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DB02567 - PD173955


Identification
Name PD173955
Accession Number DB02567 (EXPT02468)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 443.349
Groups experimental
Monoisotopic Weight 442.042187258
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Tyrosine-protein kinase transforming protein Abl
Name Tyrosine-protein kinase transforming protein Abl
Gene Name ABL
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.0185

Predictions


Id Partner name Gene Name Score
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.2091
5449 Hypothetical gliding protein mglB 0.0196
4705 Manganese catalase Not Available 0.0196
5443 UPF0189 protein ymdB ymdB 0.0196
5446 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase HI_1679 0.0196
3781 Thiol:disulfide interchange protein dsbC precursor dsbC 0.0196
5439 33 kDa chaperonin hslO 0.0196
332 Beta-lactamase blaZ 0.0196
2478 Beta-lactamase ampC 0.0196
2613 Beta-lactamase ampC 0.0196
2635 Beta-lactamase ampC 0.0196
2700 Beta-lactamase penP 0.0196
5445 Beta-lactamase blaB 0.0196
6019 Beta-lactamase SHV-7 0.0196
6701 Beta-lactamase cphA 0.0196
5448 Ribonuclease Z rnz 0.0196
5440 UPF0067 protein yebR yebR 0.0196
2720 Copper-containing nitrite reductase nirK 0.0196
5454 Internalin-A inlA 0.0196
5447 Lethal(3)malignant brain tumor-like protein L3MBTL1 0.0196
2714 Chorismate mutase aroH 0.0171
4611 Chorismate mutase aroG 0.0171
4498 Ornithine cyclodeaminase PP3533 0.0171
4771 Dissimilatory copper-containing nitrite reductase nir 0.0171
3356 Diaminopimelate decarboxylase lysA 0.0171
5450 Prolyl endopeptidase Pep pep 0.0171
3274 Hydroxylamine reductase hcp 0.0171
4804 Hydroxylamine reductase hcp 0.0171
3399 Limonene-1,2-epoxide hydrolase limA 0.0158
3697 Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase glmU 0.0158
3736 Glyceraldehyde-3-phosphate dehydrogenase A gapA 0.0158
5180 L(+)-mandelate dehydrogenase mdlB 0.0149
3500 Putative family 31 glucosidase yicI yicI 0.0149
1615 Chymase CMA1 0.0142
4608 Putative cytochrome P450 SCO1207 0.0142
4963 Putative cytochrome P450 SCO2884 0.0142
6254 Putative cytochrome P450 SCO6998 0.0142
2597 Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] glmS 0.0137
597 Dihydropteridine reductase QDPR 0.0137
3480 Mannan endo-1,4-beta-mannosidase manA 0.0137
577 Argininosuccinate lyase ASL 0.0136
365 Dihydrofolate reductase DHFR 0.0133
2381 Dihydrofolate reductase DFR1 0.0133
2833 Dihydrofolate reductase Not Available 0.0133
2931 Dihydrofolate reductase folA 0.0133
3544 Dihydrofolate reductase folA 0.0133
3682 Dihydrofolate reductase folA 0.0133
6642 Dihydrofolate reductase folA 0.0133
6756 Dihydrofolate reductase dfrA 0.0133
287 Beta-1,4-galactosyltransferase 1 B4GALT1 0.0128
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0105
904 Glutathione S-transferase P GSTP1 0.0089
474 Acetylcholinesterase ACHE 0.0077
3923 Cholinesterase BCHE 0.0062
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