DT-Web

DB07692 - 1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine


Identification
Name 1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine
Accession Number DB07692
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 460.472
Groups experimental
Monoisotopic Weight 460.057434108
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Pyruvate kinase isozymes M1/M2
Name Pyruvate kinase isozymes M1/M2
Gene Name PKM2
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.2592

Predictions


Id Partner name Gene Name Score
52 Pyruvate kinase isozymes R/L PKLR 0.0452
2904 Phosphatase yniC yniC 0.0349
3676 Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive aroG 0.0303
3192 Glucosamine-6-phosphate deaminase 1 nagB 0.0303
3309 6-phosphofructokinase pfkA 0.0301
3467 Methylglyoxal synthase mgsA 0.0281
2314 Triosephosphate isomerase TPI 0.0244
3417 Triosephosphate isomerase tpiA 0.0244
3443 Triosephosphate isomerase tpiA 0.0244
6346 Triosephosphate isomerase TPI1 0.0244
218 Monocarboxylate transporter 5 SLC16A4 0.0173
397 Monocarboxylate transporter 3 SLC16A8 0.0173
429 Monocarboxylate transporter 6 SLC16A5 0.0173
195 Monocarboxylate transporter 7 SLC16A6 0.0173
771 Pyruvate carboxylase, mitochondrial PC 0.0151
110 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.0143
500 Monocarboxylate transporter 4 SLC16A3 0.0138
489 Monocarboxylate transporter 2 SLC16A7 0.0138
114 Alanine--glyoxylate aminotransferase 2, mitochondrial AGXT2 0.0126
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0117
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0116
199 Monocarboxylate transporter 8 SLC16A2 0.0115
738 Monocarboxylate transporter 1 SLC16A1 0.0105
6151 Monocarboxylate transporter 10 SLC16A10 0.0091
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