DT-Web

DB08137 - (4E)-N-(4-fluorophenyl)-4-[(phenylcarbonyl)imino]-4H-pyrazole-3-carboxamide


Identification
Name (4E)-N-(4-fluorophenyl)-4-[(phenylcarbonyl)imino]-4H-pyrazole-3-carboxamide
Accession Number DB08137
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 324.3091
Groups experimental
Monoisotopic Weight 324.102253885
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Cell division protein kinase 2
Name Cell division protein kinase 2
Gene Name CDK2
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.6166

Predictions


Id Partner name Gene Name Score
6235 Cyclin-A2 CCNA2 0.2743
1742 D-HSCDK2 CDK2deltaT 0.025
1771 Cell division control protein 2 homolog CDK1 0.023
3321 Cell division control protein 2 homolog CRK2 0.023
1058 Cell division protein kinase 5 CDK5 0.022
2511 MAP kinase-activated protein kinase 2 MAPKAPK2 0.0127
1422 Serine/threonine-protein kinase 6 AURKA 0.0104
3959 Cell division protein kinase 4 CDK4 0.0073
1176 Mitogen-activated protein kinase 1 MAPK1 0.0069
6321 Cyclin-dependent kinase 5 activator 1 CDK5R1 0.0049
1721 Glycogen synthase kinase-3 beta GSK3B 0.0044
6832 Serine/threonine-protein kinase SRPK2 SRPK2 0.0039
1714 Mitogen-activated protein kinase 3 MAPK3 0.0034
6893 Calcium/calmodulin-dependent protein kinase type II gamma chain CAMK2G 0.0032
6824 Tyrosine-protein kinase Lyn LYN 0.003
2599 Tyrosine-protein kinase HCK HCK 0.0028
3950 Cell division protein kinase 9 CDK9 0.0028
3968 Cell division protein kinase 8 CDK8 0.0028
2473 Tyrosine-protein kinase CSK CSK 0.0026
2398 Tyrosine-protein kinase ZAP-70 ZAP70 0.0026
3482 Cell division protein kinase 7 CDK7 0.0024
990 Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 0.0024
4341 Beta crystallin B1 CRYBB1 0.0024
4340 Hypothetical conserved protein GK2698 0.0024
6484 Hypothetical conserved protein TT_C0834 0.0024
4339 Sucrose phosphorylase sucP 0.0024
1434 Protein DJ-1 PARK7 0.0024
4336 Glyceraldehyde 3-phosphate dehydrogenase Not Available 0.0024
4436 Glyceraldehyde 3-phosphate dehydrogenase tthHB8IM 0.0024
3955 Cell division protein kinase 6 CDK6 0.0023
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0022
3421 Hydroxyethylthiazole kinase thiM 0.0021
2688 Peptide deformylase def 0.0021
2708 Peptide deformylase def 0.0021
3004 Peptide deformylase def 0.0021
4337 Peptide deformylase def 0.0021
4338 Peptide deformylase def 0.0021
5368 Peptide deformylase def 0.0021
5371 Peptide deformylase def 0.0021
6375 Peptide deformylase def 0.0021
6378 Peptide deformylase def 0.0021
6379 Peptide deformylase def 0.0021
6776 Peptide deformylase def 0.0021
6900 Peptide deformylase def 0.0021
2530 Protein kinase C theta type PRKCQ 0.0021
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.002
3105 M-phase inducer phosphatase 2 CDC25B 0.0019
4343 Alpha-glucosidase aglA 0.0019
2408 Tyrosine-protein kinase SYK SYK 0.0018
3168 Beta-lactamase OXA-1 bla 0.0018
4819 Hydrolase Not Available 0.0018
5249 Hydrolase Not Available 0.0018
5436 Hydrolase Not Available 0.0018
3230 Non-ATP-dependent L-selective hydantoinase lhyD 0.0018
3122 D-hydantoinase Not Available 0.0018
3145 D-hydantoinase hyuA 0.0018
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0017
2840 Beta-lactamase IMP-1 Not Available 0.0017
2404 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PIK3CG 0.0016
3873 Prolyl endopeptidase PREP 0.0015
6928 Prolyl endopeptidase Not Available 0.0015
3237 Beta-lactamase OXA-2 bla 0.0015
3292 Alanine racemase, catabolic dadX 0.0015
3281 Isoaspartyl dipeptidase iadA 0.0015
4264 Alpha-L-fucosidase, putative TM_0306 0.0015
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0015
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0015
844 Epidermal growth factor receptor EGFR 0.0015
1588 Multidrug resistance protein 1 ABCB1 0.0014
2801 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase murE 0.0014
2983 Methylmalonyl-CoA carboxyltransferase 5S subunit Not Available 0.0014
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0014
4549 Endonuclease III HP_0602 0.0013
2646 Dihydroorotase pyrC 0.0013
2717 Folylpolyglutamate synthase fgs 0.0013
1152 Glycogen phosphorylase, muscle form PYGM 0.0013
2340 Beta-lactamase PSE-2 bla 0.0012
2796 Parathion hydrolase opd 0.0012
6539 Parathion hydrolase opd 0.0012
894 Alanine racemase alr 0.0012
2453 Alanine racemase alr 0.0012
2317 UDP-N-acetylmuramoylalanine--D-glutamate ligase murD 0.0011
687 Tyrosine-protein phosphatase non-receptor type 1 PTPN1 0.0011
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0008
4512 Cytochrome P450 3A4 CYP3A4 0.0007
↑