DT-Web

DB03183 - 1-(4-Aminophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester


Identification
Name 1-(4-Aminophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester
Accession Number DB03183 (EXPT00243)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 259.3037
Groups experimental
Monoisotopic Weight 259.132076803
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Name cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Gene Name PDE4D
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available

Predictions


Id Partner name Gene Name Score
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.2616
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.131
4109 cAMP-specific 3',5'-cyclic phosphodiesterase 4C PDE4C 0.0863
779 High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A PDE7A 0.0311
6216 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A PDE8A 0.023
691 cAMP-specific 3',5'-cyclic phosphodiesterase 7B PDE7B 0.0191
5360 High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A PDE9A 0.0149
3806 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A 0.0138
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0132
2256 cGMP-inhibited 3',5'-cyclic phosphodiesterase B PDE3B 0.0122
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.011
6217 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B PDE8B 0.0097
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0088
1178 Adenosine A2a receptor ADORA2A 0.0084
1792 Tissue-type plasminogen activator PLAT 0.0082
16 Adenosine A1 receptor ADORA1 0.008
527 Prostacyclin receptor PTGIR 0.0071
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0067
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0067
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0065
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0064
851 5'-AMP-activated protein kinase subunit beta-2 PRKAB2 0.0056
388 AMP deaminase 1 AMPD1 0.0056
2684 Histidine triad nucleotide-binding protein 1 HINT1 0.0055
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0054
4198 Fructose-1,6-bisphosphatase 1 FBP1 0.005
1291 cAMP response element-binding protein CREB1 0.0049
704 Long-chain-fatty-acid--CoA ligase 1 ACSL1 0.0049
821 Acetyl-coenzyme A synthetase 2-like, mitochondrial ACSS1 0.0049
386 Acetyl-coenzyme A synthetase, cytoplasmic ACSS2 0.0049
297 Adenylate cyclase type 1 ADCY1 0.0049
128 Adenine phosphoribosyltransferase APRT 0.0047
281 5'-AMP-activated protein kinase subunit beta-1 PRKAB1 0.0047
10 Glycogen phosphorylase, liver form PYGL 0.0046
748 5'-AMP-activated protein kinase catalytic subunit alpha-1 PRKAA1 0.0045
6021 Adenosine kinase ADK 0.0045
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0043
492 Histamine H1 receptor HRH1 0.0043
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