DT-Web

DB02812 - (2s,4r)-1-Acetyl-N-[(1s)-4-[(Aminoiminomethyl)Amino]-1-(2-Benzothiazolylcarbonyl)Butyl]-4-Hydroxy-2-Pyrrolidinecarboxamide


Identification
Name (2s,4r)-1-Acetyl-N-[(1s)-4-[(Aminoiminomethyl)Amino]-1-(2-Benzothiazolylcarbonyl)Butyl]-4-Hydroxy-2-Pyrrolidinecarboxamide
Accession Number DB02812 (EXPT00391)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 446.523
Groups experimental
Monoisotopic Weight 446.17362404
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Trypsin-1
Name Trypsin-1
Gene Name PRSS1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.6672

Predictions


Id Partner name Gene Name Score
54 Prothrombin F2 0.1044
1074 Urokinase-type plasminogen activator PLAU 0.0599
3851 Serine protease hepsin HPN 0.0215
6011 Chymotrypsinogen B CTRB1 0.018
2324 Botulinum neurotoxin type B botB 0.017
2686 Tryptase beta-2 TPSB2 0.0162
520 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA 0.0148
2306 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA 0.0148
2367 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA 0.0148
2255 Copper amine oxidase tynA 0.0129
2914 Triosephosphate isomerase, glycosomal Not Available 0.0123
1812 Kallikrein-1 KLK1 0.0107
2517 Subtilisin BPN' apr 0.0103
3382 Glycolipid transfer protein GLTP 0.0099
2331 HTH-type transcriptional regulator qacR qacR 0.0076
6461 HTH-type transcriptional regulator qacR qacR 0.0076
387 Amiloride-sensitive amine oxidase [copper-containing] ABP1 0.0075
7187 Amiloride-sensitive amine oxidase [copper-containing] ABP1 0.0075
1119 Peroxiredoxin-5, mitochondrial PRDX5 0.0074
6882 Iodotyrosine dehalogenase 1 IYD 0.0071
6881 Nickel-binding periplasmic protein nikA 0.0071
6880 Alpha-amylase G-6 BH0413 0.0071
234 Plasminogen PLG 0.0062
474 Acetylcholinesterase ACHE 0.0056
2889 Kallikrein-6 KLK6 0.0047
2947 Trypsin sprT 0.0047
3011 Suppressor of tumorigenicity protein 14 ST14 0.0041
4814 Copper transport protein ATOX1 ATOX1 0.0041
3211 3,2-trans-enoyl-CoA isomerase, mitochondrial DCI 0.0041
6264 cAMP-dependent protein kinase inhibitor alpha PKIA 0.0036
2886 Trypsin-3 PRSS3 0.0034
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0033
2236 Casein kinase II subunit alpha CSNK2A1 0.0025
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