Pathway Substructures

160 Nodes of Interest
447 Sub-Structures

Analysis Description

Id
eaa7e2bb7c41711e538e8dec2e97b54c
Disease
Rectum adenocarcinoma Stage 4
Extraction p-value
1.0E-6
Enrichment p-value
0.05
Min number of nodes
5
Backward visit

Nodes of Interest

Id Details
10681 GNB5, GB5  
107 ADCY1, AC1, DFNB44  
108 ADCY2, AC2, HBAC2  
11059 WWP1, AIP5, Tiul1, hSDRP1  
111 ADCY5, AC5, FDFM  
1111 CHEK1, CHK1  
1129 CHRM2, HM2  
113 ADCY7, AC7  
114 ADCY8, AC8, ADCY3, HBAC1  
115 ADCY9, AC9  
1154 CISH, BACTS2, CIS, CIS-1, G18, SOCS  
117 ADCYAP1R1, PAC1, PAC1R, PACAPR, PACAPRI  
1236 CCR7, BLR2, CC-CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1  
124 ADH1A, ADH1  
125 ADH1B, ADH2, HEL-S-117  
126 ADH1C, ADH3  
1268 CNR1, CANN6, CB-R, CB1, CB1A, CB1K5, CB1R, CNR  
127281 FAM213B, C1orf93  
1286 COL4A4, CA44  
1288 COL4A6, CXDELq22.3, DELXq22.3, DFNX6  
130 ADH6, ADH-5  
130399 ACVR1C, ACVRLK7, ALK7  
131 ADH7, ADH4  
185 AGTR1, AG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, HAT1R  
186 AGTR2, AT2, ATGR2, MRX88  
1909 EDNRA, ET-A, ETA, ETA-R, ETAR, ETRA, MFDA, hET-AR  
1956 EGFR, ERBB, ERBB1, HER1, NISBD2, PIG61, mENA  
2033 EP300, KAT3B, RSTS2, p300  
2045 EPHA7, EHK-3, EHK3, EK11, HEK11  
221 ALDH3B1, ALDH4, ALDH7  
222 ALDH3B2, ALDH8  
2247 FGF2, BFGF, FGF-2, FGFB, HBGF-2  
2273 FHL1, FHL-1, FHL1A, FHL1B, FLH1A, KYOT, SLIM, SLIM-1, SLIM1, SLIMMER, XMPMA  
2277 FIGF, VEGF-D, VEGFD  
2318 FLNC, ABP-280, ABP280A, ABPA, ABPL, FLN2, MFM5, MPD4  
23411 SIRT1, SIR2, SIR2L1, hSIR2  
2353 FOS, AP-1, C-FOS, p55  
2642 GCGR, GGR, GL-R  
2735 GLI1, GLI  
2770 GNAI1, Gi  
2771 GNAI2, GIP, GNAI2B, H_LUCA15.1, H_LUCA16.1  
2773 GNAI3, 87U6, ARCND1  
2775 GNAO1, EIEE17, G-ALPHA-o, GNAO  
2782 GNB1  
2790 GNG10  
285 ANGPT2, AGPT2, ANG2  
3371 TNC, 150-225, DFNA56, GMEM, GP, HXB, JI, TN, TN-C  
3480 IGF1R, CD221, IGFIR, IGFR, JTK13  
3569 IL6, BSF2, HGF, HSF, IFNB2, IL-6  
3570 IL6R, CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80  
3589 IL11, AGIF, IL-11  
3680 ITGA9, ALPHA-RLC, ITGA4L, RLC  
3685 ITGAV, CD51, MSK8, VNRA, VTNR  
3691 ITGB4, CD104  
3694 ITGB6, AI1H  
3696 ITGB8  
3845 KRAS, C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RASK2  
3977 LIFR, CD118, LIF-R, SJS2, STWS, SWS  
4089 SMAD4, DPC4, JIP, MADH4, MYHRS  
472 ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1  
4923 NTSR1, NTR  
5241 PGR, NR3C3, PR  
5294 PIK3CG, PI3CG, PI3K, PI3Kgamma, PIK3, p110gamma, p120-PI3K  
5331 PLCB3  
54331 GNG2  
5499 PPP1CA, PP-1A, PP1A, PP1alpha, PPP1A  
5500 PPP1CB, HEL-S-80p, PP-1B, PP1B, PP1beta, PPP1CD  
5501 PPP1CC, PP-1G, PP1C, PPP1G  
5502 PPP1R1A, I1, IPP1  
5527 PPP2R5C, B56G, PR61G  
5530 PPP3CA, CALN, CALNA, CALNA1, CCN1, CNA1, PPP2B  
5592 PRKG1, AAT8, PKG, PRKG1B, PRKGR1B, cGK, cGK_1, cGK1, cGKI, cGKI-BETA, cGKI-alpha  
5593 PRKG2, PRKGR2, cGK2, cGKII  
5649 RELN, ETL7, LIS2, PRO1598, RL  
5742 PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS  
5747 PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK  
5829 PXN  
596 BCL2, Bcl-2, PPP1R50  
