DT-Web

DB03932 - LFA703


Identification
Name LFA703
Accession Number DB03932 (EXPT00387)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 603.7881
Groups experimental
Monoisotopic Weight 603.355988305
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Integrin alpha-L
Name Integrin alpha-L
Gene Name ITGAL
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.2506

Predictions


Id Partner name Gene Name Score
660 T-cell surface glycoprotein CD1a CD1A 0.0358
6063 Major histocompatibility complex class I-related gene protein MR1 0.0358
6066 Integrin alpha-V ITGAV 0.0358
5955 T-cell surface glycoprotein CD4 CD4 0.0358
6065 Integrin beta-1 ITGB1 0.0358
3820 Low affinity immunoglobulin gamma Fc region receptor II-b FCGR2B 0.0358
942 T-lymphocyte activation antigen CD86 CD86 0.0288
2039 Integrin beta-3 ITGB3 0.0253
3817 Complement C1q subcomponent subunit C C1QC 0.0165
3816 Complement C1q subcomponent subunit B C1QB 0.0165
3815 Complement C1q subcomponent subunit A C1QA 0.0164
1102 Low affinity immunoglobulin gamma Fc region receptor III-B FCGR3B 0.0163
3818 Low affinity immunoglobulin gamma Fc region receptor III-A FCGR3A 0.0163
3819 Low affinity immunoglobulin gamma Fc region receptor II-a FCGR2A 0.0163
3821 Low affinity immunoglobulin gamma Fc region receptor II-c FCGR2C 0.0163
3814 Complement C1r subcomponent C1R 0.0163
784 High affinity immunoglobulin gamma Fc receptor I FCGR1A 0.0155
6044 Serum paraoxonase/lactonase 3 PON3 0.0114
4122 Histone deacetylase 2 HDAC2 0.0099
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0087
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0087
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0074
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0069
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0067
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0061
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.006
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0057
6107 Cytochrome P450 3A7 CYP3A7 0.0051
4118 Cytochrome P450 3A5 CYP3A5 0.0048
4924 Cytochrome P450 2C8 CYP2C8 0.0048
6016 Cytochrome P450 2C19 CYP2C19 0.0046
1588 Multidrug resistance protein 1 ABCB1 0.0044
4757 Cytochrome P450 2C9 CYP2C9 0.0044
4119 Cytochrome P450 2D6 CYP2D6 0.0043
4512 Cytochrome P450 3A4 CYP3A4 0.0039
↑