Pathway Substructures
Analysis Description
- Id
- 110c76d993fc6253393a92b0af8ebfe5
- Disease
- Bladder Urothelial Carcinoma Stage 1
- Extraction p-value
- 1.0E-6
- Enrichment p-value
- 0.05
- Min number of nodes
- 5
- Backward visit
Nodes of Interest
| Id | Name | Details |
|---|---|---|
| 10000 | AKT3, MPPH, MPPH2, PKB-GAMMA, PKBG, PRKBG, RAC-PK-gamma, RAC-gamma, STK-2 | |
| 100137049 | PLA2G4B, HsT16992, cPLA2-beta | |
| 10018 | BCL2L11, BAM, BIM, BOD | |
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | |
| 10267 | RAMP1 | |
| 11211 | FZD10, CD350, FZ-10, Fz10, FzE7, hFz10 | |
| 1129 | CHRM2, HM2 | |
| 117 | ADCYAP1R1, PAC1, PAC1R, PACAPR, PACAPRI | |
| 1398 | CRK, CRKII, p38 | |
| 1399 | CRKL | |
| 1440 | CSF3, C17orf33, CSF3OS, GCSF, G-CSF | |
| 151648 | SGOL1, CAID, NY-BR-85, SGO, Sgo1 | |
| 155 | ADRB3, BETA3AR | |
| 1843 | DUSP1, CL100, HVH1, MKP-1, MKP1, PTPN10 | |
| 1956 | EGFR, ERBB, ERBB1, HER1, NISBD2, PIG61, mENA | |
| 2205 | FCER1A, FCE1A, FcERI | |
| 2247 | FGF2, BFGF, FGF-2, FGFB, HBGF-2 | |
| 2252 | FGF7, HBGF-7, KGF | |
| 2254 | FGF9, FGF-9, GAF, HBFG-9, HBGF-9, SYNS3 | |
| 2255 | FGF10 | |
| 2260 | FGFR1, BFGFR, CD331, CEK, FGFBR, FGFR-1, FLG, FLT-2, FLT2, HBGFR, HH2, HRTFDS, KAL2, N-SAM, OGD, bFGF-R-1 | |
| 2273 | FHL1, FHL-1, FHL1A, FHL1B, FLH1A, KYOT, SLIM, SLIM-1, SLIM1, SLIMMER, XMPMA | |
| 2318 | FLNC, ABP-280, ABP280A, ABPA, ABPL, FLN2, MFM5, MPD4 | |
| 23236 | PLCB1, EIEE12, PI-PLC, PLC-154, PLC-I, PLC154, PLCB1A, PLCB1B | |
| 23533 | PIK3R5, F730038I15Rik, FOAP-2, P101-PI3K, p101 | |
| 2492 | FSHR, FSHRO, LGR1, ODG1 | |
| 2534 | FYN, SLK, SYN, p59-FYN | |
| 2769 | GNA15, GNA16 | |
| 2770 | GNAI1, Gi | |
| 2771 | GNAI2, GIP, GNAI2B, H_LUCA15.1, H_LUCA16.1 | |
| 2773 | GNAI3, 87U6, ARCND1 | |
| 2778 | GNAS, AHO, C20orf45, GNAS1, GPSA, GSA, GSP, NESP, POH, SCG6, SgVI | |
| 2781 | GNAZ | |
| 2885 | GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2 | |
| 2917 | GRM7, GLUR7, GPRC1G, MGLU7, MGLUR7, PPP1R87 | |
| 2920 | CXCL2, CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2 | |
| 3082 | HGF, DFNB39, F-TCF, HGFB, HPTA, SF | |
| 3164 | NR4A1, GFRP1, HMR, N10, NAK-1, NGFIB, NP10, NUR77, TR3 | |
| 3283 | HSD3B1, 3BETAHSD, HSD3B, HSDB3, HSDB3A, I, SDR11E1 | |
| 3381 | IBSP, BNSP, BSP, BSP-II, SP-II | |
| 3479 | IGF1, IGF-I, IGF1A, IGFI | |
| 3678 | ITGA5, CD49e, FNRA, VLA-5, VLA5A | |
| 3679 | ITGA7 | |
| 3680 | ITGA9, ALPHA-RLC, ITGA4L, RLC | |
| 3690 | ITGB3, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT | |
| 3704 | ITPA, C20orf37, HLC14-06-P, My049, dJ794I6.3 | |
| 3718 | JAK3, JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK | |
| 3815 | KIT, C-Kit, CD117, PBT, SCFR | |
| 3908 | LAMA2, LAMM | |
| 3972 | LHB, CGB4, HH23, LSH-B, hLHB | |
| 3973 | LHCGR, HHG, LCGR, LGR2, LH/CG-R, LH/CGR, LHR, LHRHR, LSH-R, ULG5 | |
| 3977 | LIFR, CD118, LIF-R, SJS2, STWS, SWS | |
| 399694 | SHC4, RaLP, SHCD | |
| 4085 | MAD2L1, HSMAD2, MAD2 | |
| 4129 | MAOB | |
| 4170 | MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT | |
| 4306 | NR3C2, MCR, MLR, MR, NR3C2VIT | |
| 4616 | GADD45B, GADD45BETA, MYD118 | |
| 4804 | NGFR, CD271, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR | |
| 4830 | NME1, AWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1 | |
| 4915 | NTRK2, GP145-TrkB, TRKB, trk-B | |
| 4916 | NTRK3, GP145-TrkC, TRKC, gp145(trkC) | |
| 4929 | NR4A2, HZF-3, NOT, NURR1, RNR1, TINUR | |
| 5050 | PAFAH1B3, PAFAHG | |
| 51343 | FZR1, CDC20C, CDH1, FZR, FZR2, HCDH, HCDH1 | |
| 5156 | PDGFRA, CD140A, PDGFR-2, PDGFR2, RHEPDGFRA | |
| 5241 | PGR, NR3C3, PR | |
| 5290 | PIK3CA, CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha | |
| 5294 | PIK3CG, PI3CG, PI3K, PI3Kgamma, PIK3, p110gamma, p120-PI3K | |
| 5295 | PIK3R1, AGM7, GRB1, IMD36, p85, p85-ALPHA | |
| 5296 | PIK3R2, MPPH, MPPH1, P85B, p85, p85-BETA | |
| 5330 | PLCB2, PLC-beta-2 | |
| 5331 | PLCB3 | |
| 5332 | PLCB4, ARCND2, PI-PLC | |
| 53358 | SHC3, N-Shc, NSHC, RAI, SHCC | |
| 5427 | POLE2, DPE2 | |
| 5499 | PPP1CA, PP-1A, PP1A, PP1alpha, PPP1A | |
| 5500 | PPP1CB, HEL-S-80p, PP-1B, PP1B, PP1beta, PPP1CD | |
| 5502 | PPP1R1A, I1, IPP1 | |
| 5579 | PRKCB, PKC-beta, PKCB, PRKCB1, PRKCB2 | |
| 5590 | PRKCZ, PKC-ZETA, PKC2 | |
| 5592 | PRKG1, AAT8, PKG, PRKG1B, PRKGR1B, cGK, cGK_1, cGK1, cGKI, cGKI-BETA, cGKI-alpha | |
| 5603 | MAPK13, MAPK_13, MAPK-13, PRKM13, SAPK4, p38delta | |
| 5649 | RELN, ETL7, LIS2, PRO1598, RL | |
| 5728 | PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1 | |
| 5733 | PTGER3, EP3, EP3-I, EP3-II, EP3-III, EP3-IV, EP3e, PGE2-R | |
| 5737 | PTGFR, FP | |
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | |
| 5745 | PTH1R, PFE, PTHR, PTHR1 | |
| 5747 | PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK | |
| 596 | BCL2, Bcl-2, PPP1R50 | |
| 6241 | RRM2, R2, RR2, RR2M | |
| 627 | BDNF, ANON2, BULN2 | |
| 6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | |
| 6358 | CCL14, CC-1, CC-3, CKB1, HCC-1, HCC-1(1-74), HCC-1/HCC-3, HCC-3, MCIF, NCC-2, NCC2, SCYA14, SCYL2, SY14 | |
| 6363 | CCL19, CKb11, ELC, MIP-3b, MIP3B, SCYA19 | |
| 6376 | CX3CL1, ABCD-3, C3Xkine, CXC3, CXC3C, NTN, NTT, SCYD1, fractalkine, neurotactin | |
| 6387 | CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B | |
| 6422 | SFRP1, FRP, FRP-1, FRP1, FrzA, SARP2 | |
| 6423 | SFRP2, FRP-2, SARP1, SDF-5 | |
| 6424 | SFRP4, FRP-4, FRPHE, sFRP-4 | |
| 6425 | SFRP5, SARP3 | |
| 6654 | SOS1, GF1, GGF1, GINGF, HGF, NS4 | |
| 6655 | SOS2 | |
| 6714 | SRC, ASV, SRC1, c-SRC, p60-Src | |
| 6751 | SSTR1, SRIF-2, SS-1-R, SS1-R, SS1R | |
| 7083 | TK1, TK2 | |
| 7473 | WNT3, INT4, TETAMS | |
| 7941 | PLA2G7, LDL-PLA2, LP-PLA2, PAFAD, PAFAH | |
| 81029 | WNT5B | |
| 81607 | PVRL4, EDSS1, LNIR, PRR4, nectin-4 | |
| 8325 | FZD8, FZ-8, hFZ8 | |
| 8379 | MAD1L1, MAD1, PIG9, TP53I9, TXBP181 | |
| 8503 | PIK3R3, p55, p55-GAMMA, p55PIK | |
| 8516 | ITGA8 | |
| 8605 | PLA2G4C, CPLA2-gamma | |
| 8787 | RGS9, PERRS, RGS9L | |
| 891 | CCNB1, CCNB | |
| 9021 | SOCS3, ATOD4, CIS3, Cish3, SOCS-3, SSI-3, SSI3 | |
| 9133 | CCNB2, HsT17299 | |