624 BDKRB2, B2R, BK-2, BK2, BKR2, BRB2  
6346 CCL1, I-309, P500, SCYA1, SISe, TCA3  
6367 CCL22, A-152E5.1, ABCD-1, DC/B-CK, MDC, SCYA22, STCP-1  
6387 CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B  
64321 SOX17, VUR3  
6446 SGK1, SGK  
6464 SHC1, SHC, SHCA  
650 BMP2, BDA2, BMP2A  
6714 SRC, ASV, SRC1, c-SRC, p60-Src  
6750 SST, SMST  
6752 SSTR2  
6865 TACR2, NK2R, NKNAR, SKR, TAC2R  
7048 TGFBR2, AAT3, FAA3, LDS1B, LDS2, LDS2B, MFS2, RIIC, TAAD2, TGFR-2, TGFbeta-RII  
7060 THBS4, TSP-4, TSP4  
7148 TNXB, EDS3, HXBL, TENX, TN-X, TNX, TNXB1, TNXB2, TNXBS, VUR8, XB, XBS  
7157 TP53, BCC7, LFS1, P53, TRP53  
83439 TCF7L1, TCF-3, TCF3  
8554 PIAS1, DDXBP1, GBP, GU/RH-II, ZMIZ3  
857 CAV1, BSCL3, CGL3, LCCNS, MSTP085, PPH3, VIP21, CAV  
859 CAV3, LGMD1C, LQT9, VIP-21, VIP21  
8639 AOC3, HPAO, SSAO, VAP-1, VAP1  
8835 SOCS2, CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2  
9306 SOCS6, CIS-4, CIS4, HSPC060, SOCS-4, SOCS-6, SOCS4, SSI4, STAI4, STATI4  
94274 PPP1R14A, CPI-17, CPI17, PPP1INL  
9475 ROCK2, ROCK-II  
9630 GNA14  
cpd:C00002 ATP  
cpd:C00427 Prostaglandin H2  
cpd:C00575 3',5'-Cyclic AMP  
cpd:C02135 Angiotensin II  
cpd:C16587 3-Carbamoyl-2-phenylpropionaldehyde  
hsa-miR-101-3p hsa-miR-101-3p  
hsa-miR-101-5p hsa-miR-101-5p  
hsa-miR-107 hsa-miR-107  
hsa-miR-125a-5p hsa-miR-125a-5p  
hsa-miR-125b-5p hsa-miR-125b-5p  
hsa-miR-126-5p hsa-miR-126-5p  
hsa-miR-135b-5p hsa-miR-135b-5p  
hsa-miR-145-5p hsa-miR-145-5p  
hsa-miR-149-5p hsa-miR-149-5p  
hsa-miR-15a-5p hsa-miR-15a-5p  
hsa-miR-16-5p hsa-miR-16-5p  
hsa-miR-17-5p hsa-miR-17-5p  
hsa-miR-181a-5p hsa-miR-181a-5p  
hsa-miR-185-5p hsa-miR-185-5p  
hsa-miR-186-5p hsa-miR-186-5p  
hsa-miR-192-5p hsa-miR-192-5p  
hsa-miR-193a-5p hsa-miR-193a-5p  
hsa-miR-194-5p hsa-miR-194-5p  
hsa-miR-197-3p hsa-miR-197-3p  
hsa-miR-19b-1-5p hsa-miR-19b-1-5p  
hsa-miR-20a-5p hsa-miR-20a-5p  
hsa-miR-21-5p hsa-miR-21-5p  
hsa-miR-217 hsa-miR-217  
hsa-miR-224-5p hsa-miR-224-5p  
hsa-miR-24-2-5p hsa-miR-24-2-5p  
hsa-miR-31-5p hsa-miR-31-5p  
hsa-miR-324-5p hsa-miR-324-5p  
hsa-miR-326 hsa-miR-326  
hsa-miR-335-5p hsa-miR-335-5p  
hsa-miR-340-5p hsa-miR-340-5p  
hsa-miR-34a-5p hsa-miR-34a-5p  
hsa-miR-374a-5p hsa-miR-374a-5p  
hsa-miR-376a-3p hsa-miR-376a-3p  
hsa-miR-376a-5p hsa-miR-376a-5p  
hsa-miR-376b-3p hsa-miR-376b-3p  
hsa-miR-376c-3p hsa-miR-376c-3p  
hsa-miR-379-5p hsa-miR-379-5p  
hsa-miR-380-5p hsa-miR-380-5p  
hsa-miR-421 hsa-miR-421  
hsa-miR-424-5p hsa-miR-424-5p  
hsa-miR-452-5p hsa-miR-452-5p  
hsa-miR-486-5p hsa-miR-486-5p  
hsa-miR-542-5p hsa-miR-542-5p  
hsa-miR-590-5p hsa-miR-590-5p  
hsa-miR-7-5p hsa-miR-7-5p  
hsa-miR-708-5p hsa-miR-708-5p  
hsa-miR-760 hsa-miR-760  
hsa-miR-766-3p hsa-miR-766-3p  
hsa-miR-96-5p hsa-miR-96-5p  
hsa-miR-98-5p hsa-miR-98-5p  
hsa-miR-99b-5p hsa-miR-99b-5p  

Sub-Structures

Start Node Type # Nodes Perturbation p-Value Enrichment
Start Node Type # Nodes Perturbation p-Value Enrichment

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Download Extracted Sub-structures