DT-Web

DB02106 - [3,5-Dibromo-4-(4-Hydroxy-3-Phenethylcarbamoyl-Phenoxy)-Phenyl]-Acetic Acid


Identification
Name [3,5-Dibromo-4-(4-Hydroxy-3-Phenethylcarbamoyl-Phenoxy)-Phenyl]-Acetic Acid
Accession Number DB02106 (EXPT00196)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 553.24
Groups experimental
Monoisotopic Weight 550.994298145
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Thyroid hormone receptor beta-1
Name Thyroid hormone receptor beta-1
Gene Name THRB
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.0148

Predictions


Id Partner name Gene Name Score
758 Thyroid hormone receptor alpha THRA 0.131
6369 Thyroid hormone receptor, alpha isoform 1 variant Not Available 0.1207
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0356
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0351
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0335
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0312
594 Thyroxine-binding globulin SERPINA7 0.0292
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0238
373 Transthyretin TTR 0.0183
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0166
563 Thyroid peroxidase TPO 0.0157
199 Monocarboxylate transporter 8 SLC16A2 0.0148
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0138
6141 Sodium/bile acid cotransporter SLC10A1 0.0126
587 Serum albumin ALB 0.0121
6151 Monocarboxylate transporter 10 SLC16A10 0.0107
1588 Multidrug resistance protein 1 ABCB1 0.0101
6142 Solute carrier family 22 member 8 SLC22A8 0.0087
4924 Cytochrome P450 2C8 CYP2C8 0.0072
4512 Cytochrome P450 3A4 CYP3A4 0.003
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