Pathway Substructures

271 Nodes of Interest
20,863 Sub-Structures

Analysis Description

Id
14398fbb9b9fe0dd97dced9bca4aa164
Disease
Bladder Urothelial Carcinoma All Stages
Extraction p-value
0.1
Enrichment p-value
0.05
Min number of nodes
5
Backward visit

Nodes of Interest

Id Details
100137049 PLA2G4B, HsT16992, cPLA2-beta  
10235 RASGRP2, CALDAG-GEFI, CDC25L  
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1  
10267 RAMP1  
10335 MRVI1, IRAG, JAW1L  
10398 MYL9, LC20, MLC-2C, MLC2, MRLC1, MYRL2  
10459 MAD2L2, MAD2B, POLZ2, REV7  
108 ADCY2, AC2, HBAC2  
1129 CHRM2, HM2  
124 ADH1A, ADH1  
125 ADH1B, ADH2, HEL-S-117  
1288 COL4A6, CXDELq22.3, DELXq22.3, DFNX6  
1398 CRK, CRKII, p38  
1399 CRKL  
1440 CSF3, C17orf33, CSF3OS, GCSF, G-CSF  
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1  
155 ADRB3, BETA3AR  
162417 NAGS, AGAS, ARGA  
1793 DOCK1, DOCK180, ced5  
1841 DTYMK, CDC8, PP3731, TMPK, TYMK  
1843 DUSP1, CL100, HVH1, MKP-1, MKP1, PTPN10  
185 AGTR1, AG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, HAT1R  
1942 EFNA1, B61, ECKLG, EFL1, EPLG1, LERK-1, LERK1, TNFAIP4  
1945 EFNA4, EFL4, EPLG4, LERK4  
1956 EGFR, ERBB, ERBB1, HER1, NISBD2, PIG61, mENA  
2042 EPHA3, EK4, ETK, ETK1, HEK, HEK4, TYRO4  
2045 EPHA7, EHK-3, EHK3, EK11, HEK11  
2099 ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1  
2175 FANCA, FA, FA-H, FA1, FAA, FACA, FAH, FANCH  
2177 FANCD2, FA-D2, FA4, FACD, FAD, FAD2, FANCD  
2187 FANCB, FA2, FAAP90, FAAP95, FAB, FACB  
2205 FCER1A, FCE1A, FcERI  
2206 MS4A2, APY, ATOPY, FCER1B, FCERI, IGEL, IGER, IGHER, MS4A1  
2247 FGF2, BFGF, FGF-2, FGFB, HBGF-2  
2252 FGF7, HBGF-7, KGF  
2254 FGF9, FGF-9, GAF, HBFG-9, HBGF-9, SYNS3  
2255 FGF10  
2260 FGFR1, BFGFR, CD331, CEK, FGFBR, FGFR-1, FLG, FLT-2, FLT2, HBGFR, HH2, HRTFDS, KAL2, N-SAM, OGD, bFGF-R-1  
2273 FHL1, FHL-1, FHL1A, FHL1B, FLH1A, KYOT, SLIM, SLIM-1, SLIM1, SLIMMER, XMPMA  
2277 FIGF, VEGF-D, VEGFD  
2318 FLNC, ABP-280, ABP280A, ABPA, ABPL, FLN2, MFM5, MPD4  
23236 PLCB1, EIEE12, PI-PLC, PLC-154, PLC-I, PLC154, PLCB1A, PLCB1B  
23533 PIK3R5, F730038I15Rik, FOAP-2, P101-PI3K, p101  
23594 ORC6, ORC6L  
245972 ATP6V0D2, ATP6D2, VMA6  
2534 FYN, SLK, SYN, p59-FYN  
25759 SHC2, SCK, SHCB, SLI  
27306 HPGDS, GSTS, GSTS1, GSTS1-1, PGD2, PGDS  
2767 GNA11, FBH, FBH2, FHH2, GNA-11, HHC2, HYPOC2  
2769 GNA15, GNA16  
2770 GNAI1, Gi  
2771 GNAI2, GIP, GNAI2B, H_LUCA15.1, H_LUCA16.1  
2773 GNAI3, 87U6, ARCND1  
2778 GNAS, AHO, C20orf45, GNAS1, GPSA, GSA, GSP, NESP, POH, SCG6, SgVI  
2781 GNAZ  
2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2  
29089 UBE2T, FANCT, HSPC150, PIG50  
2917 GRM7, GLUR7, GPRC1G, MGLU7, MGLUR7, PPP1R87  
