0086
6520 Genome polyprotein Not Available 0.0086
6521 Genome polyprotein Not Available 0.0086
6652 Genome polyprotein Not Available 0.0086
6734 Genome polyprotein Not Available 0.0086
6735 Genome polyprotein Not Available 0.0086
6736 Genome polyprotein Not Available 0.0086
6737 Genome polyprotein Not Available 0.0086
6738 Genome polyprotein Not Available 0.0086
6739 Genome polyprotein Not Available 0.0086
6744 Genome polyprotein Not Available 0.0086
6748 Genome polyprotein Not Available 0.0086
6894 Genome polyprotein Not Available 0.0086
6898 Genome polyprotein Not Available 0.0086
852 Heparin cofactor 2 SERPIND1 0.0083
18 High affinity immunoglobulin epsilon receptor subunit alpha FCER1A 0.0082
4666 Fucose-binding lectin PA-IIL lecB 0.0081
2372 Bifunctional tail protein 9 0.0081
4787 Envelope glycoprotein gp160 env 0.0081
4820 Envelope glycoprotein gp160 env 0.0081
5727 Envelope glycoprotein gp160 env 0.0081
2577 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase MAN1B1 0.0078
3480 Mannan endo-1,4-beta-mannosidase manA 0.0075
64 Neuraminidase NA 0.0075
641 Neuraminidase NA 0.0075
2676 Neuraminidase NA 0.0075
3026 Neuraminidase NA 0.0075
3519 Neuraminidase NA 0.0075
6007 Neuraminidase NA 0.0075
595 Fibrinogen alpha chain FGA 0.0073
1439 Lactotransferrin LTF 0.0073
1782 Neutrophil gelatinase-associated lipocalin LCN2 0.0071
1243 Cathepsin D CTSD 0.0071
2430 Chondroitinase B cslB 0.0069
6307 Ig gamma-2 chain C region IGHG2 0.0068
2581 Chondroitinase AC cslA 0.0068
6847 Lactase-phlorizin hydrolase LCT 0.0067
6500 Phospholipase A2 PLA2G1B 0.0065
309 Antithrombin-III SERPINC1 0.0064
3814 Complement C1r subcomponent C1R 0.0059
4785 Ig gamma-1 chain C region IGHG1 0.0056
76 Nitric-oxide synthase, brain NOS1 0.0055
4604 Liver carboxylesterase 1 CES1 0.0053
952 Dipeptidyl peptidase 4 DPP4 0.0048
3923 Cholinesterase BCHE 0.0042
20 Prostaglandin G/H synthase 1 PTGS1 0.0038
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