DT-Web

DB04342 - 7-((Carboxy(4-Hydroxyphenyl)Acetyl)Amino)-7-Methoxy-(3-((1-Methyl-1h-Tetrazol-5-Yl)Thio)Methyl)-8-Oxo-5-Oxa-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid


Identification
Name 7-((Carboxy(4-Hydroxyphenyl)Acetyl)Amino)-7-Methoxy-(3-((1-Methyl-1h-Tetrazol-5-Yl)Thio)Methyl)-8-Oxo-5-Oxa-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
Accession Number DB04342 (EXPT02261)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 520.473
Groups experimental
Monoisotopic Weight 520.101246958
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Beta-lactamase PSE-2
Name Beta-lactamase PSE-2
Gene Name bla
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.8307

Predictions


Id Partner name Gene Name Score
6643 Beta-lactamase AmpC ampC 0.1694
819 Penicillin-binding protein 4 dacB 0.1365
332 Beta-lactamase blaZ 0.1159
2478 Beta-lactamase ampC 0.1159
2613 Beta-lactamase ampC 0.1159
2635 Beta-lactamase ampC 0.1159
2700 Beta-lactamase penP 0.1159
5445 Beta-lactamase blaB 0.1159
6019 Beta-lactamase SHV-7 0.1159
6701 Beta-lactamase cphA 0.1159
3168 Beta-lactamase OXA-1 bla 0.0267
4819 Hydrolase Not Available 0.0267
5249 Hydrolase Not Available 0.0267
5436 Hydrolase Not Available 0.0267
3230 Non-ATP-dependent L-selective hydantoinase lhyD 0.0267
3122 D-hydantoinase Not Available 0.0267
3145 D-hydantoinase hyuA 0.0267
4264 Alpha-L-fucosidase, putative TM_0306 0.0234
3237 Beta-lactamase OXA-2 bla 0.0233
3292 Alanine racemase, catabolic dadX 0.0233
3281 Isoaspartyl dipeptidase iadA 0.0232
2983 Methylmalonyl-CoA carboxyltransferase 5S subunit Not Available 0.0215
2801 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase murE 0.0214
2646 Dihydroorotase pyrC 0.0202
4549 Endonuclease III HP_0602 0.0202
2717 Folylpolyglutamate synthase fgs 0.0193
2796 Parathion hydrolase opd 0.018
6539 Parathion hydrolase opd 0.018
894 Alanine racemase alr 0.0176
2453 Alanine racemase alr 0.0176
2317 UDP-N-acetylmuramoylalanine--D-glutamate ligase murD 0.0174
2240 Cell division protein kinase 2 CDK2 0.01
↑