DT-Web

DB01904 - D-Xylitol


Identification
Name D-Xylitol
Accession Number DB01904 (EXPT03268)
Type small molecule
Description A five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group. It is as sweet as sucrose and used as a noncariogenic sweetener. [PubChem]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 152.1458
Groups experimental
Monoisotopic Weight 152.068473494
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Xylose isomerase
Name Xylose isomerase
Gene Name xylA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.9097
Xylose isomerase
Name Xylose isomerase
Gene Name xylA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.9097
Xylose isomerase
Name Xylose isomerase
Gene Name xylA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.9097
Xylose isomerase
Name Xylose isomerase
Gene Name xylA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.9097
Hyaluronate lyase
Name Hyaluronate lyase
Gene Name SP_0314
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.9736

Predictions


Id Partner name Gene Name Score
3172 Hyaluronate lyase hylB 0.9736
2248 Malate synthase G glcB 0.355
3190 Malate synthase G glcB 0.355
2581 Chondroitinase AC cslA 0.2325
5355 1-pyrroline-5-carboxylate dehydrogenase Not Available 0.1477
3668 Maltose-binding periplasmic protein precursor malE 0.1381
2440 Endoglucanase F celCCF 0.1306
2430 Chondroitinase B cslB 0.1166
4702 Alpha-glucuronidase glcA67A 0.0903
4792 Alpha-glucuronidase aguA 0.0903
3258 Mannosyl-oligosaccharide alpha-1,2-mannosidase MSDC 0.0872
5696 Alginate lyase aly 0.0844
2577 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase MAN1B1 0.0777
3289 Beta-glucosidase A bglA 0.0687
3298 Beta-glucosidase A bglA 0.0687
4416 Chondroitinase Not Available 0.068
3839 Phytanoyl-CoA dioxygenase, peroxisomal PHYH 0.0201
3954 Egl nine homolog 2 EGLN2 0.0189
3962 Egl nine homolog 3 EGLN3 0.0189
3948 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 ALKBH2 0.0189
3946 Hypothetical protein DKFZp686H15154 OGFOD2 0.0189
3956 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 ALKBH3 0.0189
189 Solute carrier family 23 member 1 SLC23A1 0.0189
3966 Putative HIF-prolyl hydroxylase PH-4 P4HTM 0.0189
3953 2-oxoglutarate and iron-dependent oxygenase domain containing 1 OGFOD1 0.0189
3935 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 PLOD2 0.0189
3958 Jumonji/ARID domain-containing protein 1D KDM5D 0.0189
3943 Peptidyl-glycine alpha-amidating monooxygenase PAM 0.0185
3960 Egl nine homolog 1 EGLN1 0.0185
6847 Lactase-phlorizin hydrolase LCT 0.0158
3964 Trimethyllysine dioxygenase, mitochondrial TMLHE 0.0154
3940 Gamma-butyrobetaine dioxygenase BBOX1 0.0154
97 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 PLOD1 0.0154
3938 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 PLOD3 0.0154
3949 Prolyl 3-hydroxylase 2 LEPREL1 0.014
3951 Prolyl 3-hydroxylase 3 LEPREL2 0.014
3945 Prolyl 3-hydroxylase 1 LEPRE1 0.014
67 Prolyl 4-hydroxylase subunit alpha-1 P4HA1 0.0129
153 Dopamine beta-hydroxylase DBH 0.0127
3689 Endoglucanase A celA 0.0105
5411 Slt-IIvB stxB2e 0.0105
5563 Galectin-2 LGALS2 0.0105
5565 Inorganic polyphosphate/ATP-glucomannokinase ppgmk 0.0105
5046 Ecotin eco 0.0105
5554 D-galactose-binding periplasmic protein mglB 0.0105
3741 D-galactose-binding periplasmic protein precursor mglB 0.0105
