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DB08602 - 3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one


Identification
Name 3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one
Accession Number DB08602
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 304.315
Groups experimental
Monoisotopic Weight 304.048190052
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
Name High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
Gene Name PDE7A
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available

Predictions


Id Partner name Gene Name Score
6216 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A PDE8A 0.0868
691 cAMP-specific 3',5'-cyclic phosphodiesterase 7B PDE7B 0.0855
2358 cAMP-specific 3',5'-cyclic phosphodiesterase 4D PDE4D 0.0841
4109 cAMP-specific 3',5'-cyclic phosphodiesterase 4C PDE4C 0.0644
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0553
5360 High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A PDE9A 0.0512
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0499
3806 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A 0.0472
2256 cGMP-inhibited 3',5'-cyclic phosphodiesterase B PDE3B 0.0429
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0405
6217 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B PDE8B 0.0402
1178 Adenosine A2a receptor ADORA2A 0.0333
16 Adenosine A1 receptor ADORA1 0.033
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0317
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0245
492 Histamine H1 receptor HRH1 0.0158
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