DT-Web

DB01705 - Bis(5-Amidino-Benzimidazolyl)Methane


Identification
Name Bis(5-Amidino-Benzimidazolyl)Methane
Accession Number DB01705 (EXPT00620)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 332.3625
Groups experimental
Monoisotopic Weight 332.149792552
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Trypsin-1
Name Trypsin-1
Gene Name PRSS1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.8076
Botulinum neurotoxin type B
Name Botulinum neurotoxin type B
Gene Name botB
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.4028

Predictions


Id Partner name Gene Name Score
54 Prothrombin F2 0.1044
1074 Urokinase-type plasminogen activator PLAU 0.0599
5416 Coat protein VP1 Not Available 0.0484
5414 Fiber protein L5 0.0471
5418 Fiber protein L5 0.0471
1756 E-selectin SELE 0.0471
3547 Enterotoxin type B entB 0.0447
1130 Lithostathine 1 alpha REG1A 0.041
4857 Zinc-alpha-2-glycoprotein AZGP1 0.041
3629 Endo-N-acetylneuraminidase Not Available 0.041
2570 Tetanus toxin tetX 0.0389
3140 Hemagglutinin-neuraminidase HN 0.0357
3609 Hemagglutinin-neuraminidase HN 0.0357
2723 Cholera enterotoxin subunit B ctxB 0.0328
2058 P-selectin SELP 0.0323
64 Neuraminidase NA 0.0287
641 Neuraminidase NA 0.0287
2676 Neuraminidase NA 0.0287
3026 Neuraminidase NA 0.0287
3519 Neuraminidase NA 0.0287
6007 Neuraminidase NA 0.0287
3851 Serine protease hepsin HPN 0.0215
4604 Liver carboxylesterase 1 CES1 0.0202
6011 Chymotrypsinogen B CTRB1 0.018
2686 Tryptase beta-2 TPSB2 0.0162
520 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA 0.0148
2306 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA 0.0148
2367 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA 0.0148
2255 Copper amine oxidase tynA 0.0129
2914 Triosephosphate isomerase, glycosomal Not Available 0.0123
1812 Kallikrein-1 KLK1 0.0107
2517 Subtilisin BPN' apr 0.0103
3382 Glycolipid transfer protein GLTP 0.0099
3689 Endoglucanase A celA 0.0085
5411 Slt-IIvB stxB2e 0.0085
3009 Beta-glucanase Not Available 0.0085
5046 Ecotin eco 0.0085
5554 D-galactose-binding periplasmic protein mglB 0.0085
3741 D-galactose-binding periplasmic protein precursor mglB 0.0085
5563 Galectin-2 LGALS2 0.0085
5565 Inorganic polyphosphate/ATP-glucomannokinase ppgmk 0.0085
4670 Cellulase B celB 0.0085
5562 Hexokinase Not Available 0.0085
5568 Endoglucanase C307 celC307 0.0085
3793 Aspartate ammonia-lyase aspA 0.0085
4668 Laminarinase TM_0024 0.0085
1875 Pulmonary surfactant-associated protein D SFTPD 0.0085
5569 Endo-1,4-beta glucanase EngF engF 0.0085
5553 Endoglucanase E1 Acel_0614 0.0085
5559 Neopullulanase nplT 0.0085
4671 Endoglucanase C cenC 0.0085
3744 Endoglucanase SS precursor celS 0.0085
5570 Endoglucanase E-4 celD 0.0085
4667 BH0236 protein BH0236 0.0085
2331 HTH-type transcriptional regulator qacR qacR 0.0076
6461 HTH-type transcriptional regulator qacR qacR 0.0076
387 Amiloride-sensitive amine oxidase [copper-containing] ABP1 0.0075
7187 Amiloride-sensitive amine oxidase [copper-containing] ABP1 0.0075
1184 Interferon beta IFNB1 0.0074
3525 ADP-ribose pyrophosphatase, mitochondrial NUDT9 0.0074
1503 Galectin-7 LGALS7 0.0074
4509 Acetoin(diacetyl) reductase budC 0.0074
5247 Endo-1,4-beta-xylanase Not Available 0.0074
5248 Endo-1,4-beta-xylanase xlnA 0.0074
5250 Endo-1,4-beta-xylanase xyl 0.0074
