DT-Web

DB02272 - Porphobilinogen


Identification
Name Porphobilinogen
Accession Number DB02272 (EXPT02507)
Type small molecule
Description Porphobilinogen is a pyrrole involved in porphyrin metabolism. It is generated by the enzyme ALA dehydratase, and converted into hydroxymethyl bilane by the enzyme porphobilinogen deaminase.
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 225.2212
Groups experimental
Monoisotopic Weight 225.087531914
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Delta-aminolevulinic acid dehydratase
Name Delta-aminolevulinic acid dehydratase
Gene Name ALAD
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.353

Predictions


Id Partner name Gene Name Score
2356 Delta-aminolevulinic acid dehydratase hemB 1.353
3613 Delta-aminolevulinic acid dehydratase hemB 1.353
3674 Delta-aminolevulinic acid dehydratase hemB 1.353
383 Glycine amidinotransferase, mitochondrial GATM 0.0998
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.033
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0319
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