DT-Web

DB04483 - 2-Deoxy-2-Fluoro-Beta-D-Mannose


Identification
Name 2-Deoxy-2-Fluoro-Beta-D-Mannose
Accession Number DB04483 (EXPT02121)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 182.1469
Groups experimental
Monoisotopic Weight 182.059051667
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Mannan endo-1,4-beta-mannosidase
Name Mannan endo-1,4-beta-mannosidase
Gene Name manA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.04

Predictions


Id Partner name Gene Name Score
4784 Beta-mannosidase manB 0.0312
6695 Beta-mannosidase BT_0458 0.0312
2998 Sialic acid-binding Ig-like lectin 7 SIGLEC7 0.03
4787 Envelope glycoprotein gp160 env 0.0283
4820 Envelope glycoprotein gp160 env 0.0283
5727 Envelope glycoprotein gp160 env 0.0283
2297 Genome polyprotein Not Available 0.0272
2322 Genome polyprotein Not Available 0.0272
2694 Genome polyprotein Not Available 0.0272
2719 Genome polyprotein Not Available 0.0272
2860 Genome polyprotein Not Available 0.0272
2928 Genome polyprotein Not Available 0.0272
3160 Genome polyprotein Not Available 0.0272
3260 Genome polyprotein Not Available 0.0272
4783 Genome polyprotein Not Available 0.0272
5726 Genome polyprotein Not Available 0.0272
5779 Genome polyprotein Not Available 0.0272
5867 Genome polyprotein Not Available 0.0272
6253 Genome polyprotein Not Available 0.0272
6301 Genome polyprotein Not Available 0.0272
6380 Genome polyprotein Not Available 0.0272
6381 Genome polyprotein Not Available 0.0272
6437 Genome polyprotein Not Available 0.0272
6520 Genome polyprotein Not Available 0.0272
6521 Genome polyprotein Not Available 0.0272
6652 Genome polyprotein Not Available 0.0272
6734 Genome polyprotein Not Available 0.0272
6735 Genome polyprotein Not Available 0.0272
6736 Genome polyprotein Not Available 0.0272
6737 Genome polyprotein Not Available 0.0272
6738 Genome polyprotein Not Available 0.0272
6739 Genome polyprotein Not Available 0.0272
6744 Genome polyprotein Not Available 0.0272
6748 Genome polyprotein Not Available 0.0272
6894 Genome polyprotein Not Available 0.0272
6898 Genome polyprotein Not Available 0.0272
3437 Eosinophil lysophospholipase CLC 0.0251
2207 Rhodopsin RHO 0.0212
6131 Carbonic anhydrase 14 CA14 0.0206
4785 Ig gamma-1 chain C region IGHG1 0.0194
3923 Cholinesterase BCHE 0.0172
20 Prostaglandin G/H synthase 1 PTGS1 0.012
3781 Thiol:disulfide interchange protein dsbC precursor dsbC 0.0113
5443 UPF0189 protein ymdB ymdB 0.0113
5440 UPF0067 protein yebR yebR 0.0113
5439 33 kDa chaperonin hslO 0.0113
5449 Hypothetical gliding protein mglB 0.0113
332 Beta-lactamase blaZ 0.0113
2478 Beta-lactamase ampC 0.0113
2613 Beta-lactamase ampC 0.0113
2635 Beta-lactamase ampC 0.0113
2700 Beta-lactamase penP 0.0113
5445 Beta-lactamase blaB 0.0113
6019 Beta-lactamase SHV-7 0.0113
6701 Beta-lactamase cphA 0.0113
5448 Ribonuclease Z rnz 0.0113
5446 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase HI_1679 0.0113
2720 Copper-containing nitrite reductase nirK 0.0113
4705 Manganese catalase Not Available 0.0113
5447 Lethal(3)malignant brain tumor-like protein L3MBTL1 0.0113
5454 Internalin-A inlA 0.0113
2714 Chorismate mutase aroH 0.0098
4611 Chorismate mutase aroG 0.0098
3274 Hydroxylamine reductase hcp 0.0098
4804 Hydroxylamine reductase hcp 0.0098
4498 Ornithine cyclodeaminase PP3533 0.0098
4771 Dissimilatory copper-containing nitrite reductase nir 0.0098
5450 Prolyl endopeptidase Pep pep 0.0098
3356 Diaminopimelate decarboxylase lysA 0.0098
3399 Limonene-1,2-epoxide hydrolase limA 0.0091
3736 Glyceraldehyde-3-phosphate dehydrogenase A gapA 0.0091
3697 Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase glmU 0.0091
3462 Tyrosine-protein kinase transforming protein Abl ABL 0.009
5180 L(+)-mandelate dehydrogenase mdlB 0.0085
3500 Putative family 31 glucosidase yicI yicI 0.0085
