DT-Web

DB01796 - Quinolinic Acid


Identification
Name Quinolinic Acid
Accession Number DB01796 (EXPT02391)
Type small molecule
Description A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS. [PubChem]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 167.1189
Groups experimental
Monoisotopic Weight 167.021857653
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Nicotinate-nucleotide pyrophosphorylase [carboxylating]
Name Nicotinate-nucleotide pyrophosphorylase [carboxylating]
Gene Name nadC
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.9008
Nicotinate-nucleotide pyrophosphorylase [carboxylating]
Name Nicotinate-nucleotide pyrophosphorylase [carboxylating]
Gene Name nadC
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.9008

Predictions


Id Partner name Gene Name Score
583 Nicotinate-nucleotide pyrophosphorylase [carboxylating] QPRT 1.9008
2264 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase cobT 0.1465
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.1052
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