DT-Web

DB03015 - 6-Hydroxy-1,6-Dihydro Purine Nucleoside


Identification
Name 6-Hydroxy-1,6-Dihydro Purine Nucleoside
Accession Number DB03015 (EXPT02660)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 271.2499
Groups experimental
Monoisotopic Weight 271.10424461
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Adenosine deaminase
Name Adenosine deaminase
Gene Name ADA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.3175

Predictions


Id Partner name Gene Name Score
338 DNA polymerase UL30 0.0376
379 DNA polymerase UL54 0.0376
697 DNA polymerase ORF28 0.0376
2482 DNA polymerase 43 0.0376
4104 DNA polymerase BALF5 0.0376
509 Thymidine kinase TK 0.0282
570 Thymidine kinase TK 0.0282
2559 Thymidine kinase TK 0.0282
3430 Thymidine kinase tdk 0.0282
3518 Thymidine kinase TK 0.0282
5301 Thymidine kinase tdk 0.0282
5771 Thymidine kinase ORF36 0.0282
7009 Thymidine kinase ORF36 0.0282
6083 Deoxyguanosine kinase, mitochondrial DGUOK 0.0278
603 DNA polymerase alpha catalytic subunit POLA1 0.0209
6044 Serum paraoxonase/lactonase 3 PON3 0.0199
268 Adenosine A2b receptor ADORA2B 0.0175
4773 Deoxycytidine kinase DCK 0.0165
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0137
1178 Adenosine A2a receptor ADORA2A 0.0137
16 Adenosine A1 receptor ADORA1 0.0131
390 Adenosine A3 receptor ADORA3 0.013
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0128
3811 Cytochrome P450 19A1 CYP19A1 0.0119
6021 Adenosine kinase ADK 0.0117
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.0113
6171 Solute carrier family 28 member 3 SLC28A3 0.0107
4200 Cytochrome P450 1A2 CYP1A2 0.0101
6136 Multidrug resistance-associated protein 5 ABCC5 0.0081
2164 Multidrug resistance-associated protein 4 ABCC4 0.0068
1588 Multidrug resistance protein 1 ABCB1 0.0046
4122 Histone deacetylase 2 HDAC2 0.0042
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0036
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0033
1898 Cytochrome P450 1B1 CYP1B1 0.0027
6143 Solute carrier family 22 member 7 SLC22A7 0.0026
6024 Cytochrome P450 1A1 CYP1A1 0.0022
6013 Cytochrome P450 2E1 CYP2E1 0.0021
4924 Cytochrome P450 2C8 CYP2C8 0.0019
4757 Cytochrome P450 2C9 CYP2C9 0.0018
4119 Cytochrome P450 2D6 CYP2D6 0.0017
4512 Cytochrome P450 3A4 CYP3A4 0.0016
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