DT-Web

DB04249 - Zinc Substituted Heme C


Identification
Name Zinc Substituted Heme C
Accession Number DB04249 (EXPT01728)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 628.067
Groups experimental
Monoisotopic Weight 626.187152174
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Cytochrome c
Name Cytochrome c
Gene Name CYCS
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.8341

Predictions


Id Partner name Gene Name Score
465 Calmodulin CALM1 0.0745
20 Prostaglandin G/H synthase 1 PTGS1 0.0542
1654 Interleukin-1 beta IL1B 0.0192
494 Caspase-1 CASP1 0.0187
2077 Caspase-3 CASP3 0.0162
4923 Cytochrome c3 DvMF_2499 0.0159
4945 Cytochrome c3 Not Available 0.0159
4949 Cytochrome c3 DVU_3171 0.0159
4968 Cytochrome c3 cytc3 0.0159
4997 Cytochrome c3 SO_2727 0.0159
5219 Cytochrome c3 cyd 0.0159
4948 Cytochrome c-553 Not Available 0.0159
4902 Nine-heme cytochrome c Ddes_2038 0.0159
3189 High-molecular-weight cytochrome c hmcA 0.0159
183 Vascular endothelial growth factor A VEGFA 0.0156
3152 Cytochrome c'' cycA 0.0148
5221 Cytochrome c3, 13 kDa Not Available 0.0148
5220 Split-Soret cytochrome c Ddes_2150 0.0148
3700 Cytochrome c-552 precursor nrfA 0.0148
65 Matrix metalloproteinase-9 Not Available 0.0147
4386 Hemoglobin-like protein HbN glbN 0.0145
22 30S ribosomal protein S4 rpsD 0.0138
6714 30S ribosomal protein S4 rpsD 0.0138
3221 Cytochrome c4 cc4 0.0136
275 Arachidonate 5-lipoxygenase ALOX5 0.0131
140 30S ribosomal protein S9 rpsI 0.0131
6719 30S ribosomal protein S9 rpsI 0.0131
6725 30S ribosomal protein S9 rpsI 0.0131
3127 Nitrite reductase nirS 0.0129
3284 Nitrite reductase nirS 0.0129
3405 Quinohaemoprotein ethanol dehydrogenase type-1 qheDH 0.0112
1024 Solute carrier family 22 member 11 SLC22A11 0.0096
6143 Solute carrier family 22 member 7 SLC22A7 0.0093
6142 Solute carrier family 22 member 8 SLC22A8 0.0084
1729 Solute carrier family 22 member 6 SLC22A6 0.0076
4757 Cytochrome P450 2C9 CYP2C9 0.0043
4905 Cytochrome c2 Not Available 0.0031
4939 Cytochrome c2 cycA 0.0031
4964 Cytochrome c2 cycA 0.0031
4979 Cytochrome c2 cycA 0.0031
6673 Cytochrome c2 cycA 0.0031
4934 Cytochrome c-551 nirM 0.0031
5218 Cytochrome c-551 nirM 0.0031
4936 Cytochrome c2 iso-2 Not Available 0.0031
4916 Cyanoglobin glbN 0.0031
4998 Hemoglobin-like protein yjbI yjbI 0.0031
4943 Cytochrome c6 petJ 0.0031
4981 Iron-starvation protein PigA pigA 0.0031
4994 Hemoglobin-like protein HbO glbO 0.0031
4915 Cytochrome c-550 psbV 0.0031
4959 Cytochrome c-550 psbV 0.0031
5216 Cytochrome c-550 psbV 0.0031
4925 Cytochrome c-type protein SHP shp 0.0031
4999 Cytochrome P450 165B3 CYP165B3 0.0031
4947 Bacterial hemoglobin vhb 0.0031
4975 Cytochrome c-556 RPA3973 0.0031
4942 Diheme cytochrome c napB napB 0.0031
4984 Neuroglobin NGB 0.0031
3116 Bacterioferritin bfr 0.0031
4906 Bacterioferritin bfr 0.0031
4965 Bacterioferritin bfr 0.0031
4935 Cytochrome c-554 cycA1 0.0031
4937 Cytochrome oxidase subunit II rcoxA 0.0031
4961 Hemophore HasA hasA 0.0031
4910 Cytoglobin CYGB 0.0031
4904 Cytochrome c family protein GSU1996 0.0031
4907 Cytochrome c-L moxG 0.0031
6865 Cytochrome c-L moxG 0.0031
4954 Soluble cytochrome b558 Not Available 0.0031
4909 CooA protein cooA 0.0031
5000 HemO hemO 0.0031
4971 Nonaheme cytochrome c hmcA 0.0031
4931 Cytochrome P450 167A1 CYP167A1 0.0031
644 Heme oxygenase 2 HMOX2 0.0031
4982 Heme oxygenase 2 pbsA2 0.0031
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0031
4922 Cytochrome c, putative SO_4144 0.0031
4989 Cytochrome c551 peroxidase ccp 0.0031
5222 Cytochrome c551 peroxidase ccpA 0.0031