597 Dihydropteridine reductase QDPR 0.0083
577 Argininosuccinate lyase ASL 0.0082
4608 Putative cytochrome P450 SCO1207 0.0082
4963 Putative cytochrome P450 SCO2884 0.0082
6254 Putative cytochrome P450 SCO6998 0.0082
1615 Chymase CMA1 0.0082
2597 Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] glmS 0.0079
365 Dihydrofolate reductase DHFR 0.0077
2381 Dihydrofolate reductase DFR1 0.0077
2833 Dihydrofolate reductase Not Available 0.0077
2931 Dihydrofolate reductase folA 0.0077
3544 Dihydrofolate reductase folA 0.0077
3682 Dihydrofolate reductase folA 0.0077
6642 Dihydrofolate reductase folA 0.0077
6756 Dihydrofolate reductase dfrA 0.0077
287 Beta-1,4-galactosyltransferase 1 B4GALT1 0.0076
4878 Glycoprotein hormones alpha chain CGA 0.0062
1052 Cytotoxic T-lymphocyte protein 4 CTLA4 0.0062
1072 Granzyme B GZMB 0.0062
4877 Beta-mannanase man 0.0062
4871 Endo-beta-N-acetylglucosaminidase F3 endOF3 0.0062
4850 Beta-2-glycoprotein 1 APOH 0.0062
757 Fusion glycoprotein F0 F 0.0062
4875 Fusion glycoprotein F0 F 0.0062
4880 Membrane cofactor protein CD46 0.0062
4889 Ig epsilon chain C region IGHE 0.0062
4869 Major capsid protein A430L 0.0062
4852 Reticulon-4 receptor RTN4R 0.0062
4845 ADAM 33 ADAM33 0.0062
4882 Dipeptidyl aminopeptidase-like protein 6 DPP6 0.0062
4721 Beta-1,4-mannanase manA 0.0062
1354 Beta-glucuronidase GUSB 0.0062
442 Envelope glycoprotein gp41 0.0062
4859 Envelope glycoprotein env 0.0062
4856 CD209 antigen CD209 0.0062
4189 Alpha-galactosidase A GLA 0.0062
1563 Platelet glycoprotein Ib alpha chain GP1BA 0.0062
3352 Structural polyprotein Not Available 0.0061
3628 Structural polyprotein Not Available 0.0061
4892 Structural polyprotein Not Available 0.0061
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0061
904 Glutathione S-transferase P GSTP1 0.0055
1184 Interferon beta IFNB1 0.0054
6858 Inactive carboxylesterase 4 CES1P1 0.0054
1379 Interleukin-12 subunit beta IL12B 0.0054
793 T-cell surface antigen CD2 CD2 0.0054
4861 Interleukin-6 receptor alpha chain IL6R 0.0054
4857 Zinc-alpha-2-glycoprotein AZGP1 0.0054
119 Carcinoembryonic antigen-related cell adhesion molecule 1 CEACAM1 0.0054
4193 Atrial natriuretic peptide clearance receptor NPR3 0.0054
4890 Hemagglutinin HA 0.0054
6566 Hemagglutinin Not Available 0.0054
3837 Cytokine receptor common beta chain CSF2RB 0.0054
3444 Cyanovirin-N Not Available 0.0049
3140 Hemagglutinin-neuraminidase HN 0.0049
3609 Hemagglutinin-neuraminidase HN 0.0049
1859 Prostatic acid phosphatase ACPP 0.0049
3258 Mannosyl-oligosaccharide alpha-1,2-mannosidase MSDC 0.0049
6120 Cation-independent mannose-6-phosphate receptor IGF2R 0.0049
4666 Fucose-binding lectin PA-IIL lecB 0.0047
2372 Bifunctional tail protein 9 0.0047
474 Acetylcholinesterase ACHE 0.0047
554 Low-density lipoprotein receptor LDLR 0.0046
852 Heparin cofactor 2 SERPIND1 0.0045
18 High affinity immunoglobulin epsilon receptor subunit alpha FCER1A 0.0045
2577 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase MAN1B1 0.0045
64 Neuraminidase NA 0.0043
641 Neuraminidase NA 0.0043
2676 Neuraminidase NA 0.0043
3026 Neuraminidase NA 0.0043
3519 Neuraminidase NA 0.0043
6007 Neuraminidase NA 0.0043
1439 Lactotransferrin LTF 0.0042
595 Fibrinogen alpha chain FGA 0.0041
1243 Cathepsin D CTSD 0.0041
1782 Neutrophil gelatinase-associated lipocalin LCN2 0.004
2430 Chondroitinase B cslB 0.004
958 Insulin-like growth factor 1 receptor IGF1R 0.004
6307 Ig gamma-2 chain C region IGHG2 0.0039
2581 Chondroitinase AC cslA 0.0039
6847 Lactase-phlorizin hydrolase LCT 0.0038
6500 Phospholipase A2 PLA2G1B 0.0037
309 Antithrombin-III SERPINC1 0.0035
3814 Complement C1r subcomponent C1R 0.0034
76 Nitric-oxide synthase, brain NOS1 0.0031
4604 Liver carboxylesterase 1 CES1 0.0028
952 Dipeptidyl peptidase 4 DPP4 0.0028
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