DT-Web

DB07207 - 2-(4-HYDROXY-5-PHENYL-1H-PYRAZOL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE


Identification
Name 2-(4-HYDROXY-5-PHENYL-1H-PYRAZOL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE
Accession Number DB07207
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 318.3327
Groups experimental
Monoisotopic Weight 318.1229091
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Coagulation factor VII
Name Coagulation factor VII
Gene Name F7
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.7371
Tissue factor
Name Tissue factor
Gene Name F3
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.1214

Predictions


Id Partner name Gene Name Score
1334 Tissue factor pathway inhibitor TFPI 0.1154
448 Vitamin K-dependent gamma-carboxylase GGCX 0.1004
3851 Serine protease hepsin HPN 0.0902
239 Coagulation factor X F10 0.0817
54 Prothrombin F2 0.0621
19 Coagulation factor VIII F8 0.029
3831 Low-density lipoprotein receptor-related protein 1 LRP1 0.0267
1547 Coagulation factor XI F11 0.0209
400 Coagulation factor IX F9 0.0088
5461 Coagulation factor IX F9 0.0088
4081 Vitamin K epoxide reductase complex subunit 1-like protein 1 VKORC1L1 0.0086
604 Vitamin K-dependent protein Z PROZ 0.0086
422 Vitamin K-dependent protein C PROC 0.0075
1245 Vitamin K-dependent protein S PROS1 0.0075
798 Osteocalcin BGLAP 0.0074
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0062
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0058
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0057
3917 Methylenetetrahydrofolate reductase MTHFR 0.0052
6020 Aldehyde oxidase AOX1 0.005
3947 Xanthine dehydrogenase/oxidase XDH 0.0047
5718 Cytochrome P450 2A6 CYP2A6 0.0036
6024 Cytochrome P450 1A1 CYP1A1 0.0034
6013 Cytochrome P450 2E1 CYP2E1 0.0033
4200 Cytochrome P450 1A2 CYP1A2 0.0028
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