DT-Web

DB03981 - 1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid


Identification
Name 1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid
Accession Number DB03981 (EXPT03166)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 240.188
Groups experimental
Monoisotopic Weight 239.993987922
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Annexin A5
Name Annexin A5
Gene Name ANXA5
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Heparin-binding growth factor 2
Name Heparin-binding growth factor 2
Gene Name FGF2
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.7944
Heparan sulfate glucosamine 3-O-sulfotransferase 3A1
Name Heparan sulfate glucosamine 3-O-sulfotransferase 3A1
Gene Name HS3ST3A1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.5908

Predictions


Id Partner name Gene Name Score
1943 Hepatocyte growth factor HGF 0.2424
760 Fibroblast growth factor 1 FGF1 0.2354
2654 Complement control protein C3L 0.2231
361 Fibroblast growth factor 4 FGF4 0.0986
3317 Holo-[acyl-carrier-protein] synthase acpS 0.0427
4381 Holo-[acyl-carrier-protein] synthase acpS 0.0427
4380 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 NDST1 0.0427
4382 Sulfotransferase family cytosolic 1B member 1 SULT1B1 0.0427
3812 Fibrinogen beta chain [Contains: Fibrinopeptide B] FGB 0.0407
3813 Fibrinogen gamma chain FGG 0.0407
595 Fibrinogen alpha chain FGA 0.0385
1278 Pro-epidermal growth factor EGF 0.0378
2390 Nonsecretory ribonuclease RNASE2 0.0343
2325 Sulfotransferase family cytosolic 2B member 1 SULT2B1 0.0324
6231 Pepsin A PGA3 0.0319
1353 DNA topoisomerase 1 TOP1 0.0305
3552 DNA topoisomerase 1 topA 0.0305
1050 Bile salt sulfotransferase SULT2A1 0.0278
1275 Estrogen sulfotransferase SULT1E1 0.0259
1192 Sulfotransferase 1A1 SULT1A1 0.0258
5682 Ribonuclease pancreatic RNASE1 0.025
4148 Serine/threonine-protein kinase mTOR MTOR 0.0243
768 FK506-binding protein 1A FKBP1A 0.0204
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0192
587 Serum albumin ALB 0.0143
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0131
6107 Cytochrome P450 3A7 CYP3A7 0.0107
4118 Cytochrome P450 3A5 CYP3A5 0.0102
1588 Multidrug resistance protein 1 ABCB1 0.0094
4512 Cytochrome P450 3A4 CYP3A4 0.0082
5587 Iron(III)-binding periplasmic protein fbpA 0.0074
5598 Glycerol uptake operon antiterminator-related protein TM_1436 0.0073
5577 N5-carboxyaminoimidazole ribonucleotide mutase purE 0.0073
2300 Lysozyme E 0.0073
3633 Lysozyme R 0.0073
5597 Lysozyme 17 0.0073
5600 Pyruvate decarboxylase pdc 0.0073
5591 Complement component C8 gamma chain C8G 0.0073
5582 Regulator of transcription; stringent starvation protein A sspA 0.0073
3792 KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase eda 0.0073
2838 Ribose-5-phosphate isomerase A rpiA 0.0073
2952 Ribose-5-phosphate isomerase A rpiA 0.0073
5595 Ribose-5-phosphate isomerase A rpiA 0.0073
4238 50S ribosomal protein L4 rplD 0.0073
5578 50S ribosomal protein L4 rplD 0.0073
6173 50S ribosomal protein L4 rplD 0.0073
6219 50S ribosomal protein L4 rplD 0.0073
4695 UPF0124 protein yfiH yfiH 0.0073
5590 N utilization substance protein B homolog nusB 0.0073
5593 Transferase Not Available 0.0073
5588 Cell division protein FtsY TM_0570 0.0073
5592 Ribonucleoside-diphosphate reductase subunit beta nrdF 0.0073
5583 RNA 3'-terminal phosphate cyclase rtcA 0.0073
5586 Pleckstrin homology domain-containing family A member 1 PLEKHA1 0.0073
5581 Beta-fructosidase bfrA 0.0073
5060 Intron-associated endonuclease 1 ITEVIR 0.0073
4375 Glutamine synthetase 1 glnA1 0.0073
5575 Short tail fiber protein 12 0.0073
5580 Hexon protein PII 0.0073
5574 Invasin YPTB1668 0.0073
3085 Molybdopterin-guanine dinucleotide biosynthesis protein A mobA 0.0064
5006 RNASE4 protein RNASE4 0.0064
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0064
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0064
4533 Glyoxalase family protein BC_1747 0.0064
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0064
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0064
3132 Tryptophan synthase alpha chain trpA 0.0064
6568 Tryptophan synthase alpha chain trpA 0.0064
3729 Citrate synthase gltA 0.0064
4575 Citrate synthase cit 0.0064
4580 Citrate synthase gltA 0.0064
5599 3-carboxy-cis,cis-muconate cycloisomerase pcaB 0.0064
5328 Prostaglandin F synthase Tb11.02.2310 0.0064
4992 Cytochrome c peroxidase Not Available 0.0064
2555 Pol polyprotein pol 0.0064
3242 Pol polyprotein gag-pol 0.0064
3471 Pol polyprotein gag-pro-pol 0.0064
5256 Pol polyprotein pol 0.0064
6469 Pol polyprotein gag-pol 0.0064
6565 Pol polyprotein Not Available 0.0064
3583 6-phosphogluconolactonase pgl 0.0059
2149 Angiogenin ANG 0.0059
2603 Beta-lactamase II blm 0.0059
1467 Tumor necrosis factor ligand superfamily member 13B TNFSF13B 0.0059
2521 Cell division protein ftsZ ftsZ 0.0059
3301 Cell division protein ftsZ ftsZ 0.0059
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0059
2869 1-deoxy-D-xylulose 5-phosphate reductoisomerase dxr 0.0056
2286 Isocitrate dehydrogenase [NADP] icd 0.0056
2302 Isocitrate dehydrogenase [NADP] icd 0.0056
2771 Isocitrate dehydrogenase [NADP] icd 0.0056
3486 Fumarate hydratase class II fumC 0.0056
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0056
2942 Sialidase nanH 0.0056
3546 Sialidase nedA 0.0056
857 Malate dehydrogenase, mitochondrial MDH2 0.0053
941 Betaine--homocysteine S-methyltransferase 1 BHMT 0.0052
2697 Uridine-cytidine kinase 2 UCK2 0.0051
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0051
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0051
332 Beta-lactamase blaZ 0.0051
2478 Beta-lactamase ampC 0.0051
2613 Beta-lactamase ampC 0.0051
2635 Beta-lactamase ampC 0.0051
2700 Beta-lactamase penP 0.0051
5445 Beta-lactamase blaB 0.0051
6019 Beta-lactamase SHV-7 0.0051
6701 Beta-lactamase cphA 0.0051
1123 Eosinophil cationic protein RNASE3 0.0051
2452 Tryptophanyl-tRNA synthetase trpS 0.005
5579 Carboxypeptidase B CPB1 0.0048
3478 Glucose-1-phosphate thymidylyltransferase rmlA 0.0047
4277 Glucose-1-phosphate thymidylyltransferase rmlA 0.0047
3384 Macrophage migration inhibitory factor MIF 0.0047
411 Glycine N-methyltransferase GNMT 0.0046
128 Adenine phosphoribosyltransferase APRT 0.0042
822 Aldose reductase AKR1B1 0.0036
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0036
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0034
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0027
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