DT-Web

DB02058 - SU4984


Identification
Name SU4984
Accession Number DB02058 (EXPT02973)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 335.3996
Groups experimental
Monoisotopic Weight 335.163376931
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Fibroblast growth factor receptor 2
Name Fibroblast growth factor receptor 2
Gene Name FGFR2
Pharmacological action unknown
Actions Not Available
References
  • Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. - Pubmed
DTHybrid score 0.7421
Basic fibroblast growth factor receptor 1
Name Basic fibroblast growth factor receptor 1
Gene Name FGFR1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.1053

Predictions


Id Partner name Gene Name Score
2216 Fibroblast growth factor receptor 4 FGFR4 0.1361
3856 Fibroblast growth factor receptor 3 FGFR3 0.1272
1585 Basement membrane-specific heparan sulfate proteoglycan core protein HSPG2 0.1213
3852 Neuropilin-1 NRP1 0.1056
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0501
5787 Angiopoietin-1 receptor TEK 0.0461
504 Mast/stem cell growth factor receptor KIT 0.0419
407 Vascular endothelial growth factor receptor 2 KDR 0.04
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0393
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0337
165 FL cytokine receptor FLT3 0.031
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0303
5798 Mitogen-activated protein kinase 11 MAPK11 0.0282
26 Vascular endothelial growth factor receptor 3 FLT4 0.0269
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0264
6824 Tyrosine-protein kinase Lyn LYN 0.0264
32 Vascular endothelial growth factor receptor 1 FLT1 0.0263
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0243
228 Beta platelet-derived growth factor receptor PDGFRB 0.0236
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0236
4118 Cytochrome P450 3A5 CYP3A5 0.0217
936 Ephrin type-A receptor 2 EPHA2 0.0203
4924 Cytochrome P450 2C8 CYP2C8 0.0196
6016 Cytochrome P450 2C19 CYP2C19 0.0194
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0193
777 Tumor necrosis factor TNF 0.0191
1618 High affinity nerve growth factor receptor NTRK1 0.0186
4757 Cytochrome P450 2C9 CYP2C9 0.0186
1588 Multidrug resistance protein 1 ABCB1 0.0182
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0163
4512 Cytochrome P450 3A4 CYP3A4 0.0159
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0153
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0152
776 Bile salt export pump ABCB11 0.0123
4200 Cytochrome P450 1A2 CYP1A2 0.0121
290 Prostaglandin G/H synthase 2 PTGS2 0.0118
6030 Cytochrome P450 2B6 CYP2B6 0.0118
20 Prostaglandin G/H synthase 1 PTGS1 0.0112
4119 Cytochrome P450 2D6 CYP2D6 0.011
6024 Cytochrome P450 1A1 CYP1A1 0.0107
6013 Cytochrome P450 2E1 CYP2E1 0.0103
2164 Multidrug resistance-associated protein 4 ABCC4 0.0044
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0039
6107 Cytochrome P450 3A7 CYP3A7 0.0034
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