2920 CXCL2, CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2  
2949 GSTM5, GSTM5-5, GTM5  
3082 HGF, DFNB39, F-TCF, HGFB, HPTA, SF  
316 AOX1, AO, AOH1  
3164 NR4A1, GFRP1, HMR, N10, NAK-1, NGFIB, NP10, NUR77, TR3  
3381 IBSP, BNSP, BSP, BSP-II, SP-II  
3479 IGF1, IGF-I, IGF1A, IGFI  
3569 IL6, BSF2, HGF, HSF, IFNB2, IL-6  
3678 ITGA5, CD49e, FNRA, VLA-5, VLA5A  
3679 ITGA7  
3680 ITGA9, ALPHA-RLC, ITGA4L, RLC  
3690 ITGB3, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT  
3710 ITPR3, IP3R, IP3R3  
3718 JAK3, JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK  
3760 KCNJ3, GIRK1, KGA, KIR3.1  
3779 KCNMB1, BKbeta1, K(VCA)beta, SLO-BETA, hbeta1, hslo-beta, k(VCA)beta-1, slo-beta-1  
3815 KIT, C-Kit, CD117, PBT, SCFR  
3972 LHB, CGB4, HH23, LSH-B, hLHB  
399694 SHC4, RaLP, SHCD  
4085 MAD2L1, HSMAD2, MAD2  
4129 MAOB  
4170 MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT  
4306 NR3C2, MCR, MLR, MR, NR3C2VIT  
443 ASPA, ACY2, ASP  
4629 MYH11, AAT4, FAA4, SMHC, SMMHC  
4638 MYLK, AAT7, KRP, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, MYLK1, smMLCK  
4660 PPP1R12B, MYPT2, PP1bp55  
4804 NGFR, CD271, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR  
4893 NRAS, ALPS4, CMNS, N-ras, NCMS, NRAS1, NS6  
4908 NTF3, HDNF, NGF-2, NGF2, NT-3, NT3  
4915 NTRK2, GP145-TrkB, TRKB, trk-B  
4916 NTRK3, GP145-TrkC, TRKC, gp145(trkC)  
4998 ORC1, HSORC1, ORC1L, PARC1  
51343 FZR1, CDC20C, CDH1, FZR, FZR2, HCDH, HCDH1  
5136 PDE1A, CAM-PDE-1A, HCAM-1, HCAM1, HSPDE1A  
5137 PDE1C, Hcam3, cam-PDE_1C, hCam-3  
5138 PDE2A, CGS-PDE, PDE2A1, PED2A4, cGSPDE  
5156 PDGFRA, CD140A, PDGFR-2, PDGFR2, RHEPDGFRA  
5241 PGR, NR3C3, PR  
5290 PIK3CA, CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha  
5294 PIK3CG, PI3CG, PI3K, PI3Kgamma, PIK3, p110gamma, p120-PI3K  
5295 PIK3R1, AGM7, GRB1, IMD36, p85, p85-ALPHA  
5296 PIK3R2, MPPH, MPPH1, P85B, p85, p85-BETA  
5322 PLA2G5, FRFB, GV-PLA2, PLA2-10, hVPLA(2)  
5330 PLCB2, PLC-beta-2  
5331 PLCB3  
5332 PLCB4, ARCND2, PI-PLC  
53358 SHC3, N-Shc, NSHC, RAI, SHCC  
5427 POLE2, DPE2  
5499 PPP1CA, PP-1A, PP1A, PP1alpha, PPP1A  
5500 PPP1CB, HEL-S-80p, PP-1B, PP1B, PP1beta, PPP1CD  
5501 PPP1CC, PP-1G, PP1C, PPP1G  
5502 PPP1R1A, I1, IPP1  
5579 PRKCB, PKC-beta, PKCB, PRKCB1, PRKCB2  
5590 PRKCZ, PKC-ZETA, PKC2  
5592 PRKG1, AAT8, PKG, PRKG1B, PRKGR1B, cGK, cGK_1, cGK1, cGKI, cGKI-BETA, cGKI-alpha  
5603 MAPK13, MAPK_13, MAPK-13, PRKM13, SAPK4, p38delta  
5649 RELN, ETL7, LIS2, PRO1598, RL  
5728 PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1  
5733 PTGER3, EP3, EP3-I, EP3-II, EP3-III, EP3-IV, EP3e, PGE2-R  
5737 PTGFR, FP  
5745 PTH1R, PFE, PTHR, PTHR1  
