DT-Web

DB02371 - 2-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Ethanesulfonic Acid


Identification
Name 2-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Ethanesulfonic Acid
Accession Number DB02371 (EXPT02328)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 229.251
Groups experimental
Monoisotopic Weight 229.062007907
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Complement C1s subcomponent
Name Complement C1s subcomponent
Gene Name C1S
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.3218

Predictions


Id Partner name Gene Name Score
3815 Complement C1q subcomponent subunit A C1QA 0.108
3817 Complement C1q subcomponent subunit C C1QC 0.108
3816 Complement C1q subcomponent subunit B C1QB 0.108
3814 Complement C1r subcomponent C1R 0.1069
1102 Low affinity immunoglobulin gamma Fc region receptor III-B FCGR3B 0.1068
3818 Low affinity immunoglobulin gamma Fc region receptor III-A FCGR3A 0.1068
3819 Low affinity immunoglobulin gamma Fc region receptor II-a FCGR2A 0.1068
3821 Low affinity immunoglobulin gamma Fc region receptor II-c FCGR2C 0.1068
3820 Low affinity immunoglobulin gamma Fc region receptor II-b FCGR2B 0.1057
784 High affinity immunoglobulin gamma Fc receptor I FCGR1A 0.1043
75 B-lymphocyte antigen CD20 MS4A1 0.0335
844 Epidermal growth factor receptor EGFR 0.0232
777 Tumor necrosis factor TNF 0.0224
744 Myeloid cell surface antigen CD33 CD33 0.0208
1733 Vitronectin VTN 0.0179
5901 T-cell surface glycoprotein CD3 zeta chain CD247 0.0167
5900 T-cell surface glycoprotein CD3 gamma chain CD3G 0.0167
1269 Tumor necrosis factor receptor superfamily member 1B TNFRSF1B 0.0167
1789 Lymphotoxin-alpha LTA 0.0167
302 T-cell surface glycoprotein CD3 epsilon chain CD3E 0.0167
5899 T-cell surface glycoprotein CD3 delta chain CD3D 0.0167
488 Integrin alpha-IIb ITGA2B 0.0153
724 Interleukin-2 receptor alpha chain IL2RA 0.0146
717 Interleukin-2 receptor subunit beta IL2RB 0.0146
2039 Integrin beta-3 ITGB3 0.0134
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0128
3811 Cytochrome P450 19A1 CYP19A1 0.0082
290 Prostaglandin G/H synthase 2 PTGS2 0.0069
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