Pathway Substructures
Analysis Description
- Id
- e27566c7c7c7cdc1615eccccf9dad14e
- Disease
- Bladder Urothelial Carcinoma All Stages
- Extraction p-value
- 1.0E-6
- Enrichment p-value
- 0.05
- Min number of nodes
- 5
- Backward visit
Nodes of Interest
| Id | Name | Details |
|---|---|---|
| 100137049 | PLA2G4B, HsT16992, cPLA2-beta | |
| 10235 | RASGRP2, CALDAG-GEFI, CDC25L | |
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | |
| 10267 | RAMP1 | |
| 10459 | MAD2L2, MAD2B, POLZ2, REV7 | |
| 108 | ADCY2, AC2, HBAC2 | |
| 1129 | CHRM2, HM2 | |
| 124 | ADH1A, ADH1 | |
| 1288 | COL4A6, CXDELq22.3, DELXq22.3, DFNX6 | |
| 1399 | CRKL | |
| 1440 | CSF3, C17orf33, CSF3OS, GCSF, G-CSF | |
| 155 | ADRB3, BETA3AR | |
| 162417 | NAGS, AGAS, ARGA | |
| 1793 | DOCK1, DOCK180, ced5 | |
| 1843 | DUSP1, CL100, HVH1, MKP-1, MKP1, PTPN10 | |
| 1942 | EFNA1, B61, ECKLG, EFL1, EPLG1, LERK-1, LERK1, TNFAIP4 | |
| 1945 | EFNA4, EFL4, EPLG4, LERK4 | |
| 1956 | EGFR, ERBB, ERBB1, HER1, NISBD2, PIG61, mENA | |
| 2042 | EPHA3, EK4, ETK, ETK1, HEK, HEK4, TYRO4 | |
| 2206 | MS4A2, APY, ATOPY, FCER1B, FCERI, IGEL, IGER, IGHER, MS4A1 | |
| 2252 | FGF7, HBGF-7, KGF | |
| 2254 | FGF9, FGF-9, GAF, HBFG-9, HBGF-9, SYNS3 | |
| 2255 | FGF10 | |
| 2260 | FGFR1, BFGFR, CD331, CEK, FGFBR, FGFR-1, FLG, FLT-2, FLT2, HBGFR, HH2, HRTFDS, KAL2, N-SAM, OGD, bFGF-R-1 | |
| 2273 | FHL1, FHL-1, FHL1A, FHL1B, FLH1A, KYOT, SLIM, SLIM-1, SLIM1, SLIMMER, XMPMA | |
| 2277 | FIGF, VEGF-D, VEGFD | |
| 2318 | FLNC, ABP-280, ABP280A, ABPA, ABPL, FLN2, MFM5, MPD4 | |
| 23236 | PLCB1, EIEE12, PI-PLC, PLC-154, PLC-I, PLC154, PLCB1A, PLCB1B | |
| 23533 | PIK3R5, F730038I15Rik, FOAP-2, P101-PI3K, p101 | |
| 25759 | SHC2, SCK, SHCB, SLI | |
| 2769 | GNA15, GNA16 | |
| 2770 | GNAI1, Gi | |
| 2771 | GNAI2, GIP, GNAI2B, H_LUCA15.1, H_LUCA16.1 | |
| 2773 | GNAI3, 87U6, ARCND1 | |
| 2778 | GNAS, AHO, C20orf45, GNAS1, GPSA, GSA, GSP, NESP, POH, SCG6, SgVI | |
| 2781 | GNAZ | |
| 2917 | GRM7, GLUR7, GPRC1G, MGLU7, MGLUR7, PPP1R87 | |
| 3082 | HGF, DFNB39, F-TCF, HGFB, HPTA, SF | |
| 3164 | NR4A1, GFRP1, HMR, N10, NAK-1, NGFIB, NP10, NUR77, TR3 | |
| 3381 | IBSP, BNSP, BSP, BSP-II, SP-II | |
| 3479 | IGF1, IGF-I, IGF1A, IGFI | |
| 3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | |
| 3678 | ITGA5, CD49e, FNRA, VLA-5, VLA5A | |
| 3690 | ITGB3, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT | |
| 3710 | ITPR3, IP3R, IP3R3 | |
| 3718 | JAK3, JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK | |
| 3815 | KIT, C-Kit, CD117, PBT, SCFR | |
| 3972 | LHB, CGB4, HH23, LSH-B, hLHB | |
| 399694 | SHC4, RaLP, SHCD | |
| 4085 | MAD2L1, HSMAD2, MAD2 | |
| 4170 | MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT | |
| 443 | ASPA, ACY2, ASP | |
| 4804 | NGFR, CD271, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR | |
