DT-Web

DB06854 - 2-(2-HYDROXY-BIPHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE


Identification
Name 2-(2-HYDROXY-BIPHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE
Accession Number DB06854
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 328.3672
Groups experimental
Monoisotopic Weight 328.132411154
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Prothrombin
Name Prothrombin
Gene Name F2
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.6376
Urokinase-type plasminogen activator
Name Urokinase-type plasminogen activator
Gene Name PLAU
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.5561

Predictions


Id Partner name Gene Name Score
3176 Trypsin-1 PRSS1 0.2216
239 Coagulation factor X F10 0.0394
3851 Serine protease hepsin HPN 0.0246
3011 Suppressor of tumorigenicity protein 14 ST14 0.019
369 Coagulation factor VII F7 0.0173
3119 Fimbrial protein pilE1 0.0168
6564 Prephenate dehydrogenase tyrA 0.0122
6240 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1 0.0122
3833 Plasma serine protease inhibitor SERPINA5 0.0121
2889 Kallikrein-6 KLK6 0.0115
2947 Trypsin sprT 0.0114
3834 Nidogen-1 NID1 0.0104
2331 HTH-type transcriptional regulator qacR qacR 0.01
6461 HTH-type transcriptional regulator qacR qacR 0.01
3211 3,2-trans-enoyl-CoA isomerase, mitochondrial DCI 0.0099
4814 Copper transport protein ATOX1 ATOX1 0.0099
6828 TetR family transcriptional repressor LfrR lfrR 0.0095
256 Tyrosyl-tRNA synthetase, cytoplasmic YARS 0.0093
3384 Macrophage migration inhibitory factor MIF 0.009
1349 Plasminogen activator inhibitor 2 SERPINB2 0.009
267 Plasminogen activator inhibitor 1 SERPINE1 0.009
19 Coagulation factor VIII F8 0.0083
1757 Myeloperoxidase MPO 0.0083
798 Osteocalcin BGLAP 0.008
2886 Trypsin-3 PRSS3 0.0075
791 Urokinase plasminogen activator surface receptor PLAUR 0.0075
3831 Low-density lipoprotein receptor-related protein 1 LRP1 0.0075
1244 Low-density lipoprotein receptor-related protein 2 LRP2 0.0071
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0064
387 Amiloride-sensitive amine oxidase [copper-containing] ABP1 0.0062
7187 Amiloride-sensitive amine oxidase [copper-containing] ABP1 0.0062
827 Sodium/hydrogen exchanger 1 SLC9A1 0.0062
234 Plasminogen PLG 0.006
2236 Casein kinase II subunit alpha CSNK2A1 0.006
1792 Tissue-type plasminogen activator PLAT 0.006
749 Amiloride-sensitive cation channel 1, neuronal ACCN1 0.0056
550 Amiloride-sensitive sodium channel subunit delta SCNN1D 0.005
27 Amiloride-sensitive sodium channel subunit beta SCNN1B 0.005
552 Amiloride-sensitive sodium channel subunit gamma SCNN1G 0.005
213 Amiloride-sensitive sodium channel subunit alpha SCNN1A 0.005
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0049
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0049
4757 Cytochrome P450 2C9 CYP2C9 0.0048
4165 P2Y purinoceptor 2 P2RY2 0.0047
400 Coagulation factor IX F9 0.0039
5461 Coagulation factor IX F9 0.0039
1547 Coagulation factor XI F11 0.0039
2654 Complement control protein C3L 0.0037
1959 Platelet factor 4 PF4 0.0035
3865 Serpin B6 SERPINB6 0.0035
1986 Ceruloplasmin CP 0.0035
1245 Vitamin K-dependent protein S PROS1 0.0035
4118 Cytochrome P450 3A5 CYP3A5 0.0035
430 Follicle-stimulating hormone receptor FSHR 0.0034
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0034
422 Vitamin K-dependent protein C PROC 0.0033
3842 Multiple coagulation factor deficiency protein 2 MCFD2 0.0033
3841 ERGIC-53 protein LMAN1 0.0033
3840 Asialoglycoprotein receptor 2 ASGR2 0.0033
1847 78 kDa glucose-regulated protein HSPA5 0.0033
1635 von Willebrand factor VWF 0.0033
5455 Arylsulfatase A ARSA 0.0032
833 Organic cation/carnitine transporter 1 SLC22A4 0.0031
4604 Liver carboxylesterase 1 CES1 0.0031
2072 Endothelial protein C receptor PROCR 0.0031
46 Coagulation factor V F5 0.0031
814 Ryanodine receptor 1 RYR1 0.0029
4512 Cytochrome P450 3A4 CYP3A4 0.0028
1516 Calnexin CANX 0.0028
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0027
2981 Phospholipase A2, membrane associated PLA2G2A 0.0026
2021 Thrombomodulin THBD 0.0026
6144 Solute carrier family 22 member 2 SLC22A2 0.0026
6145 Solute carrier family 22 member 1 SLC22A1 0.0026
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0025
3830 Calreticulin CALR 0.0023
3839 Phytanoyl-CoA dioxygenase, peroxisomal PHYH 0.0023
723 Cytosolic phospholipase A2 PLA2G4A 0.0023
1588 Multidrug resistance protein 1 ABCB1 0.0016
604 Vitamin K-dependent protein Z PROZ 0.0014
4081 Vitamin K epoxide reductase complex subunit 1-like protein 1 VKORC1L1 0.0014
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.001
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.001
3917 Methylenetetrahydrofolate reductase MTHFR 0.0009
6020 Aldehyde oxidase AOX1 0.0009
3947 Xanthine dehydrogenase/oxidase XDH 0.0008
5718 Cytochrome P450 2A6 CYP2A6 0.0006
6024 Cytochrome P450 1A1 CYP1A1 0.0006
6013 Cytochrome P450 2E1 CYP2E1 0.0006
4200 Cytochrome P450 1A2 CYP1A2 0.0005
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