5747 PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK  
581 BAX, BCL2L4  
5829 PXN  
58494 JAM2, C21orf43, CD322, JAM-B, JAMB, PRO245, VE-JAM, VEJAM  
5881 RAC3  
596 BCL2, Bcl-2, PPP1R50  
5997 RGS2, G0S8  
6241 RRM2, R2, RR2, RR2M  
6258 RXRG, NR2B3, RXRC  
6263 RYR3, RYR-3  
627 BDNF, ANON2, BULN2  
6347 CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF  
6358 CCL14, CC-1, CC-3, CKB1, HCC-1, HCC-1(1-74), HCC-1/HCC-3, HCC-3, MCIF, NCC-2, NCC2, SCYA14, SCYL2, SY14  
6363 CCL19, CKb11, ELC, MIP-3b, MIP3B, SCYA19  
6387 CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B  
6464 SHC1, SHC, SHCA  
653689 GSTT2B, GSTT2P  
6654 SOS1, GF1, GGF1, GINGF, HGF, NS4  
6655 SOS2  
6714 SRC, ASV, SRC1, c-SRC, p60-Src  
6751 SSTR1, SRIF-2, SS-1-R, SS1-R, SS1R  
699 BUB1, BUB1A, BUB1L, hBUB1  
7048 TGFBR2, AAT3, FAA3, LDS1B, LDS2, LDS2B, MFS2, RIIC, TAAD2, TGFR-2, TGFbeta-RII  
7083 TK1, TK2  
7148 TNXB, EDS3, HXBL, TENX, TN-X, TNX, TNXB1, TNXB2, TNXBS, VUR8, XB, XBS  
7272 TTK, CT96, ESK, MPH1, MPS1, MPS1L1, PYT  
7371 UCK2, TSA903, UK, UMPK  
7434 VIPR2, C16DUPq36.3, DUP7q36.3, PACAP-R-3, PACAP-R3, VIP-R-2, VPAC2, VPAC2R, VPCAP2R  
781 CACNA2D1, CACNA2, CACNL2A, CCHL2A, LINC01112, lncRNA-N3, MHS3  
783 CACNB2, CACNLB2, CAVB2, MYSB  
785 CACNB4, CAB4, CACNLB4, EA5, EIG9, EJM, EJM4, EJM6  
815 CAMK2A, CAMKA  
81607 PVRL4, EDSS1, LNIR, PRR4, nectin-4  
8318 CDC45, CDC45L, CDC45L2, PORC-PI-1  
83700 JAM3, JAM-2, JAM-3, JAM-C, JAMC  
8379 MAD1L1, MAD1, PIG9, TP53I9, TXBP181  
8503 PIK3R3, p55, p55-GAMMA, p55PIK  
8516 ITGA8  
8787 RGS9, PERRS, RGS9L  
890 CCNA2, CCN1, CCNA  
891 CCNB1, CCNB  
8912 CACNA1H, CACNA1HB, Cav3.2, ECA6, EIG6  
9088 PKMYT1, MYT1, PPP1R126  
9133 CCNB2, HsT17299  
9170 LPAR2, EDG-4, EDG4, LPA-2, LPA2  
9560 CCL4L2, AT744.2, CCL4L, SCYA4L, SCYQ4L2  
9564 BCAR1, CAS, CAS1, CASS1, CRKAS, P130Cas  
9630 GNA14  
983 CDK1, CDC2, CDC28A, P34CDC2  
990 CDC6, CDC18L, HsCDC18, HsCDC6  
991 CDC20, CDC20A, bA276H19.3, p55CDC  
993 CDC25A, CDC25A2  
cpd:C00020 AMP  
cpd:C00076 Calcium cation  
cpd:C00165 Diacylglycerol  
cpd:C00214 Thymidine  
cpd:C00219 Arachidonate  
cpd:C00286 dGTP  
cpd:C00363 dTDP  
cpd:C00364 dTMP  
cpd:C00458 dCTP  
cpd:C00459 dTTP  
cpd:C00483 Tyramine  
cpd:C00575 3',5'-Cyclic AMP  
cpd:C00641 1,2-Diacyl-sn-glycerol  
cpd:C00696 Prostaglandin D2  
cpd:C00942 3',5'-Cyclic GMP  
cpd:C01312 Prostaglandin I2  
cpd:C01346 dUDP  
cpd:C02090 Trypanothione  
cpd:C02135 Angiotensin II  
cpd:C03170 Trypanothione disulfide  
cpd:C03939 Acetyl-[acyl-carrier protein]  
cpd:C04635 1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine  
cpd:C04637 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate  
cpd:C05634 5-Hydroxyindoleacetaldehyde  