| 4830 | NME1, AWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1 | |
| 4893 | NRAS, ALPS4, CMNS, N-ras, NCMS, NRAS1, NS6 | |
| 4908 | NTF3, HDNF, NGF-2, NGF2, NT-3, NT3 | |
| 4915 | NTRK2, GP145-TrkB, TRKB, trk-B | |
| 5137 | PDE1C, Hcam3, cam-PDE_1C, hCam-3 | |
| 5138 | PDE2A, CGS-PDE, PDE2A1, PED2A4, cGSPDE | |
| 5156 | PDGFRA, CD140A, PDGFR-2, PDGFR2, RHEPDGFRA | |
| 5290 | PIK3CA, CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha | |
| 5294 | PIK3CG, PI3CG, PI3K, PI3Kgamma, PIK3, p110gamma, p120-PI3K | |
| 5295 | PIK3R1, AGM7, GRB1, IMD36, p85, p85-ALPHA | |
| 5296 | PIK3R2, MPPH, MPPH1, P85B, p85, p85-BETA | |
| 5322 | PLA2G5, FRFB, GV-PLA2, PLA2-10, hVPLA(2) | |
| 5330 | PLCB2, PLC-beta-2 | |
| 5331 | PLCB3 | |
| 5332 | PLCB4, ARCND2, PI-PLC | |
| 53358 | SHC3, N-Shc, NSHC, RAI, SHCC | |
| 5427 | POLE2, DPE2 | |
| 5499 | PPP1CA, PP-1A, PP1A, PP1alpha, PPP1A | |
| 5500 | PPP1CB, HEL-S-80p, PP-1B, PP1B, PP1beta, PPP1CD | |
| 5501 | PPP1CC, PP-1G, PP1C, PPP1G | |
| 5502 | PPP1R1A, I1, IPP1 | |
| 5579 | PRKCB, PKC-beta, PKCB, PRKCB1, PRKCB2 | |
| 5592 | PRKG1, AAT8, PKG, PRKG1B, PRKGR1B, cGK, cGK_1, cGK1, cGKI, cGKI-BETA, cGKI-alpha | |
| 5603 | MAPK13, MAPK_13, MAPK-13, PRKM13, SAPK4, p38delta | |
| 5649 | RELN, ETL7, LIS2, PRO1598, RL | |
| 5745 | PTH1R, PFE, PTHR, PTHR1 | |
| 5747 | PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK | |
| 5829 | PXN | |
| 58494 | JAM2, C21orf43, CD322, JAM-B, JAMB, PRO245, VE-JAM, VEJAM | |
| 5881 | RAC3 | |
| 596 | BCL2, Bcl-2, PPP1R50 | |
| 6241 | RRM2, R2, RR2, RR2M | |
| 6258 | RXRG, NR2B3, RXRC | |
| 6263 | RYR3, RYR-3 | |
| 627 | BDNF, ANON2, BULN2 | |
| 6363 | CCL19, CKb11, ELC, MIP-3b, MIP3B, SCYA19 | |
| 6387 | CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B | |
| 6464 | SHC1, SHC, SHCA | |
| 653689 | GSTT2B, GSTT2P | |
| 6714 | SRC, ASV, SRC1, c-SRC, p60-Src | |
| 6751 | SSTR1, SRIF-2, SS-1-R, SS1-R, SS1R | |
| 699 | BUB1, BUB1A, BUB1L, hBUB1 | |
| 7048 | TGFBR2, AAT3, FAA3, LDS1B, LDS2, LDS2B, MFS2, RIIC, TAAD2, TGFR-2, TGFbeta-RII | |
| 7083 | TK1, TK2 | |
| 7148 | TNXB, EDS3, HXBL, TENX, TN-X, TNX, TNXB1, TNXB2, TNXBS, VUR8, XB, XBS | |
| 7272 | TTK, CT96, ESK, MPH1, MPS1, MPS1L1, PYT | |
| 7371 | UCK2, TSA903, UK, UMPK | |
| 781 | CACNA2D1, CACNA2, CACNL2A, CCHL2A, LINC01112, lncRNA-N3, MHS3 | |
| 785 | CACNB4, CAB4, CACNLB4, EA5, EIG9, EJM, EJM4, EJM6 | |
| 81607 | PVRL4, EDSS1, LNIR, PRR4, nectin-4 | |
| 83700 | JAM3, JAM-2, JAM-3, JAM-C, JAMC | |
| 8503 | PIK3R3, p55, p55-GAMMA, p55PIK | |
| 8787 | RGS9, PERRS, RGS9L | |
| 890 | CCNA2, CCN1, CCNA | |
| 8912 | CACNA1H, CACNA1HB, Cav3.2, ECA6, EIG6 | |
| 9170 | LPAR2, EDG-4, EDG4, LPA-2, LPA2 | |
| 9560 | CCL4L2, AT744.2, CCL4L, SCYA4L, SCYQ4L2 | |
| 9564 | BCAR1, CAS, CAS1, CASS1, CRKAS, P130Cas | |
| 9630 | GNA14 | |
| 991 | CDC20, CDC20A, bA276H19.3, p55CDC | |
| cpd:C00020 | AMP | |
| cpd:C00076 | Calcium cation | |
