DT-Web

DB02129 - Dihydroorotic Acid


Identification
Name Dihydroorotic Acid
Accession Number DB02129 (EXPT01249)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 158.1121
Groups experimental
Monoisotopic Weight 158.03275669
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Dihydroorotase
Name Dihydroorotase
Gene Name pyrC
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.1263

Predictions


Id Partner name Gene Name Score
3680 Dihydroorotate dehydrogenase A pyrDA 0.0978
2775 Dihydroorotate dehydrogenase pyrD 0.0902
2794 Orotate phosphoribosyltransferase pyrE 0.0778
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0571
3230 Non-ATP-dependent L-selective hydantoinase lhyD 0.0296
4819 Hydrolase Not Available 0.0296
5249 Hydrolase Not Available 0.0296
5436 Hydrolase Not Available 0.0296
3168 Beta-lactamase OXA-1 bla 0.0296
3122 D-hydantoinase Not Available 0.0296
3145 D-hydantoinase hyuA 0.0296
3281 Isoaspartyl dipeptidase iadA 0.0258
3292 Alanine racemase, catabolic dadX 0.0257
3237 Beta-lactamase OXA-2 bla 0.0257
4264 Alpha-L-fucosidase, putative TM_0306 0.0257
2801 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase murE 0.0237
2983 Methylmalonyl-CoA carboxyltransferase 5S subunit Not Available 0.0237
4549 Endonuclease III HP_0602 0.0224
2717 Folylpolyglutamate synthase fgs 0.0214
2340 Beta-lactamase PSE-2 bla 0.0202
2796 Parathion hydrolase opd 0.02
6539 Parathion hydrolase opd 0.02
894 Alanine racemase alr 0.0195
2453 Alanine racemase alr 0.0195
2317 UDP-N-acetylmuramoylalanine--D-glutamate ligase murD 0.0191
2240 Cell division protein kinase 2 CDK2 0.0111
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