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DB04787 - Tanaproget


Identification
Name Tanaproget
Accession Number DB04787
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 297.375
Groups experimental
Monoisotopic Weight 297.093582807
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Progesterone receptor
Name Progesterone receptor
Gene Name PGR
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.5685

Predictions


Id Partner name Gene Name Score
136 Estrogen receptor ESR1 0.1298
2202 Steryl-sulfatase STS 0.0552
146 Androgen receptor AR 0.0486
4512 Cytochrome P450 3A4 CYP3A4 0.0474
871 Glucocorticoid receptor NR3C1 0.0359
737 Mineralocorticoid receptor NR3C2 0.0293
1588 Multidrug resistance protein 1 ABCB1 0.0218
6241 Nuclear receptor coactivator 2 NCOA2 0.0206
756 Sex hormone-binding globulin SHBG 0.0195
6107 Cytochrome P450 3A7 CYP3A7 0.0173
596 3-oxo-5-alpha-steroid 4-dehydrogenase 1 SRD5A1 0.0172
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0167
4118 Cytochrome P450 3A5 CYP3A5 0.0163
3811 Cytochrome P450 19A1 CYP19A1 0.0159
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0151
1649 Small inducible cytokine A2 CCL2 0.0127
226 Gonadotropin-releasing hormone receptor GNRHR 0.0103
3923 Cholinesterase BCHE 0.0094
290 Prostaglandin G/H synthase 2 PTGS2 0.0091
723 Cytosolic phospholipase A2 PLA2G4A 0.0091
232 Corticosteroid-binding globulin SERPINA6 0.0088
862 Multidrug resistance-associated protein 1 ABCC1 0.0082
4924 Cytochrome P450 2C8 CYP2C8 0.008
4757 Cytochrome P450 2C9 CYP2C9 0.0073
6016 Cytochrome P450 2C19 CYP2C19 0.0062
4119 Cytochrome P450 2D6 CYP2D6 0.0057
587 Serum albumin ALB 0.0051
380 Cytochrome P450 17A1 CYP17A1 0.0036
6141 Sodium/bile acid cotransporter SLC10A1 0.003
6147 Solute carrier family 22 member 3 SLC22A3 0.0025
1898 Cytochrome P450 1B1 CYP1B1 0.0025
776 Bile salt export pump ABCB11 0.0025
6144 Solute carrier family 22 member 2 SLC22A2 0.0021
6145 Solute carrier family 22 member 1 SLC22A1 0.0021
5718 Cytochrome P450 2A6 CYP2A6 0.002
6024 Cytochrome P450 1A1 CYP1A1 0.002
4200 Cytochrome P450 1A2 CYP1A2 0.0016
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