| cpd:C00165 | Diacylglycerol | |
| cpd:C00214 | Thymidine | |
| cpd:C00219 | Arachidonate | |
| cpd:C00286 | dGTP | |
| cpd:C00363 | dTDP | |
| cpd:C00458 | dCTP | |
| cpd:C00459 | dTTP | |
| cpd:C00483 | Tyramine | |
| cpd:C00696 | Prostaglandin D2 | |
| cpd:C00942 | 3',5'-Cyclic GMP | |
| cpd:C01312 | Prostaglandin I2 | |
| cpd:C01346 | dUDP | |
| cpd:C02090 | Trypanothione | |
| cpd:C02135 | Angiotensin II | |
| cpd:C03170 | Trypanothione disulfide | |
| cpd:C04635 | 1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine | |
| cpd:C04637 | 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate | |
| cpd:C05634 | 5-Hydroxyindoleacetaldehyde | |
| cpd:C05744 | Acetoacetyl-[acp] | |
| cpd:C05745 | Butyryl-[acp] | |
| cpd:C05746 | 3-Oxohexanoyl-[acp] | |
| cpd:C05747 | (R)-3-Hydroxyhexanoyl-[acp] | |
| cpd:C05748 | trans-Hex-2-enoyl-[acp] | |
| cpd:C05749 | Hexanoyl-[acp] | |
| cpd:C05750 | 3-Oxooctanoyl-[acp] | |
| cpd:C07645 | Aldophosphamide | |
| cpd:C13050 | Cyclic ADP-ribose | |
| cpd:C14852 | Benzo[a]pyrene-7,8-diol | |
| hsa-miR-106a-5p | hsa-miR-106a-5p | |
| hsa-miR-106b-5p | hsa-miR-106b-5p | |
| hsa-miR-133b | hsa-miR-133b | |
| hsa-miR-142-5p | hsa-miR-142-5p | |
| hsa-miR-148b-5p | hsa-miR-148b-5p | |
| hsa-miR-15a-5p | hsa-miR-15a-5p | |
| hsa-miR-15b-5p | hsa-miR-15b-5p | |
| hsa-miR-16-5p | hsa-miR-16-5p | |
| hsa-miR-17-5p | hsa-miR-17-5p | |
| hsa-miR-181a-5p | hsa-miR-181a-5p | |
| hsa-miR-181b-5p | hsa-miR-181b-5p | |
| hsa-miR-182-5p | hsa-miR-182-5p | |
| hsa-miR-183-5p | hsa-miR-183-5p | |
| hsa-miR-18a-5p | hsa-miR-18a-5p | |
| hsa-miR-192-5p | hsa-miR-192-5p | |
| hsa-miR-194-5p | hsa-miR-194-5p | |
| hsa-miR-196b-5p | hsa-miR-196b-5p | |
| hsa-miR-205-5p | hsa-miR-205-5p | |
| hsa-miR-20a-5p | hsa-miR-20a-5p | |
| hsa-miR-21-5p | hsa-miR-21-5p | |
| hsa-miR-301a-3p | hsa-miR-301a-3p | |
| hsa-miR-32-5p | hsa-miR-32-5p | |
| hsa-miR-335-5p | hsa-miR-335-5p | |
| hsa-miR-33a-5p | hsa-miR-33a-5p | |
| hsa-miR-34a-5p | hsa-miR-34a-5p | |
| hsa-miR-3934-5p | hsa-miR-3934-5p | |
| hsa-miR-423-5p | hsa-miR-423-5p | |
| hsa-miR-425-5p | hsa-miR-425-5p | |
| hsa-miR-429 | hsa-miR-429 | |
| hsa-miR-484 | hsa-miR-484 | |
| hsa-miR-512-5p | hsa-miR-512-5p | |
| hsa-miR-519a-3p | hsa-miR-519a-3p | |
| hsa-miR-520b | hsa-miR-520b | |
| hsa-miR-584-5p | hsa-miR-584-5p | |
| hsa-miR-589-5p | hsa-miR-589-5p | |
| hsa-miR-590-5p | hsa-miR-590-5p | |
| hsa-miR-652-3p | hsa-miR-652-3p | |
| hsa-miR-7-5p | hsa-miR-7-5p | |
| hsa-miR-708-5p | hsa-miR-708-5p | |
| hsa-miR-744-5p | hsa-miR-744-5p | |
| hsa-miR-92a-3p | hsa-miR-92a-3p | |
| hsa-miR-93-5p | hsa-miR-93-5p | |
| hsa-miR-940 | hsa-miR-940 |
Sub-Structures
| Start Node | Type | # Nodes | Perturbation | p-Value | Enrichment |
|---|---|---|---|---|---|
| Start Node | Type | # Nodes | Perturbation | p-Value | Enrichment |