DT-Web

DB06847 - 5-[(3S)-3-(2-methoxybiphenyl-4-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine


Identification
Name 5-[(3S)-3-(2-methoxybiphenyl-4-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
Accession Number DB06847
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 358.4363
Groups experimental
Monoisotopic Weight 358.179361346
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Trimethoprim-sensitive dihydrofolate reductase
Name Trimethoprim-sensitive dihydrofolate reductase
Gene Name dfrB
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.3

Predictions


Id Partner name Gene Name Score
365 Dihydrofolate reductase DHFR 0.276
2381 Dihydrofolate reductase DFR1 0.276
2833 Dihydrofolate reductase Not Available 0.276
2931 Dihydrofolate reductase folA 0.276
3544 Dihydrofolate reductase folA 0.276
3682 Dihydrofolate reductase folA 0.276
6642 Dihydrofolate reductase folA 0.276
6756 Dihydrofolate reductase dfrA 0.276
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