DT-Web

DB07397 - (5S)-5-(2-amino-2-oxoethyl)-4-oxo-N-[(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)methyl]-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidine-2-carboxamide


Identification
Name (5S)-5-(2-amino-2-oxoethyl)-4-oxo-N-[(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)methyl]-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidine-2-carboxamide
Accession Number DB07397
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 467.498
Groups experimental
Monoisotopic Weight 467.126339497
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Neutrophil collagenase
Name Neutrophil collagenase
Gene Name MMP8
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.6373

Predictions


Id Partner name Gene Name Score
1167 Interstitial collagenase MMP1 0.0705
2970 Matrix metalloproteinase-16 MMP16 0.0345
6230 A disintegrin and metalloproteinase with thrombospondin motifs 5 ADAMTS5 0.0307
2203 Macrophage metalloelastase MMP12 0.026
6374 Disintegrin and metalloproteinase domain-containing protein 28 ADAM28 0.0259
6195 Matrix metalloproteinase-20 MMP20 0.0062
6188 Stromelysin-2 MMP10 0.0061
6190 Stromelysin-3 MMP11 0.0061
6189 Matrilysin MMP7 0.0058
6200 Matrix metalloproteinase-26 MMP26 0.0058
6201 Matrix metalloproteinase-27 MMP27 0.0058
6198 Matrix metalloproteinase-24 MMP24 0.0058
6191 Matrix metalloproteinase-14 MMP14 0.0058
6192 Matrix metalloproteinase-15 MMP15 0.0058
6199 Matrix metalloproteinase-25 MMP25 0.0058
6197 Matrix metalloproteinase-23 MMP23A 0.0058
6202 Matrix metalloproteinase-28 MMP28 0.0058
6194 Matrix metalloproteinase-19 MMP19 0.0058
6196 Matrix metalloproteinase-21 MMP21 0.0058
6193 Matrix metalloproteinase-17 MMP17 0.0058
1330 Collagenase 3 MMP13 0.0048
65 Matrix metalloproteinase-9 Not Available 0.0045
707 72 kDa type IV collagenase MMP2 0.0045
1926 Stromelysin-1 MMP3 0.0044
↑