DT-Web

DB03970 - (6,7-Dihydro-5h-Cyclopenta[D]Imidazo[2,1-B]Thiazol-2-Yl]-4,7-Dihydro[1,4]Thiazepine-3,6-Dicarboxylic Acid


Identification
Name (6,7-Dihydro-5h-Cyclopenta[D]Imidazo[2,1-B]Thiazol-2-Yl]-4,7-Dihydro[1,4]Thiazepine-3,6-Dicarboxylic Acid
Accession Number DB03970 (EXPT03247)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 363.411
Groups experimental
Monoisotopic Weight 363.034747299
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Beta-lactamase
Name Beta-lactamase
Gene Name ampC
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 2.1556
Beta-lactamase SHV-1 precursor
Name Beta-lactamase SHV-1 precursor
Gene Name bla
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.9156
Beta-lactamase SHV-1
Name Beta-lactamase SHV-1
Gene Name bla
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.7869
Class C beta-lactamase
Name Class C beta-lactamase
Gene Name Not Available
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.9345

Predictions


Id Partner name Gene Name Score
332 Beta-lactamase blaZ 2.1556
2478 Beta-lactamase ampC 2.1556
2635 Beta-lactamase ampC 2.1556
2700 Beta-lactamase penP 2.1556
5445 Beta-lactamase blaB 2.1556
6019 Beta-lactamase SHV-7 2.1556
6701 Beta-lactamase cphA 2.1556
3701 Beta-lactamase SHV-2 precursor bla 0.2002
6643 Beta-lactamase AmpC ampC 0.1401
2858 Beta-lactamase TEM bla 0.1165
6396 Beta-lactamase TEM bla 0.1165
2340 Beta-lactamase PSE-2 bla 0.0828
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