DT-Web

DB02062 - N-[3-[(1-Aminoethyl)(Hydroxy)Phosphoryl]-2-(1,1'-Biphenyl-4-Ylmethyl)Propanoyl]Alanine


Identification
Name N-[3-[(1-Aminoethyl)(Hydroxy)Phosphoryl]-2-(1,1'-Biphenyl-4-Ylmethyl)Propanoyl]Alanine
Accession Number DB02062 (EXPT00710)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 418.4232
Groups experimental
Monoisotopic Weight 418.165758496
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Neprilysin
Name Neprilysin
Gene Name MME
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.3849
Leukotriene A-4 hydrolase
Name Leukotriene A-4 hydrolase
Gene Name LTA4H
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.8363

Predictions


Id Partner name Gene Name Score
957 Glucagon-like peptide 1 receptor GLP1R 0.0863
2757 Inorganic pyrophosphatase ppa 0.0734
6238 Inorganic pyrophosphatase ppa 0.0734
6968 Inorganic pyrophosphatase PPA1 0.0734
244 Angiotensin-converting enzyme ACE 0.0679
6285 Thermolysin npr 0.0648
2457 Bacillolysin nprS 0.0635
952 Dipeptidyl peptidase 4 DPP4 0.0461
1540 Mitogen-activated protein kinase 14 MAPK14 0.0386
2544 Bacterial leucyl aminopeptidase Not Available 0.0319
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0131
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0127
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