DB02465 - Methoxy arachidonyl fluorophosphonate
| Identification | |
|---|---|
| Name | Methoxy arachidonyl fluorophosphonate |
| Accession Number | DB02465 (EXPT02119) |
| Type | small molecule |
| Description | Methoxy arachidonyl fluorophosphonate, commonly referred as MAFP, is an irreversible active site-directed enzyme inhibitor that inhibits nearly all serine hydrolases and serine proteases. It inhibits phospholipase A2 and fatty acid amide hydrolase with special potency, displaying IC50 values in the low-nanomolar range. |
| Structure |
|
| Categories (*) | |
| Molecular Weight | 370.4815 |
| Groups | experimental |
| Monoisotopic Weight | 370.243695113 |
| Pharmacology | |
| Indication | Not Available |
| Mechanism of action | Not Available |
| Absorption | Not Available |
| Protein binding | Not Available |
| Biotransformation | Not Available |
| Route of elimination | Not Available |
| Toxicity | Not Available |
| Affected organisms | Not Available |
| Interactions | |
| Drug Interactions | Not Available |
| Food Interactions | Not Available |
Targets
| Fatty-acid amide hydrolase | |
|---|---|
| Name | Fatty-acid amide hydrolase |
| Gene Name | FAAH |
| Pharmacological action | unknown |
| Actions | Not Available |
| References |
|
| DTHybrid score | 1.0136 |