DB01481 - Delta1-dihydrotestosterone
| Identification | |
|---|---|
| Name | Delta1-dihydrotestosterone |
| Accession Number | DB01481 |
| Type | small molecule |
| Description | Delta1-dihydrotestosterone is an anabolic steroid that differs from testosterone by having a 1,2-double bond instead of 4,5-double bond in its A ring. [Wikipedia] |
| Structure |
|
| Categories (*) | |
| Molecular Weight | 288.4244 |
| Groups | illicit |
| Monoisotopic Weight | 288.20893014 |
| Pharmacology | |
| Indication | Not Available |
| Mechanism of action | Delta1-dihydrotestosterone binds to the androgen receptor, a nuclear receptor which binds the androgenic hormones testosterone and dihydrotestosterone. Once bound, the receptor/ligand complex localizes to the nucleus and acts as a DNA binding transcription factor, regulating gene expression. |
| Absorption | Not Available |
| Protein binding | Not Available |
| Biotransformation | Not Available |
| Route of elimination | Not Available |
| Toxicity | Not Available |
| Affected organisms |
|
| Interactions | |
| Drug Interactions | Not Available |
| Food Interactions | Not Available |
Targets
| Androgen receptor | |
|---|---|
| Name | Androgen receptor |
| Gene Name | AR |
| Pharmacological action | yes |
| Actions | agonist |
| References |
|
| DTHybrid score | 1.0315 |