cpd:C05744 Acetoacetyl-[acp]  
cpd:C05745 Butyryl-[acp]  
cpd:C05746 3-Oxohexanoyl-[acp]  
cpd:C05747 (R)-3-Hydroxyhexanoyl-[acp]  
cpd:C05748 trans-Hex-2-enoyl-[acp]  
cpd:C05749 Hexanoyl-[acp]  
cpd:C05750 3-Oxooctanoyl-[acp]  
cpd:C05751 trans-Oct-2-enoyl-[acp]  
cpd:C05753 3-Oxodecanoyl-[acp]  
cpd:C05754 trans-Dec-2-enoyl-[acp]  
cpd:C05756 3-Oxododecanoyl-[acp]  
cpd:C05757 (R)-3-Hydroxydodecanoyl-[acp]  
cpd:C05758 trans-Dodec-2-enoyl-[acp]  
cpd:C05759 3-Oxotetradecanoyl-[acp]  
cpd:C05760 trans-Tetradec-2-enoyl-[acp]  
cpd:C05761 Tetradecanoyl-[acp]  
cpd:C05762 3-Oxohexadecanoyl-[acp]  
cpd:C05763 trans-Hexadec-2-enoyl-[acp]  
cpd:C05764 Hexadecanoyl-[acp]  
cpd:C07645 Aldophosphamide  
cpd:C13050 Cyclic ADP-ribose  
cpd:C14852 Benzo[a]pyrene-7,8-diol  
gl:G00008 (Glc)3 (GlcNAc)2 (Man)9 (PP-Dol)1  
hsa-miR-106a-5p hsa-miR-106a-5p  
hsa-miR-106b-5p hsa-miR-106b-5p  
hsa-miR-133b hsa-miR-133b  
hsa-miR-142-5p hsa-miR-142-5p  
hsa-miR-148b-5p hsa-miR-148b-5p  
hsa-miR-149-5p hsa-miR-149-5p  
hsa-miR-15a-5p hsa-miR-15a-5p  
hsa-miR-15b-5p hsa-miR-15b-5p  
hsa-miR-16-5p hsa-miR-16-5p  
hsa-miR-17-5p hsa-miR-17-5p  
hsa-miR-181a-5p hsa-miR-181a-5p  
hsa-miR-181b-5p hsa-miR-181b-5p  
hsa-miR-182-5p hsa-miR-182-5p  
hsa-miR-183-5p hsa-miR-183-5p  
hsa-miR-185-5p hsa-miR-185-5p  
hsa-miR-18a-5p hsa-miR-18a-5p  
hsa-miR-192-5p hsa-miR-192-5p  
hsa-miR-194-5p hsa-miR-194-5p  
hsa-miR-196b-5p hsa-miR-196b-5p  
hsa-miR-19b-1-5p hsa-miR-19b-1-5p  
hsa-miR-205-5p hsa-miR-205-5p  
hsa-miR-20a-5p hsa-miR-20a-5p  
hsa-miR-21-5p hsa-miR-21-5p  
hsa-miR-301a-3p hsa-miR-301a-3p  
hsa-miR-31-5p hsa-miR-31-5p  
hsa-miR-32-5p hsa-miR-32-5p  
hsa-miR-335-5p hsa-miR-335-5p  
hsa-miR-33a-5p hsa-miR-33a-5p  
hsa-miR-33b-5p hsa-miR-33b-5p  
hsa-miR-345-5p hsa-miR-345-5p  
hsa-miR-34a-5p hsa-miR-34a-5p  
hsa-miR-34c-5p hsa-miR-34c-5p  
hsa-miR-3934-5p hsa-miR-3934-5p  
hsa-miR-423-5p hsa-miR-423-5p  
hsa-miR-425-5p hsa-miR-425-5p  
hsa-miR-429 hsa-miR-429  
hsa-miR-484 hsa-miR-484  
hsa-miR-503-5p hsa-miR-503-5p  
hsa-miR-512-5p hsa-miR-512-5p  
hsa-miR-519a-3p hsa-miR-519a-3p  
hsa-miR-520b hsa-miR-520b  
hsa-miR-584-5p hsa-miR-584-5p  
hsa-miR-589-5p hsa-miR-589-5p  
hsa-miR-590-5p hsa-miR-590-5p  
hsa-miR-652-3p hsa-miR-652-3p  
hsa-miR-7-5p hsa-miR-7-5p  
hsa-miR-708-5p hsa-miR-708-5p  
hsa-miR-744-5p hsa-miR-744-5p  
hsa-miR-92a-3p hsa-miR-92a-3p  
hsa-miR-93-5p hsa-miR-93-5p  
hsa-miR-940 hsa-miR-940  
hsa-miR-96-5p hsa-miR-96-5p  

Sub-Structures

Start Node Type # Nodes Perturbation p-Value Enrichment
Start Node Type # Nodes Perturbation p-Value Enrichment

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Download Extracted Sub-structures