| 9170 | LPAR2, EDG-4, EDG4, LPA-2, LPA2 | |
| 9560 | CCL4L2, AT744.2, CCL4L, SCYA4L, SCYQ4L2 | |
| 9564 | BCAR1, CAS, CAS1, CASS1, CRKAS, P130Cas | |
| 9630 | GNA14 | |
| cpd:C00214 | Thymidine | |
| cpd:C00286 | dGTP | |
| cpd:C00363 | dTDP | |
| cpd:C00364 | dTMP | |
| cpd:C00427 | Prostaglandin H2 | |
| cpd:C00575 | 3',5'-Cyclic AMP | |
| cpd:C00696 | Prostaglandin D2 | |
| cpd:C01176 | 17alpha-Hydroxyprogesterone | |
| cpd:C01312 | Prostaglandin I2 | |
| cpd:C01346 | dUDP | |
| cpd:C03170 | Trypanothione disulfide | |
| cpd:C04598 | 2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine | |
| cpd:C04635 | 1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine | |
| cpd:C05138 | 17alpha-Hydroxypregnenolone | |
| cpd:C05488 | 11-Deoxycortisol | |
| cpd:C05634 | 5-Hydroxyindoleacetaldehyde | |
| cpd:C05744 | Acetoacetyl-[acp] | |
| cpd:C05745 | Butyryl-[acp] | |
| cpd:C05746 | 3-Oxohexanoyl-[acp] | |
| cpd:C05747 | (R)-3-Hydroxyhexanoyl-[acp] | |
| cpd:C05748 | trans-Hex-2-enoyl-[acp] | |
| cpd:C05749 | Hexanoyl-[acp] | |
| cpd:C05750 | 3-Oxooctanoyl-[acp] | |
| cpd:C05751 | trans-Oct-2-enoyl-[acp] | |
| cpd:C05753 | 3-Oxodecanoyl-[acp] | |
| cpd:C05756 | 3-Oxododecanoyl-[acp] | |
| hsa-miR-106a-5p | hsa-miR-106a-5p | |
| hsa-miR-106b-5p | hsa-miR-106b-5p | |
| hsa-miR-107 | hsa-miR-107 | |
| hsa-miR-126-5p | hsa-miR-126-5p | |
| hsa-miR-142-5p | hsa-miR-142-5p | |
| hsa-miR-148b-5p | hsa-miR-148b-5p | |
| hsa-miR-149-5p | hsa-miR-149-5p | |
| hsa-miR-15a-5p | hsa-miR-15a-5p | |
| hsa-miR-15b-5p | hsa-miR-15b-5p | |
| hsa-miR-16-5p | hsa-miR-16-5p | |
| hsa-miR-17-5p | hsa-miR-17-5p | |
| hsa-miR-181a-5p | hsa-miR-181a-5p | |
| hsa-miR-181b-5p | hsa-miR-181b-5p | |
| hsa-miR-182-5p | hsa-miR-182-5p | |
| hsa-miR-186-5p | hsa-miR-186-5p | |
| hsa-miR-18a-5p | hsa-miR-18a-5p | |
| hsa-miR-192-5p | hsa-miR-192-5p | |
| hsa-miR-196b-5p | hsa-miR-196b-5p | |
| hsa-miR-19b-1-5p | hsa-miR-19b-1-5p | |
| hsa-miR-20a-5p | hsa-miR-20a-5p | |
| hsa-miR-301a-3p | hsa-miR-301a-3p | |
| hsa-miR-323b-5p | hsa-miR-323b-5p | |
| hsa-miR-324-5p | hsa-miR-324-5p | |
| hsa-miR-335-5p | hsa-miR-335-5p | |
| hsa-miR-33a-5p | hsa-miR-33a-5p | |
| hsa-miR-33b-5p | hsa-miR-33b-5p | |
| hsa-miR-345-5p | hsa-miR-345-5p | |
| hsa-miR-34a-5p | hsa-miR-34a-5p | |
| hsa-miR-3934-5p | hsa-miR-3934-5p | |
| hsa-miR-423-5p | hsa-miR-423-5p | |
| hsa-miR-424-5p | hsa-miR-424-5p | |
| hsa-miR-425-5p | hsa-miR-425-5p | |
| hsa-miR-429 | hsa-miR-429 | |
| hsa-miR-484 | hsa-miR-484 | |
| hsa-miR-512-5p | hsa-miR-512-5p | |
| hsa-miR-518a-5p | hsa-miR-518a-5p | |
| hsa-miR-520b | hsa-miR-520b | |
| hsa-miR-584-5p | hsa-miR-584-5p | |
| hsa-miR-652-3p | hsa-miR-652-3p | |
| hsa-miR-7-5p | hsa-miR-7-5p | |
| hsa-miR-708-5p | hsa-miR-708-5p | |
| hsa-miR-744-5p | hsa-miR-744-5p | |
| hsa-miR-92a-3p | hsa-miR-92a-3p | |
| hsa-miR-940 | hsa-miR-940 |
Sub-Structures
| Start Node | Type | # Nodes | Perturbation | p-Value | Enrichment |
|---|---|---|---|---|---|
| Start Node | Type | # Nodes | Perturbation | p-Value | Enrichment |