DT-Web

DB03046 - 7-Methoxy-8-[1-(Methylsulfonyl)-1h-Pyrazol-4-Yl]Naphthalene-2-Carboximidamide


Identification
Name 7-Methoxy-8-[1-(Methylsulfonyl)-1h-Pyrazol-4-Yl]Naphthalene-2-Carboximidamide
Accession Number DB03046 (EXPT03180)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 344.388
Groups experimental
Monoisotopic Weight 344.094311088
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Urokinase-type plasminogen activator
Name Urokinase-type plasminogen activator
Gene Name PLAU
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.5199

Predictions


Id Partner name Gene Name Score
3176 Trypsin-1 PRSS1 0.1172
54 Prothrombin F2 0.0708
3011 Suppressor of tumorigenicity protein 14 ST14 0.019
3851 Serine protease hepsin HPN 0.0175
2889 Kallikrein-6 KLK6 0.0115
2947 Trypsin sprT 0.0114
3834 Nidogen-1 NID1 0.0104
3211 3,2-trans-enoyl-CoA isomerase, mitochondrial DCI 0.0099
4814 Copper transport protein ATOX1 ATOX1 0.0099
3833 Plasma serine protease inhibitor SERPINA5 0.009
1349 Plasminogen activator inhibitor 2 SERPINB2 0.009
2886 Trypsin-3 PRSS3 0.0075
791 Urokinase plasminogen activator surface receptor PLAUR 0.0075
1244 Low-density lipoprotein receptor-related protein 2 LRP2 0.0071
267 Plasminogen activator inhibitor 1 SERPINE1 0.0067
387 Amiloride-sensitive amine oxidase [copper-containing] ABP1 0.0062
7187 Amiloride-sensitive amine oxidase [copper-containing] ABP1 0.0062
827 Sodium/hydrogen exchanger 1 SLC9A1 0.0062
234 Plasminogen PLG 0.006
2236 Casein kinase II subunit alpha CSNK2A1 0.006
1792 Tissue-type plasminogen activator PLAT 0.006
749 Amiloride-sensitive cation channel 1, neuronal ACCN1 0.0056
550 Amiloride-sensitive sodium channel subunit delta SCNN1D 0.005
27 Amiloride-sensitive sodium channel subunit beta SCNN1B 0.005
552 Amiloride-sensitive sodium channel subunit gamma SCNN1G 0.005
213 Amiloride-sensitive sodium channel subunit alpha SCNN1A 0.005
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0049
833 Organic cation/carnitine transporter 1 SLC22A4 0.0031
6144 Solute carrier family 22 member 2 SLC22A2 0.0026
6145 Solute carrier family 22 member 1 SLC22A1 0.0026
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