DT-Web

DB02823 - Phosphonoacetic Acid


Identification
Name Phosphonoacetic Acid
Accession Number DB02823 (EXPT02488)
Type small molecule
Description A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent. [PubChem]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 140.0319
Groups experimental
Monoisotopic Weight 139.987459782
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Alkaline phosphatase
Name Alkaline phosphatase
Gene Name phoA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.5278

Predictions


Id Partner name Gene Name Score
2514 Phosphocarrier protein HPr ptsH 0.0312
5689 Phosphocarrier protein HPr ptsH 0.0312
3602 Anti-sigma F factor antagonist spoIIAA 0.0312
5686 Potassium voltage-gated channel subfamily C member 4 KCNC4 0.0312
1130 Lithostathine 1 alpha REG1A 0.0272
4542 Glutaminase 1 glsA1 0.0272
4544 Glutaminase 1 glsA1 0.0272
4318 Siroheme synthase cysG 0.0251
3119 Fimbrial protein pilE1 0.0251
2530 Protein kinase C theta type PRKCQ 0.025
2503 Phosphomannomutase/phosphoglucomutase algC 0.0226
5150 Endo-1,4-beta-xylanase Y xynY 0.0226
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0181
10 Glycogen phosphorylase, liver form PYGL 0.0176
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0176
2207 Rhodopsin RHO 0.0174
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0167
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0146
1152 Glycogen phosphorylase, muscle form PYGM 0.0142
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