5056 Maltooligosyltrehalose trehalohydrolase, putative treZ 0.0074
5176 YtnJ moxC 0.0074
5498 Maltoporin lamB 0.0074
5561 Maltoporin lamB 0.0074
4622 Amylase Not Available 0.0074
2728 Glucan 1,4-alpha-maltotetraohydrolase amyP 0.0074
4669 Endo-1,4-beta-xylanase A xynA 0.0074
4715 Endo-1,4-beta-xylanase A xlnA 0.0074
5560 Endo-1,4-beta-xylanase A xynA 0.0074
2705 Dimethyl sulfoxide reductase dmsA 0.0074
1119 Peroxiredoxin-5, mitochondrial PRDX5 0.0074
6882 Iodotyrosine dehalogenase 1 IYD 0.0071
6881 Nickel-binding periplasmic protein nikA 0.0071
6880 Alpha-amylase G-6 BH0413 0.0071
2856 Glucosamine-6-phosphate isomerase GNPDA1 0.0068
3153 Quinoprotein glucose dehydrogenase-B gdhB 0.0068
3747 Cellulase B precursor celB 0.0068
4811 Amylosucrase ams 0.0068
2531 Alpha-amylase amyE 0.0068
2948 Alpha-amylase amy 0.0068
3169 Alpha-amylase Not Available 0.0068
4819 Hydrolase Not Available 0.0068
5249 Hydrolase Not Available 0.0068
5436 Hydrolase Not Available 0.0068
3091 Maltodextrin phosphorylase malP 0.0068
2541 Neopullulanase 1 tvaI 0.0068
2564 Glucan 1,4-alpha-maltohexaosidase Not Available 0.0068
2606 Neopullulanase 2 tvaII 0.0068
3225 Shiga toxin B-chain stxB 0.0065
4666 Fucose-binding lectin PA-IIL lecB 0.0065
4830 Aldose 1-epimerase galM 0.0065
2826 Glucose--fructose oxidoreductase gfo 0.0065
3365 Beta-amylase spoII 0.0065
1881 Hexokinase-1 HK1 0.0065
2372 Bifunctional tail protein 9 0.0065
234 Plasminogen PLG 0.0062
3030 Salivary alpha-amylase AMY1A 0.0062
6614 Lactase-like protein LCTL 0.0062
2293 Cyclomaltodextrin glucanotransferase Not Available 0.0062
2508 Cyclomaltodextrin glucanotransferase cgt 0.0062
2523 Cyclomaltodextrin glucanotransferase cgt 0.0062
3207 Cyclomaltodextrin glucanotransferase amyA 0.0062
1675 Glucokinase GCK 0.0062
4662 Glucokinase glk 0.0062
3668 Maltose-binding periplasmic protein precursor malE 0.0059
2802 Endoglucanase G celCCG 0.0059
2448 Exoglucanase/xylanase [Includes: Exoglucanase cex 0.0059
4692 A/G-specific adenine glycosylase mutY 0.0059
4272 POSSIBLE CELLULASE CELA1 celA1 0.0058
474 Acetylcholinesterase ACHE 0.0056
2440 Endoglucanase F celCCF 0.0056
2430 Chondroitinase B cslB 0.0055
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0054
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0054
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0054
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0054
2245 Xylose isomerase xylA 0.0052
2253 Xylose isomerase xylA 0.0052
2260 Xylose isomerase xylA 0.0052
2431 Xylose isomerase xylA 0.0052
2252 Endoglucanase 5A cel5A 0.0051
10 Glycogen phosphorylase, liver form PYGL 0.0048
2427 Ferrichrome-iron receptor fhuA 0.0048
2889 Kallikrein-6 KLK6 0.0047
4513 Pancreatic alpha-amylase AMY2A 0.0047
2947 Trypsin sprT 0.0047
3011 Suppressor of tumorigenicity protein 14 ST14 0.0041
4814 Copper transport protein ATOX1 ATOX1 0.0041
3211 3,2-trans-enoyl-CoA isomerase, mitochondrial DCI 0.0041
1152 Glycogen phosphorylase, muscle form PYGM 0.0039
6264 cAMP-dependent protein kinase inhibitor alpha PKIA 0.0036
2886 Trypsin-3 PRSS3 0.0034
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0033
2236 Casein kinase II subunit alpha CSNK2A1 0.0025
20 Prostaglandin G/H synthase 1 PTGS1 0.0024
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