1875 Pulmonary surfactant-associated protein D SFTPD 0.0105
4668 Laminarinase TM_0024 0.0105
3009 Beta-glucanase Not Available 0.0105
3793 Aspartate ammonia-lyase aspA 0.0105
5562 Hexokinase Not Available 0.0105
5569 Endo-1,4-beta glucanase EngF engF 0.0105
5553 Endoglucanase E1 Acel_0614 0.0105
5559 Neopullulanase nplT 0.0105
5568 Endoglucanase C307 celC307 0.0104
4670 Cellulase B celB 0.0104
4667 BH0236 protein BH0236 0.0104
3744 Endoglucanase SS precursor celS 0.0104
4671 Endoglucanase C cenC 0.0104
5570 Endoglucanase E-4 celD 0.0104
1184 Interferon beta IFNB1 0.0092
4509 Acetoin(diacetyl) reductase budC 0.0092
5498 Maltoporin lamB 0.0091
5561 Maltoporin lamB 0.0091
1503 Galectin-7 LGALS7 0.0091
5416 Coat protein VP1 Not Available 0.0091
5056 Maltooligosyltrehalose trehalohydrolase, putative treZ 0.0091
5176 YtnJ moxC 0.009
2728 Glucan 1,4-alpha-maltotetraohydrolase amyP 0.009
4622 Amylase Not Available 0.009
2705 Dimethyl sulfoxide reductase dmsA 0.009
5247 Endo-1,4-beta-xylanase Not Available 0.009
5248 Endo-1,4-beta-xylanase xlnA 0.009
5250 Endo-1,4-beta-xylanase xyl 0.009
3525 ADP-ribose pyrophosphatase, mitochondrial NUDT9 0.009
4669 Endo-1,4-beta-xylanase A xynA 0.009
4715 Endo-1,4-beta-xylanase A xlnA 0.009
5560 Endo-1,4-beta-xylanase A xynA 0.009
3091 Maltodextrin phosphorylase malP 0.0083
3747 Cellulase B precursor celB 0.0083
3547 Enterotoxin type B entB 0.0083
4811 Amylosucrase ams 0.0083
2856 Glucosamine-6-phosphate isomerase GNPDA1 0.0083
4819 Hydrolase Not Available 0.0083
5249 Hydrolase Not Available 0.0083
5436 Hydrolase Not Available 0.0083
2324 Botulinum neurotoxin type B botB 0.0083
2606 Neopullulanase 2 tvaII 0.0083
2531 Alpha-amylase amyE 0.0083
2948 Alpha-amylase amy 0.0083
3169 Alpha-amylase Not Available 0.0083
2541 Neopullulanase 1 tvaI 0.0083
2564 Glucan 1,4-alpha-maltohexaosidase Not Available 0.0083
3153 Quinoprotein glucose dehydrogenase-B gdhB 0.0083
4666 Fucose-binding lectin PA-IIL lecB 0.008
2826 Glucose--fructose oxidoreductase gfo 0.0079
2372 Bifunctional tail protein 9 0.0079
1881 Hexokinase-1 HK1 0.0079
3365 Beta-amylase spoII 0.0079
4830 Aldose 1-epimerase galM 0.0078
3225 Shiga toxin B-chain stxB 0.0078
6614 Lactase-like protein LCTL 0.0075
2293 Cyclomaltodextrin glucanotransferase Not Available 0.0075
2508 Cyclomaltodextrin glucanotransferase cgt 0.0075
2523 Cyclomaltodextrin glucanotransferase cgt 0.0075
3207 Cyclomaltodextrin glucanotransferase amyA 0.0075
3030 Salivary alpha-amylase AMY1A 0.0075
1675 Glucokinase GCK 0.0075
4662 Glucokinase glk 0.0075
4272 POSSIBLE CELLULASE CELA1 celA1 0.0073
2802 Endoglucanase G celCCG 0.0073
4692 A/G-specific adenine glycosylase mutY 0.0073
2570 Tetanus toxin tetX 0.0072
2448 Exoglucanase/xylanase [Includes: Exoglucanase cex 0.0072
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0065
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0065
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0065
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0065
2252 Endoglucanase 5A cel5A 0.0063
2723 Cholera enterotoxin subunit B ctxB 0.0061
10 Glycogen phosphorylase, liver form PYGL 0.0058
2427 Ferrichrome-iron receptor fhuA 0.0058
4513 Pancreatic alpha-amylase AMY2A 0.0058
1152 Glycogen phosphorylase, muscle form PYGM 0.0047
20 Prostaglandin G/H synthase 1 PTGS1 0.0029
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