DT-Web

DB01877 - N-Hydroxy 1n(4-Methoxyphenyl)Sulfonyl-4-(Z,E-N-Methoxyimino)Pyrrolidine-2r-Carboxamide


Identification
Name N-Hydroxy 1n(4-Methoxyphenyl)Sulfonyl-4-(Z,E-N-Methoxyimino)Pyrrolidine-2r-Carboxamide
Accession Number DB01877 (EXPT02941)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 345.371
Groups experimental
Monoisotopic Weight 345.099456045
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Stromelysin-1
Name Stromelysin-1
Gene Name MMP3
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.6634

Predictions


Id Partner name Gene Name Score
1330 Collagenase 3 MMP13 0.1271
6188 Stromelysin-2 MMP10 0.0331
6195 Matrix metalloproteinase-20 MMP20 0.0303
2203 Macrophage metalloelastase MMP12 0.0232
2970 Matrix metalloproteinase-16 MMP16 0.0045
6190 Stromelysin-3 MMP11 0.0045
6189 Matrilysin MMP7 0.0043
6200 Matrix metalloproteinase-26 MMP26 0.0042
6201 Matrix metalloproteinase-27 MMP27 0.0041
6198 Matrix metalloproteinase-24 MMP24 0.0041
6197 Matrix metalloproteinase-23 MMP23A 0.0041
6191 Matrix metalloproteinase-14 MMP14 0.0041
6202 Matrix metalloproteinase-28 MMP28 0.0041
6192 Matrix metalloproteinase-15 MMP15 0.0041
6194 Matrix metalloproteinase-19 MMP19 0.0041
6196 Matrix metalloproteinase-21 MMP21 0.0041
6193 Matrix metalloproteinase-17 MMP17 0.0041
6199 Matrix metalloproteinase-25 MMP25 0.0041
1167 Interstitial collagenase MMP1 0.0041
2154 Neutrophil collagenase MMP8 0.0035
65 Matrix metalloproteinase-9 Not Available 0.0033
707 72 kDa type IV collagenase MMP2 0.0033
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