DT-Web

DB04016 - 2-[3-({Methyl[1-(2-Naphthoyl)Piperidin-4-Yl]Amino}Carbonyl)-2-Naphthyl]-1-(1-Naphthyl)-2-Oxoethylphosphonic Acid


Identification
Name 2-[3-({Methyl[1-(2-Naphthoyl)Piperidin-4-Yl]Amino}Carbonyl)-2-Naphthyl]-1-(1-Naphthyl)-2-Oxoethylphosphonic Acid
Accession Number DB04016 (EXPT02424)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 670.6895
Groups experimental
Monoisotopic Weight 670.223273374
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Cathepsin G
Name Cathepsin G
Gene Name CTSG
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.7069
Chymase
Name Chymase
Gene Name CMA1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.1697

Predictions


Id Partner name Gene Name Score
864 Gag-Pol polyprotein gag-pol 0.1033
2237 Gag-Pol polyprotein gag-pol 0.1033
2326 Gag-Pol polyprotein gag-pol 0.1033
2451 Gag-Pol polyprotein gag-pol 0.1033
2901 Gag-Pol polyprotein gag-pol 0.1033
3165 Gag-Pol polyprotein gag-pol 0.1033
3722 Gag-Pol polyprotein gag-pol 0.1033
6306 Gag-Pol polyprotein gag-pol 0.1033
6624 Gag-Pol polyprotein gag-pol 0.1033
5212 Carboxylesterase 2 estB 0.0784
5211 Extracellular subtilisin-like serine proteinase Not Available 0.0783
3490 Sigma factor sigB regulation protein rsbQ rsbQ 0.0629
2517 Subtilisin BPN' apr 0.0568
3851 Serine protease hepsin HPN 0.0528
5446 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase HI_1679 0.0131
5449 Hypothetical gliding protein mglB 0.0131
3781 Thiol:disulfide interchange protein dsbC precursor dsbC 0.0131
5439 33 kDa chaperonin hslO 0.0131
332 Beta-lactamase blaZ 0.0131
2478 Beta-lactamase ampC 0.0131
2613 Beta-lactamase ampC 0.0131
2635 Beta-lactamase ampC 0.0131
2700 Beta-lactamase penP 0.0131
5445 Beta-lactamase blaB 0.0131
6019 Beta-lactamase SHV-7 0.0131
6701 Beta-lactamase cphA 0.0131
5448 Ribonuclease Z rnz 0.0131
5443 UPF0189 protein ymdB ymdB 0.0131
5440 UPF0067 protein yebR yebR 0.0131
2720 Copper-containing nitrite reductase nirK 0.0131
4705 Manganese catalase Not Available 0.0131
5454 Internalin-A inlA 0.0131
5447 Lethal(3)malignant brain tumor-like protein L3MBTL1 0.0131
2714 Chorismate mutase aroH 0.0114
4611 Chorismate mutase aroG 0.0114
3274 Hydroxylamine reductase hcp 0.0114
4804 Hydroxylamine reductase hcp 0.0114
3356 Diaminopimelate decarboxylase lysA 0.0114
4498 Ornithine cyclodeaminase PP3533 0.0114
4771 Dissimilatory copper-containing nitrite reductase nir 0.0114
5450 Prolyl endopeptidase Pep pep 0.0114
3399 Limonene-1,2-epoxide hydrolase limA 0.0105
3736 Glyceraldehyde-3-phosphate dehydrogenase A gapA 0.0105
3697 Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase glmU 0.0105
3462 Tyrosine-protein kinase transforming protein Abl ABL 0.0105
5180 L(+)-mandelate dehydrogenase mdlB 0.0099
3500 Putative family 31 glucosidase yicI yicI 0.0099
4608 Putative cytochrome P450 SCO1207 0.0095
4963 Putative cytochrome P450 SCO2884 0.0095
6254 Putative cytochrome P450 SCO6998 0.0095
2597 Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] glmS 0.0091
3480 Mannan endo-1,4-beta-mannosidase manA 0.0091
577 Argininosuccinate lyase ASL 0.0091
597 Dihydropteridine reductase QDPR 0.0091
365 Dihydrofolate reductase DHFR 0.0089
2381 Dihydrofolate reductase DFR1 0.0089
2833 Dihydrofolate reductase Not Available 0.0089
2931 Dihydrofolate reductase folA 0.0089
3544 Dihydrofolate reductase folA 0.0089
3682 Dihydrofolate reductase folA 0.0089
6642 Dihydrofolate reductase folA 0.0089
6756 Dihydrofolate reductase dfrA 0.0089
287 Beta-1,4-galactosyltransferase 1 B4GALT1 0.0085
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.007
904 Glutathione S-transferase P GSTP1 0.0059
474 Acetylcholinesterase ACHE 0.0052
3923 Cholinesterase BCHE 0.0042
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