DT-Web

DB02640 - Fumagillin


Identification
Name Fumagillin
Accession Number DB02640 (EXPT01509)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 460.5598
Groups experimental
Monoisotopic Weight 460.246103506
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Methionine aminopeptidase 2
Name Methionine aminopeptidase 2
Gene Name METAP2
Pharmacological action unknown
Actions ligand
References
  • Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. - Pubmed
DTHybrid score 1.5981

Predictions


Id Partner name Gene Name Score
4829 Transcriptional regulator, HTH_3 family VC_1968 0.0927
6621 Methionine aminopeptidase 1 METAP1 0.0609
2392 Biphenyl-2,3-diol 1,2-dioxygenase bphC 0.0252
3032 Biphenyl-2,3-diol 1,2-dioxygenase bphC 0.0252
2314 Triosephosphate isomerase TPI 0.0221
3417 Triosephosphate isomerase tpiA 0.0221
3443 Triosephosphate isomerase tpiA 0.0221
6346 Triosephosphate isomerase TPI1 0.0221
5682 Ribonuclease pancreatic RNASE1 0.0181
465 Calmodulin CALM1 0.0149
191 Peptide methionine sulfoxide reductase MSRA 0.0083
941 Betaine--homocysteine S-methyltransferase 1 BHMT 0.0082
480 Methionine-R-sulfoxide reductase B2 MSRB2 0.0077
317 Methionine-R-sulfoxide reductase SEPX1 0.0077
3921 Methionine adenosyltransferase 2 subunit beta MAT2B 0.0077
600 Methionyl-tRNA synthetase, cytoplasmic MARS 0.0077
3995 Methionyl-tRNA synthetase, mitochondrial MARS2 0.0077
3996 Betaine--homocysteine S-methyltransferase 2 BHMT2 0.0077
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.0072
334 S-adenosylmethionine synthetase isoform type-2 MAT2A 0.0065
840 Methionine synthase reductase, mitochondrial MTRR 0.0058
809 Methionine synthase MTR 0.0055
2935 Methionine synthase metH 0.0055
3426 Glutamine synthetase glnA 0.0053
3987 Glutamine synthetase GLUL 0.0053
3917 Methylenetetrahydrofolate reductase MTHFR 0.0047
6151 Monocarboxylate transporter 10 SLC16A10 0.0042
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