4976 Apocytochrome f petA 0.0031
6407 Apocytochrome f petA 0.0031
4903 Methyl-accepting chemotaxis protein Tar4 0.0031
4972 P450cin cinA 0.0031
4764 Cytochrome P450 165C4 CYP165C4 0.0031
4960 Putative cytochrome P450-family protein SCO7417 0.0031
4926 Heme-based aerotactic transducer hemAT hemAT 0.0031
4952 Catalase/peroxidase katA 0.0031
4993 Hydroxylamine oxidoreductase hao1 0.0031
3093 Catalase HPII katE 0.0031
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0031
4990 PpcA ppcA 0.0027
4920 Peroxidase/catalase katG 0.0027
3375 Acidic cytochrome c3 Not Available 0.0026
2119 Cytochrome b5 CYB5A 0.0026
4813 Heme oxygenase hmuO 0.0026
5769 Heme oxygenase Not Available 0.0026
4385 Cytochrome c' Not Available 0.0026
4967 Cytochrome c' cycA 0.0026
5038 Cytochrome c' Not Available 0.0026
5223 Cytochrome c' cycP 0.0026
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0026
3570 Cytochrome P450 152A1 cypC 0.0026
4988 Sulfite oxidase, mitochondrial SUOX 0.0026
4037 Hypothetical protein GPX1 0.0026
4297 Hypothetical protein SP_1951 0.0026
4521 Hypothetical protein BC_2969 0.0026
4540 Hypothetical protein TM_1070 0.0026
4555 Hypothetical protein MT1739 0.0026
4569 Hypothetical protein mshD 0.0026
4578 Hypothetical protein PA3270 0.0026
4747 Hypothetical protein PA3967 0.0026
5177 Hypothetical protein TM_0096 0.0026
5194 Hypothetical protein PA1204 0.0026
5240 Hypothetical protein Rv2991 0.0026
5370 Hypothetical protein TM_1158 0.0026
5710 Hypothetical protein Tb927.5.1360 0.0026
2915 Sensor protein fixL fixL 0.0026
4944 Sensor protein fixL fixL 0.0026
4992 Cytochrome c peroxidase Not Available 0.0026
4289 Cytochrome P450 TT_P0059 0.0026
6262 Cytochrome P450 staP 0.0026
3670 Soluble cytochrome b562 precursor cybC 0.0024
3291 Cytochrome c-552 cycA 0.0024
4927 Cytochrome c-552 nrfA 0.0024
4938 Cytochrome c-552 cycA 0.0024
4953 Cytochrome c-552 nrfA 0.0024
5217 Cytochrome c-552 cycM 0.0024
3411 Cytochrome P450 121 cyp121 0.0024
2617 Nitric oxide synthase oxygenase nos 0.0024
2701 Nitric oxide synthase oxygenase nos 0.0024
3102 Flavohemoprotein hmp 0.0024
4969 Flavohemoprotein hmp 0.0024
2230 Catalase CAT 0.0023
3249 Catalase katA 0.0023
3625 Catalase katA 0.0023
4539 Catalase katA 0.0023
4941 Catalase katB 0.0023
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0023
4608 Putative cytochrome P450 SCO1207 0.0022
4963 Putative cytochrome P450 SCO2884 0.0022
6254 Putative cytochrome P450 SCO6998 0.0022
605 Fumarate reductase flavoprotein subunit frdA 0.0021
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0021
3673 Fumarate reductase flavoprotein subunit fccA 0.0021
4912 Fumarate reductase flavoprotein subunit ifcA 0.0021
6549 Fumarate reductase flavoprotein subunit frdA 0.0021
2972 6-deoxyerythronolide B hydroxylase eryF 0.0021
260 Cytochrome P450 51 ERG11 0.002
761 Cytochrome P450 51 ERG11 0.002
3163 Cytochrome P450 51 cyp51 0.002
518 Peroxidase/catalase T katG 0.002
693 Hemoglobin subunit beta HBB 0.0019
6268 Hydroxyacid oxidase 1 HAO1 0.0019
810 Heme oxygenase 1 HMOX1 0.0018
3391 Heme oxygenase 1 pbsA1 0.0018
358 Cystathionine beta-synthase CBS 0.0017
2298 Cytochrome P450-cam camC 0.0016
76 Nitric-oxide synthase, brain NOS1 0.0015
7 Nitric oxide synthase, inducible NOS2 0.0014
291 Nitric-oxide synthase, endothelial NOS3 0.0014
6106 Cytochrome P450 2C18 CYP2C18 0.0011
290 Prostaglandin G/H synthase 2 PTGS2 0.001
587 Serum albumin ALB 0.0009
6030 Cytochrome P450 2B6 CYP2B6 0.0009
4924 Cytochrome P450 2C8 CYP2C8 0.0008
4512 Cytochrome P450 3A4 CYP3A4 0.0006
↑