DT-Web

DB03115 - 5-Bromo-N-(2,3-Dihydroxypropoxy)-3,4-Difluoro-2-[(2-Fluoro-4-Iodophenyl)Amino]Benzamide


Identification
Name 5-Bromo-N-(2,3-Dihydroxypropoxy)-3,4-Difluoro-2-[(2-Fluoro-4-Iodophenyl)Amino]Benzamide
Accession Number DB03115 (EXPT00634)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 561.089
Groups experimental
Monoisotopic Weight 559.905547596
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Dual specificity mitogen-activated protein kinase kinase 1
Name Dual specificity mitogen-activated protein kinase kinase 1
Gene Name MAP2K1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.5432

Predictions


Id Partner name Gene Name Score
1144 Hepatocyte growth factor receptor MET 0.0926
6893 Calcium/calmodulin-dependent protein kinase type II gamma chain CAMK2G 0.0284
6824 Tyrosine-protein kinase Lyn LYN 0.0262
4512 Cytochrome P450 3A4 CYP3A4 0.0257
2599 Tyrosine-protein kinase HCK HCK 0.0247
4924 Cytochrome P450 2C8 CYP2C8 0.0237
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0177
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0152
2240 Cell division protein kinase 2 CDK2 0.0122
1588 Multidrug resistance protein 1 ABCB1 0.0074
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