DT-Web

DB03847 - Gamma-Carboxy-Glutamic Acid


Identification
Name Gamma-Carboxy-Glutamic Acid
Accession Number DB03847 (EXPT00902)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 191.1388
Groups experimental
Monoisotopic Weight 191.042987025
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Prothrombin
Name Prothrombin
Gene Name F2
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.8594
Osteocalcin
Name Osteocalcin
Gene Name BGLAP
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.6696
Coagulation factor X
Name Coagulation factor X
Gene Name F10
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.7316
Coagulation factor IX
Name Coagulation factor IX
Gene Name F9
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.0336

Predictions


Id Partner name Gene Name Score
448 Vitamin K-dependent gamma-carboxylase GGCX 0.1975
3176 Trypsin-1 PRSS1 0.1044
5142 Protein-tyrosine-phosphatase PPI 0.0747
6315 V-type proton ATPase subunit B, brain isoform ATP6V1B2 0.0665
1654 Interleukin-1 beta IL1B 0.061
4218 Ribonucleoside-diphosphate reductase M2 subunit RRM2 0.0568
566 Serotransferrin TF 0.0535
309 Antithrombin-III SERPINC1 0.0533
369 Coagulation factor VII F7 0.0504
1074 Urokinase-type plasminogen activator PLAU 0.0362
400 Coagulation factor IX F9 0.0336
422 Vitamin K-dependent protein C PROC 0.028
4081 Vitamin K epoxide reductase complex subunit 1-like protein 1 VKORC1L1 0.0251
604 Vitamin K-dependent protein Z PROZ 0.0251
1245 Vitamin K-dependent protein S PROS1 0.0239
3831 Low-density lipoprotein receptor-related protein 1 LRP1 0.0235
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0202
1757 Myeloperoxidase MPO 0.0201
19 Coagulation factor VIII F8 0.0196
3851 Serine protease hepsin HPN 0.0171
3119 Fimbrial protein pilE1 0.0168
1719 Heparanase HPSE 0.0164
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0158
2058 P-selectin SELP 0.0156
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0152
6182 Cytochrome P450 2J2 CYP2J2 0.0145
3917 Methylenetetrahydrofolate reductase MTHFR 0.0144
6020 Aldehyde oxidase AOX1 0.0134
1334 Tissue factor pathway inhibitor TFPI 0.0132
3947 Xanthine dehydrogenase/oxidase XDH 0.0126
6564 Prephenate dehydrogenase tyrA 0.0122
6240 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1 0.0122
1547 Coagulation factor XI F11 0.0119
2139 Tissue factor F3 0.0111
3842 Multiple coagulation factor deficiency protein 2 MCFD2 0.0103
3841 ERGIC-53 protein LMAN1 0.0102
3840 Asialoglycoprotein receptor 2 ASGR2 0.0102
1847 78 kDa glucose-regulated protein HSPA5 0.0102
1635 von Willebrand factor VWF 0.0102
4118 Cytochrome P450 3A5 CYP3A5 0.0102
2331 HTH-type transcriptional regulator qacR qacR 0.01
6461 HTH-type transcriptional regulator qacR qacR 0.01
5718 Cytochrome P450 2A6 CYP2A6 0.0097
4200 Cytochrome P450 1A2 CYP1A2 0.0097
6828 TetR family transcriptional repressor LfrR lfrR 0.0095
256 Tyrosyl-tRNA synthetase, cytoplasmic YARS 0.0093
6024 Cytochrome P450 1A1 CYP1A1 0.0091
3384 Macrophage migration inhibitory factor MIF 0.009
1516 Calnexin CANX 0.0089
6013 Cytochrome P450 2E1 CYP2E1 0.0087
4512 Cytochrome P450 3A4 CYP3A4 0.0083
1588 Multidrug resistance protein 1 ABCB1 0.0079
3830 Calreticulin CALR 0.0073
3839 Phytanoyl-CoA dioxygenase, peroxisomal PHYH 0.0072
4757 Cytochrome P450 2C9 CYP2C9 0.0068
4165 P2Y purinoceptor 2 P2RY2 0.0047
2654 Complement control protein C3L 0.0037
1959 Platelet factor 4 PF4 0.0035
3865 Serpin B6 SERPINB6 0.0035
1986 Ceruloplasmin CP 0.0035
430 Follicle-stimulating hormone receptor FSHR 0.0034
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0034
5455 Arylsulfatase A ARSA 0.0032
3833 Plasma serine protease inhibitor SERPINA5 0.0031
4604 Liver carboxylesterase 1 CES1 0.0031
2072 Endothelial protein C receptor PROCR 0.0031
46 Coagulation factor V F5 0.0031
814 Ryanodine receptor 1 RYR1 0.0029
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0027
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0027
2981 Phospholipase A2, membrane associated PLA2G2A 0.0026
2021 Thrombomodulin THBD 0.0026
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0025
267 Plasminogen activator inhibitor 1 SERPINE1 0.0023
723 Cytosolic phospholipase A2 PLA2G4A 0.0023
4924 Cytochrome P450 2C8 CYP2C8 0.0022
6016 Cytochrome P450 2C19 CYP2C19 0.0021
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